Multiplexed protein detection with an array of silicon-on-insulator microring resonators

Author(s):  
Katrien De Vosa ◽  
Jordi Gironesb ◽  
Yannick De Konincka ◽  
Etienne Schachtb ◽  
Peter Bienstmana ◽  
...  
2009 ◽  
Vol 48 (25) ◽  
pp. F90 ◽  
Author(s):  
Xiaohui Li ◽  
Ziyang Zhang ◽  
Shenying Qin ◽  
Tao Wang ◽  
Fangfei Liu ◽  
...  

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 210
Author(s):  
Kristina A. Malsagova ◽  
Tatyana O. Pleshakova ◽  
Rafael A. Galiullin ◽  
Andrey F. Kozlov ◽  
Ivan D. Shumov ◽  
...  

The detection of CA 125 protein in a solution using a silicon-on-insulator (SOI)-nanowire biosensor with n-type chip has been experimentally demonstrated. The surface of nanowires was modified by covalent immobilization of antibodies against CA 125 in order to provide the biospecificity of the target protein detection. We have demonstrated that the biosensor signal, which results from the biospecific interaction between CA 125 and the covalently immobilized antibodies, increases with the increase in the protein concentration. At that, the minimum concentration, at which the target protein was detectable with the SOI-nanowire biosensor, amounted to 1.5 × 10−16 M.


Author(s):  
Philippe Jean ◽  
Alexandre Douaud ◽  
Sophie LaRochelle ◽  
Younes Messaddeq ◽  
Wei Shi

Nanophotonics ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 669-675 ◽  
Author(s):  
Yonghui Tian ◽  
Huifu Xiao ◽  
Xiaosuo Wu ◽  
Zilong Liu ◽  
Yinghao Meng ◽  
...  

AbstractWe propose and experimentally demonstrate a silicon photonic circuit that can perform the comparison operation of two-bit digital signals based on microring resonators (MRRs). Two binary electrical signals regarded as two operands of desired comparison digital signals are applied to three MRRs to modulate their resonances through the microheaters fabricated on the top of MRRs, respectively (here, one binary electrical signal is applied to two MRRs by a 1×2 electrical power splitter, which means that the two MRRs are modulated by the same binary electrical signal). The comparison results of two binary electrical signals can be obtained at two output ports in the form of light. The proposed device is fabricated on a silicon-on-insulator substrate using the complementary metal-oxide-semiconductor fabrication process, and the dynamic characterization of the device with the operation speed of 10 kbps is demonstrated successfully.


2003 ◽  
Vol 15 (7) ◽  
pp. 921-923 ◽  
Author(s):  
A. Vorckel ◽  
M. Monster ◽  
W. Henschel ◽  
P.H. Bolivar ◽  
H. Kurz

2020 ◽  
Author(s):  
Massimo Borghi ◽  
Mattia Mancinelli ◽  
Davide Bazzanella ◽  
Lorenzo Pavesi

2018 ◽  
Vol 57 (05) ◽  
pp. 1 ◽  
Author(s):  
Chaoying Zhao ◽  
Lei Zhang ◽  
Jiaxiao Liao

2010 ◽  
Vol 35 (5) ◽  
pp. 784 ◽  
Author(s):  
Michael L. Cooper ◽  
Greeshma Gupta ◽  
Jung S. Park ◽  
Mark A. Schneider ◽  
Ivan B. Divliansky ◽  
...  

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