A Novel Intelligent Thyroid Nodule Diagnosis System over Ultrasound Images Based on Deep Learning

Author(s):  
Zhike Yi ◽  
Aimin Hao ◽  
Wenfeng Song ◽  
Hongyi Li ◽  
Bowen Li
2019 ◽  
Vol 64 (23) ◽  
pp. 235013 ◽  
Author(s):  
Hiroki Tanaka ◽  
Shih-Wei Chiu ◽  
Takanori Watanabe ◽  
Setsuko Kaoku ◽  
Takuhiro Yamaguchi

Ultrasound scanning is most excellent significant diagnosis techniques utilized for thyroid nodules identification. A thyroid nodule is unnecessary cells that can develop in your base of neck which can be normal or cancerous. Many Computer added diagnosis systems (CAD) have been developed as a second opinion for radiologist. The thyroid nodules classification using machine learning and deep learning approach is latest trend which is using to improve accuracy for differentiation of thyroid nodules from benign and malignant type. In this paper we review the most recent work on CAD system which uses different feature extraction technique and classifier used for thyroid nodules classification with deep learning approach. This paper we illustrate the result obtained by these studies and highlight the limitation of each proposed methods. Moreover we summarize convolution neural network (CNN) architecture for classification of thyroid nodule. This literature review is meant at researcher but it also useful for radiologist who is interesting in CAD tool in ultrasound imaging for second opinion.


2020 ◽  
Vol 47 (9) ◽  
pp. 3952-3960 ◽  
Author(s):  
Chao Sun ◽  
Yukang Zhang ◽  
Qing Chang ◽  
Tianjiao Liu ◽  
Shaohang Zhang ◽  
...  

Author(s):  
Xia Yu ◽  
Hongjie Wang ◽  
Liyong Ma

Background: Thyroid nodules are a common clinical entity with high incidence. Ultrasound is often employed to detect and evaluate thyroid nodules. The development of an efficient automated method to detect thyroid nodules using ultrasound has the potential to reduce both physician workload and operator-dependence. Objective: To study the method of automatic detection of thyroid nodules based on deep learning using ultrasound, and to obtain the detection method with higher accuracy and better performance. Methods: A total of 1200 ultrasound images of thyroid nodules and 800 ultrasound thyroid images without nodule are collected. An improved faster R-CNN based detection method of thyroid nodule is proposed. Instead of using VGG16 as the backbone, ResNet is employed as the backbone for faster R-CNN. SVM, CNN and Faster-RCNN methods are used for thyroid nodule detection test. Precision, sensitivity, specificity and F1-score indicators are used to evaluate the detection performance of different methods. Results: The method based on deep learning is superior to that based on SVM. Faster R-CNN method and the improved method are better than CNN method. Compared with VGG16 as the backbone, RestNet101 backbone based faster R-CNN method achieves better thyroid detection effect. From the accuracy index, the proposed method is 0.084, 0.032 and 0.019 higher than SVM, CNN and faster R-CNN, respectively. Similar results can be seen in precision, sensitivity, specificity and F1-Score indicators. Conclusion: The proposed method of deep learning achieves the best performance values with the highest true positive and true negative detection compared to other methods and performs best in the detection of thyroid nodules.


IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 63482-63496 ◽  
Author(s):  
Viksit Kumar ◽  
Jeremy Webb ◽  
Adriana Gregory ◽  
Duane D. Meixner ◽  
John M. Knudsen ◽  
...  

2019 ◽  
Vol 45 ◽  
pp. S4 ◽  
Author(s):  
Hiroki Tanaka ◽  
Shih-Wei Chiu ◽  
Takanori Watanabe ◽  
Setsuko Kaoku ◽  
Takuhiro Yamaguchi

2020 ◽  
Vol 1693 ◽  
pp. 012160
Author(s):  
Jiahao Xie ◽  
Lehang Guo ◽  
Chongke Zhao ◽  
Xiaolong Li ◽  
Ye Luo ◽  
...  

2020 ◽  
Vol 185 ◽  
pp. 03021
Author(s):  
Meng Zhou ◽  
Rui Wang ◽  
Peng Fu ◽  
Yang Bai ◽  
Ligang Cui

As the most common malignancy in the endocrine system, thyroid cancer is usually diagnosed by discriminating the malignant nodules from the benign ones using ultrasonography, whose interpretation results primarily depends on the subjectivity judgement of the radiologists. In this study, we propose a novel cascade deep learning model to achieve automatic objective diagnose during ultrasound examination for assisting radiologists in recognizing benign and malignant thyroid nodules. First, the simplified U-net is employed to segment the region of interesting (ROI) of the thyroid nodules in each frame of the ultrasound image automatically. Then, to alleviate the limitation that medical training data are relatively small in size, the improved Conditional Variational Auto-Encoder (CVAE) learning the probability distribution of ROI images is trained to generate new images for data augmentation. Finally, ResNet50 is trained with both original and generated ROI images. As consequence, the deep learning model formed by the trained U-net and trained Resnet-50 cascade can achieve malignant thyroid nodule recognition with the accuracy of 87.4%, the sensitivity of 92%, and the specificity of 86.8%.


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