Minimally invasive tissue engineering composites and cell printing - Injectable composites combined with tissue-printing technology for improved bioengineered devices

2003 ◽  
Vol 22 (5) ◽  
pp. 84-91 ◽  
Author(s):  
K.J.L. Burg ◽  
T. Boland
Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 934
Author(s):  
Jongmin Kim ◽  
Jeong Sik Kong ◽  
Hyeonji Kim ◽  
Wonil Han ◽  
Jae Yon Won ◽  
...  

Retinal degeneration is a leading cause of incurable vision loss and blindness. The increasing incidence of retinal degeneration has triggered research into the development of in vitro retinal models for drug development and retinal alternatives for transplantation. However, the complex retinal structure and the retinal microenvironment pose serious challenges. Although 3D cell printing technology has been widely used in tissue engineering, including in vitro model development and regeneration medicine, currently available bioinks are insufficient to recapitulate the complex extracellular matrix environment of the retina. Therefore, in this study, we developed a retinal decellularized extracellular matrix (RdECM) from the porcine retina and evaluated its characteristics. The RdECM conserved the ECM components from the native retina without cellular components. Then, we mixed the RdECM with collagen to form a bioink and confirmed its suitability for 3D cell printing. We further studied the effect of the RdECM bioink on the differentiation of Muller cells. The retinal protective effect of the RdECM bioink was confirmed through a retinal degeneration animal model. Thus, we believe that the RdECM bioink is a promising candidate for retinal tissue engineering.


Biomaterials ◽  
2012 ◽  
Vol 33 (6) ◽  
pp. 1782-1790 ◽  
Author(s):  
Roberto Gaetani ◽  
Peter A. Doevendans ◽  
Corina H.G. Metz ◽  
Jacqueline Alblas ◽  
Elisa Messina ◽  
...  

2020 ◽  
Vol 16 ◽  
Author(s):  
Wei Liu ◽  
Shifeng Liu ◽  
Yunzhe Li ◽  
Peng Zhou ◽  
Qian ma

Abstract:: Surgery to repair damaged tissue, which is caused by disease or trauma, is being carried out all the time, and a desirable treatment is compelling need to regenerate damaged tissues to further improve the quality of human health. Therefore, more and more research focus on exploring the most suitable bionic design to enrich available treatment methods. 3D-printing, as an advanced materials processing approach, holds promising potential to create prototypes with complex constructs that could reproduce primitive tissues and organs as much as possible or provide appropriate cell-material interfaces. In a sense, 3D printing promises to bridge between tissue engineering and bionic design, which can provide an unprecedented personalized recapitulation with biomimetic function under the precise control of the composition and spatial distribution of cells and biomaterials. This article describes recent progress in 3D bionic design and the potential application prospect of 3D printing regenerative medicine including 3D printing biomimetic scaffolds and 3D cell printing in tissue engineering.


2010 ◽  
Vol 36 (4) ◽  
pp. 295-304
Author(s):  
Gregory Gene Steiner ◽  
Dainon M. Steiner ◽  
Melis P. Herbias ◽  
Roslynn Steiner

Abstract Sinus lift surgery has become more common as patients choose dental implants for tooth replacement. The recent development of a graft material that stimulates osteogenesis coupled with the application of tissue engineering principles has allowed for refinement of this surgical modality. A simple nontraumatic subantral sinus lift microsurgery is presented. This sinus lift microsurgery resulted in a 97% implant success rate.


Bioprinting ◽  
2018 ◽  
Vol 12 ◽  
pp. e00030 ◽  
Author(s):  
Bin Wu ◽  
Shihao Li ◽  
Jia Shi ◽  
Sanjairaj Vijayavenkataraman ◽  
Wen Feng Lu ◽  
...  

2018 ◽  
Vol 4 (11) ◽  
pp. 3691-3703 ◽  
Author(s):  
Miles Montgomery ◽  
Locke Davenport Huyer ◽  
Dawn Bannerman ◽  
Mohammad Hossein Mohammadi ◽  
Genevieve Conant ◽  
...  

2020 ◽  
Vol 12 (3) ◽  
pp. 035016 ◽  
Author(s):  
Yu Song ◽  
Xiaolei Su ◽  
Kevin F. Firouzian ◽  
Yongcong Fang ◽  
Ting Zhang ◽  
...  

2019 ◽  
Vol 7 (38) ◽  
pp. 5742-5761 ◽  
Author(s):  
Stuart A. Young ◽  
Hossein Riahinezhad ◽  
Brian G. Amsden

Injectable, in situ-forming hydrogels can improve cell delivery in tissue engineering applications by facilitating minimally invasive delivery to irregular defect sites and improving cell retention and survival.


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