Using Kalman Filter to Process Auditory Brainstem Responses in Subjects with Normal Hearing

2019 ◽  
Author(s):  
Dan Wang ◽  
Jingqian Tan ◽  
Yanbing Jiang ◽  
Mingxing Zhu ◽  
Zhenzhen Liu ◽  
...  
Keyword(s):  
Kalman Filter ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Auditory Brainstem Responses

Chirp-Evoked Auditory Brainstem Response in Children: A Review

2015 ◽  
Vol 24 (4) ◽  
pp. 573-583 ◽  
Author(s):  
Gabriel Anne Bargen
Keyword(s):  
Auditory Brainstem Response ◽  
Pediatric Population ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Auditory Brainstem Responses ◽  
Test Time ◽  
Future Research ◽  
Inclusion Criteria ◽  
Qualitative Synthesis ◽  
Brainstem Response

Purpose The aim of this study was to assess the use of the chirp stimulus to record auditory brainstem responses in the pediatric population via a traditional review. Method An electronic search of the literature and a hand search of the literature were conducted. Studies that utilized chirp stimuli within the pediatric population that met all of the inclusion criteria were included in this review. Qualitative synthesis and interpretation of the data were completed. Results Seven studies that met the inclusion criteria were included in the review. Chirp stimuli produce auditory brainstem response (ABR) waveform amplitudes in children similar to those in adults when presented at moderate to low frequency levels. Latency data from chirp stimuli are not consistent when stimulus presentation rates are altered. Test–retest reliability when using the chirp stimulus was found to be good, as were sensitivity and specificity of chirp-evoked ABRs utilized in a newborn hearing screening protocol. Conclusion Reviewed studies indicated that when presented at 60 dB nHL or lower, broadband chirp–generated ABRs have larger amplitudes than click-generated ABRs in children with normal hearing. Utilization of chirp stimuli decreases test time because waveforms are easier to detect with increased synchronization. Further research should focus on correlating chirp thresholds with behavioral hearing thresholds. Given the variance of results in these select studies, future research should also evaluate latency findings and focus on developing normative data for infants with hearing impairment and normal hearing.

scholarly journals Availability and safety assessment of infrared neural stimulation at high repetition rate through an implantable optrode

2021 ◽  
Vol 14 (03) ◽  
pp. 2150014
Author(s):  
Yaqin Wan ◽  
Meiqun Wang ◽  
Shaorong Zhang ◽  
Bingbin Xie
Keyword(s):  
Repetition Rate ◽  
Guinea Pigs ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
High Repetition Rate ◽  
Neural Stimulation ◽  
Auditory Brainstem Responses ◽  
High Repetition ◽  
Thermal Detectors ◽  
Stimulus Site

An implantable optrode with micro-thermal detectors was designed to investigate the availability and safety of INS using high repetition rates. Optical auditory brainstem responses (oABRs) were recorded in normal-hearing guinea pigs, and the energy thresholds, pulse durations, and amplitudes evoked by the varied stimulus repetitions were analyzed. Stable oABRs could be evoked through INS even as the repetition rate of stimulation reached 19[Formula: see text]kHz. The energy threshold of oABRs was elevated, the amplitudes decreased as pulse durations increased and repetition rates were higher, and the latencies were delayed as the pulse durations increased. The temperature variation curves on the site of stimulation significantly increased as the pulse duration increased to 400 [Formula: see text]s. INS elevated the temperature around the stimulus site area via thermal accumulation during radiation, especially when higher repetition stimuli were used. Our results demonstrate that high repetition infrared stimulations can safely evoke stable and available oABRs in normal-hearing guinea pigs.

scholarly journals Elimination of peripheral auditory pathway activation does not affect motor responses from ultrasound neuromodulation

2018 ◽  
Author(s):  
Morteza Mohammadjavadi ◽  
Patrick Peiyong Ye ◽  
Anping Xia ◽  
Julian Brown ◽  
Gerald Popelka ◽  
...  
Keyword(s):  
Auditory System ◽  
Focused Ultrasound ◽  
Response Duration ◽  
Brain Structures ◽  
Auditory Pathway ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Auditory Brainstem Responses ◽  
Motor Responses ◽  
Peripheral Auditory System

AbstractRecent studies in a variety of animal models including rodents, monkeys, and humans suggest that transcranial focused ultrasound (tFUS) has considerable promise for non-invasively modulating neural activity with the ability to target deep brain structures. However, concerns have been raised that motor responses evoked by tFUS may be due to indirect activation of the auditory pathway rather than direct activation of motor circuits. In this study, tFUS-induced electromyography (EMG) signals were recorded and analyzed in wild-type (WT) normal hearing mice and two strains of genetically deaf mice to examine the involvement of the peripheral auditory system in tFUS-stimulated motor responses. In addition, auditory brainstem responses (ABRs) were measured to elucidate the effect of the tFUS stimulus envelope on auditory and motor responses. We also varied the tFUS stimulation duration to measure its effect on motor response duration. We show, first, that the sharp edges in a tFUS rectangular envelope stimulus activate the peripheral afferent auditory pathway and, second, that smoothing these edges eliminates the auditory responses without affecting the motor responses in normal hearing WT mice. We further show that by eliminating peripheral auditory activity using two different strains of deaf knockout mice, motor responses are the same as in normal hearing WT mice. Finally, we demonstrate a high correlation between tFUS pulse duration and EMG response duration. These results support the concept that tFUS-evoked motor responses are not a result of stimulation of the peripheral auditory system.

Neurophysiological aspects of brainstem processing of speech stimuli in audiometric-normal geriatric population

2016 ◽  
Vol 131 (3) ◽  
pp. 239-244 ◽  
Author(s):  
M S Ansari ◽  
R Rangasayee ◽  
M A H Ansari
Keyword(s):  
Speech Perception ◽  
Auditory Brainstem Response ◽  
Clinical Decision Making ◽  
Speech Sound ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Auditory Brainstem Responses ◽  
Spectral Amplitude ◽  
Brainstem Response ◽  
Noisy Conditions

AbstractObjective:Poor auditory speech perception in geriatrics is attributable to neural de-synchronisation due to structural and degenerative changes of ageing auditory pathways. The speech-evoked auditory brainstem response may be useful for detecting alterations that cause loss of speech discrimination. Therefore, this study aimed to compare the speech-evoked auditory brainstem response in adult and geriatric populations with normal hearing.Methods:The auditory brainstem responses to click sounds and to a 40 ms speech sound (the Hindi phoneme |da|) were compared in 25 young adults and 25 geriatric people with normal hearing. The latencies and amplitudes of transient peaks representing neural responses to the onset, offset and sustained portions of the speech stimulus in quiet and noisy conditions were recorded.Results:The older group had significantly smaller amplitudes and longer latencies for the onset and offset responses to |da| in noisy conditions. Stimulus-to-response times were longer and the spectral amplitude of the sustained portion of the stimulus was reduced. The overall stimulus level caused significant shifts in latency across the entire speech-evoked auditory brainstem response in the older group.Conclusion:The reduction in neural speech processing in older adults suggests diminished subcortical responsiveness to acoustically dynamic spectral cues. However, further investigations are needed to encode temporal cues at the brainstem level and determine their relationship to speech perception for developing a routine tool for clinical decision-making.

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