Feature-based optimized deep residual network architecture for diabetic retinopathy detection

Author(s):  
M Kashif Yaqoob ◽  
Syed Farooq Ali ◽  
Irfan Kareem ◽  
Muhammad Moazam Fraz
Eye ◽  
2021 ◽  
Author(s):  
Lutfiah Al-Turk ◽  
James Wawrzynski ◽  
Su Wang ◽  
Paul Krause ◽  
George M. Saleh ◽  
...  

Abstract Background In diabetic retinopathy (DR) screening programmes feature-based grading guidelines are used by human graders. However, recent deep learning approaches have focused on end to end learning, based on labelled data at the whole image level. Most predictions from such software offer a direct grading output without information about the retinal features responsible for the grade. In this work, we demonstrate a feature based retinal image analysis system, which aims to support flexible grading and monitor progression. Methods The system was evaluated against images that had been graded according to two different grading systems; The International Clinical Diabetic Retinopathy and Diabetic Macular Oedema Severity Scale and the UK’s National Screening Committee guidelines. Results External evaluation on large datasets collected from three nations (Kenya, Saudi Arabia and China) was carried out. On a DR referable level, sensitivity did not vary significantly between different DR grading schemes (91.2–94.2.0%) and there were excellent specificity values above 93% in all image sets. More importantly, no cases of severe non-proliferative DR, proliferative DR or DMO were missed. Conclusions We demonstrate the potential of an AI feature-based DR grading system that is not constrained to any specific grading scheme.


2021 ◽  
Vol 13 (17) ◽  
pp. 3425
Author(s):  
Xin Zhao ◽  
Hui Li ◽  
Ping Wang ◽  
Linhai Jing

Accurate registration for multisource high-resolution remote sensing images is an essential step for various remote sensing applications. Due to the complexity of the feature and texture information of high-resolution remote sensing images, especially for images covering earthquake disasters, feature-based image registration methods need a more helpful feature descriptor to improve the accuracy. However, traditional image registration methods that only use local features at low levels have difficulty representing the features of the matching points. To improve the accuracy of matching features for multisource high-resolution remote sensing images, an image registration method based on a deep residual network (ResNet) and scale-invariant feature transform (SIFT) was proposed. It used the fusion of SIFT features and ResNet features on the basis of the traditional algorithm to achieve image registration. The proposed method consists of two parts: model construction and training and image registration using a combination of SIFT and ResNet34 features. First, a registration sample set constructed from high-resolution satellite remote sensing images was used to fine-tune the network to obtain the ResNet model. Then, for the image to be registered, the Shi_Tomas algorithm and the combination of SIFT and ResNet features were used for feature extraction to complete the image registration. Considering the difference in image sizes and scenes, five pairs of images were used to conduct experiments to verify the effectiveness of the method in different practical applications. The experimental results showed that the proposed method can achieve higher accuracies and more tie points than traditional feature-based methods.


2021 ◽  
Vol 11 ◽  
Author(s):  
Hao Fu ◽  
Weiming Mi ◽  
Boju Pan ◽  
Yucheng Guo ◽  
Junjie Li ◽  
...  

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancer types worldwide, with the lowest 5-year survival rate among all kinds of cancers. Histopathology image analysis is considered a gold standard for PDAC detection and diagnosis. However, the manual diagnosis used in current clinical practice is a tedious and time-consuming task and diagnosis concordance can be low. With the development of digital imaging and machine learning, several scholars have proposed PDAC analysis approaches based on feature extraction methods that rely on field knowledge. However, feature-based classification methods are applicable only to a specific problem and lack versatility, so that the deep-learning method is becoming a vital alternative to feature extraction. This paper proposes the first deep convolutional neural network architecture for classifying and segmenting pancreatic histopathological images on a relatively large WSI dataset. Our automatic patch-level approach achieved 95.3% classification accuracy and the WSI-level approach achieved 100%. Additionally, we visualized the classification and segmentation outcomes of histopathological images to determine which areas of an image are more important for PDAC identification. Experimental results demonstrate that our proposed model can effectively diagnose PDAC using histopathological images, which illustrates the potential of this practical application.


Author(s):  
Liming Zhao ◽  
Mingjie Li ◽  
Depu Meng ◽  
Xi Li ◽  
Zhaoxiang Zhang ◽  
...  

A deep residual network, built by stacking a sequence of residual blocks, is easy to train, because identity mappings skip residual branches and thus improve information flow. To further reduce the training difficulty, we present a simple network architecture, deep merge-and-run neural networks. The novelty lies in a modularized building block, merge-and-run block, which assembles residual branches in parallel through a merge-and-run mapping: average the inputs of these residual branches (Merge), and add the average to the output of each residual branch as the input of the subsequent residual branch (Run), respectively. We show that the merge-and-run mapping is a linear idempotent function in which the transformation matrix is idempotent, and thus improves information flow, making training easy. In comparison with residual networks, our networks enjoy compelling advantages: they contain much shorter paths and the width, i.e., the number of channels, is increased, and the time complexity remains unchanged. We evaluate the performance on the standard recognition tasks. Our approach demonstrates consistent improvements over ResNets with the comparable setup, and achieves competitive results (e.g., 3.06% testing error on CIFAR-10, 17.55% on CIFAR-100, 1.51% on SVHN). 


Complexity ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Muhammad Mateen ◽  
Junhao Wen ◽  
Nasrullah Nasrullah ◽  
Song Sun ◽  
Shaukat Hayat

In the field of ophthalmology, diabetic retinopathy (DR) is a major cause of blindness. DR is based on retinal lesions including exudate. Exudates have been found to be one of the signs and serious DR anomalies, so the proper detection of these lesions and the treatment should be done immediately to prevent loss of vision. In this paper, pretrained convolutional neural network- (CNN-) based framework has been proposed for the detection of exudate. Recently, deep CNNs were individually applied to solve the specific problems. But, pretrained CNN models with transfer learning can utilize the previous knowledge to solve the other related problems. In the proposed approach, initially data preprocessing is performed for standardization of exudate patches. Furthermore, region of interest (ROI) localization is used to localize the features of exudates, and then transfer learning is performed for feature extraction using pretrained CNN models (Inception-v3, Residual Network-50, and Visual Geometry Group Network-19). Moreover, the fused features from fully connected (FC) layers are fed into the softmax classifier for exudate classification. The performance of proposed framework has been analyzed using two well-known publicly available databases such as e-Ophtha and DIARETDB1. The experimental results demonstrate that the proposed pretrained CNN-based framework outperforms the existing techniques for the detection of exudates.


2020 ◽  
Vol 146 (3) ◽  
pp. 04020027
Author(s):  
You Zhan ◽  
Joshua Qiang Li ◽  
Guangwei Yang ◽  
Kelvin. C. P. Wang ◽  
Wenying Yu

2021 ◽  
Vol 10 (1) ◽  
pp. 413-422
Author(s):  
K. K. Yazhini ◽  
D. Loganathan

Presently, Internet of Things (IoT) becomes popular owing to diverse its application scenarios like transports, building, healthcare, etc. This study introduces an efficient IoT based diabetic retinopathy (DR) diagnosis model using Kernel Fuzzy C Means Segmentation and Residual Network. The proposed model involves a sequence of processes namely image acquisition, pre-processing, segmentation, feature extraction and classification. At the initial stage, retinal fundus image acquisition takes place which captures the retina image of the patient using head mounted camera. Next, kernel fuzzy c-means (KFCM) based segmentation process is applied to identify the diseased area. Then, the features are extracted using convolutional neural network (CNN) based residual network (ResNet) model. Finally, softmax function is employed to carry out the classification task. The validation of the presented model takes place using Kaggle DR dataset and the experimental results verified the superior performance of the presented model. The obtained results indicated that the KFCM-CNNR model has resulted to a maximum accuracy of 96.89%, sensitivity of 93.12% and specificity of 98.16%.


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