Diagnosis of breast cancer with an innovative adaptive Support Vector Machine

Author(s):  
Engin Karacan ◽  
Erdal Kilic
Algorithms ◽  
2019 ◽  
Vol 12 (7) ◽  
pp. 135
Author(s):  
Cai ◽  
Liu ◽  
Luo ◽  
Du ◽  
Tang

Microcalcification is the most important landmark information for early breast cancer. At present, morphological artificial observation is the main method for clinical diagnosis of such diseases, but it is easy to cause misdiagnosis and missed diagnosis. The present study proposes an algorithm for detecting microcalcification on mammography for early breast cancer. Firstly, the contrast characteristics of mammograms are enhanced by Contourlet transformation and morphology (CTM). Secondly, split the ROI by the improved K-means algorithm. Thirdly, calculate grayscale feature, shape feature, and Histogram of Oriented Gradient (HOG) for the ROI region. The Adaptive support vector machine (ASVM) is used as a tool to classify the rough calcification point and the false calcification point. Under the guidance of a professional doctor, 280 normal images and 120 calcification images were selected for experimentation, of which 210 normal images and 90 images with calcification images were used for training classification. The remaining 100 are used to test the algorithm. It is found that the accuracy of the automatic classification results of the Adaptive support vector machine (ASVM) algorithm reaches 94%, and the experimental results are superior to similar algorithms. The algorithm overcomes various difficulties in microcalcification detection and has great clinical application value.


2010 ◽  
Vol 36 (3) ◽  
pp. 1503-1510 ◽  
Author(s):  
U. Rajendra Acharya ◽  
E. Y. K. Ng ◽  
Jen-Hong Tan ◽  
S. Vinitha Sree

2011 ◽  
Vol 36 (4) ◽  
pp. 2505-2519 ◽  
Author(s):  
Hui-Ling Chen ◽  
Bo Yang ◽  
Gang Wang ◽  
Su-Jing Wang ◽  
Jie Liu ◽  
...  

Author(s):  
Yifeng Dou ◽  
Wentao Meng

As one of the most vulnerable cancers of women, the incidence rate of breast cancer in China is increasing at an annual rate of 3%, and the incidence is younger. Therefore, it is necessary to conduct research on the risk of breast cancer, including the cause of disease and the prediction of breast cancer risk based on historical data. Data based statistical learning is an important branch of modern computational intelligence technology. Using machine learning method to predict and judge unknown data provides a new idea for breast cancer diagnosis. In this paper, an improved optimization algorithm (GSP_SVM) is proposed by combining genetic algorithm, particle swarm optimization and simulated annealing with support vector machine algorithm. The results show that the classification accuracy, MCC, AUC and other indicators have reached a very high level. By comparing with other optimization algorithms, it can be seen that this method can provide effective support for decision-making of breast cancer auxiliary diagnosis, thus significantly improving the diagnosis efficiency of medical institutions. Finally, this paper also preliminarily explores the effect of applying this algorithm in detecting and classifying breast cancer in different periods, and discusses the application of this algorithm to multiple classifications by comparing it with other algorithms.


Worldwide, breast cancer is the leading type of cancer in women accounting for 25% of all cases. Survival rates in the developed countries are comparatively higher with that of developing countries. This had led to the importance of computer aided diagnostic methods for early detection of breast cancer disease. This eventually reduces the death rate. This paper intents the scope of the biomarker that can be used to predict the breast cancer from the anthropometric data. This experimental study aims at computing and comparing various classification models (Binary Logistic Regression, Ball Vector Machine (BVM), C4.5, Partial Least Square (PLS) for Classification, Classification Tree, Cost sensitive Classification Tree, Cost sensitive Decision Tree, Support Vector Machine for Classification, Core Vector Machine, ID3, K-Nearest Neighbor, Linear Discriminant Analysis (LDA), Log-Reg TRIRLS, Multi Layer Perceptron (MLP), Multinomial Logistic Regression (MLR), Naïve Bayes (NB), PLS for Discriminant Analysis, PLS for LDA, Random Tree (RT), Support Vector Machine SVM) for the UCI Coimbra breast cancer dataset. The feature selection algorithms (Backward Logit, Fisher Filtering, Forward Logit, ReleifF, Step disc) are worked out to find out the minimum attributes that can achieve a better accuracy. To ascertain the accuracy results, the Jack-knife cross validation method for the algorithms is conducted and validated. The Core vector machine classification algorithm outperforms the other nineteen algorithms with an accuracy of 82.76%, sensitivity of 76.92% and specificity of 87.50% for the selected three attributes, Age, Glucose and Resistin using ReleifF feature selection algorithm.


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