A biodegradable long-term contraceptive implant developed in China

Author(s):  
P.Y. Wang ◽  
C.X. Song ◽  
H.F. Sun ◽  
X.M. Cui ◽  
H.L. Shi ◽  
...  
Contraception ◽  
2014 ◽  
Vol 90 (3) ◽  
pp. 313
Author(s):  
M. Steiner ◽  
R. Callahan ◽  
D. Taylor ◽  
D. Jenkins ◽  
D. Owen ◽  
...  

2021 ◽  
Vol 10 (43) ◽  
pp. 3689-3693
Author(s):  
Dalya Thamer Ahmed

BACKGROUND Nexplanon is a pregnancy-prevention device that is both safe and reliable. It is a novel reversible long-term contraceptive technique. It's a modern long-acting contraceptive device with a subcutaneous implant that releases etonogestrel (ENG). The main objective of this research was to determine the distribution, tolerability, and adverse reactions of Nexplanon among females who used it in Baghdad and find any relationship between these side effects and the acceptability of the device among contraceptive users. METHODS This study was done via the participation of 80 women who were using Nexplanon at the time of study or had recently removed the implant; the data was obtained from a direct interview and medical records. RESULTS The total number of women enrolled for the study was 80. The mean age of contributors was 33.24 (± 2.69) years. None of the participants was nulliparous; 15 % had two children, 85 % had three or more children. Of the participants, 26.25 % and 65 % had secondary and higher education degrees respectively, while only 7 % had primary education and none of the participants had any education. 6.25 % were smokers, only 28.75 % had irregular cycle and the remaining percentage had a regular one. 57 (71.25 %) of them underwent adverse events while using the contraceptive implant, the most common one was bleeding disorders most likely in the form of light intermittent bleeding. 69 (86.25 %) from those only 18 (26.08 %) removed implant because of this irritant bleeding, the next common adverse event was headache 44 (55 %), 8 (18.18 %) of them removed the implant because of headache, 41 (51.25 %) underwent variable mood swing changes, 36 (45 %) suffered from weight gain with use of the implant, 33 (41.25 %) nausea and bowel habits changes, androgenic effects presented in 19 (23.75 %) and 10 (12.5 %) in the form of acne and hirsutism, respectively. 3 (10.34 %) of them removed the device as they could not cope with this complication, only 6 (7.5 %) suffered from low sexual desire. CONCLUSIONS Nexplanon can be a suitable alternative for women who have been adequately informed about long-term contraception but bleeding disturbances and cycle durations (> 8 days) are also key indicators for early removal. The process of consulting the patient and giving them the appropriate educational advice on this subject should be a priority before using the implant, in addition to establishing special induction and educational programs. KEY WORDS Nexplanon, Contraception Method Contraception Method, A Subcutaneous Implant and Etonogestrel.


2017 ◽  
Vol 25 (7-8) ◽  
pp. 537-539 ◽  
Author(s):  
Ee Phui Kew ◽  
Eshan Senanayake ◽  
Madava Djearaman ◽  
Ehab Bishay

An 18-year-old woman had an etonogestrel implant inserted into her left upper arm 2 years earlier for menorrhagia. Her symptoms were not well controlled and she requested the implant to be removed. However, clinicians were unable to locate the implant on her left arm. Computed tomography showed that the implant had migrated to a sub-lobar branch of the left lower lobe pulmonary artery. The long-term effect of leaving an etonogestrel implant in the pulmonary arterial system is unknown. This report adds to the small body of evidence on intravascular migration of a subdermally placed contraceptive implant.


2000 ◽  
Vol 15 (1) ◽  
pp. 118-122 ◽  
Author(s):  
Rob Beerthuizen ◽  
Agaath van Beek ◽  
Rebeca Massai ◽  
Leo Mäkäräinen ◽  
Joanneke in't Hout ◽  
...  

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


2016 ◽  
Vol 39 ◽  
Author(s):  
Mary C. Potter

AbstractRapid serial visual presentation (RSVP) of words or pictured scenes provides evidence for a large-capacity conceptual short-term memory (CSTM) that momentarily provides rich associated material from long-term memory, permitting rapid chunking (Potter 1993; 2009; 2012). In perception of scenes as well as language comprehension, we make use of knowledge that briefly exceeds the supposed limits of working memory.


1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.


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