Topology Driven Analysis of Protein - Protein Interactome for Prioritizing Key Comorbid Genes via Sub Graph based Average Path Length Centrality

Author(s):  
Nikhila T Suresh ◽  
Vimina E R ◽  
U Krishnakumar
2019 ◽  
Vol 24 (2) ◽  
pp. 88-104
Author(s):  
Ilham Aminudin ◽  
Dyah Anggraini

Banyak bisnis mulai muncul dengan melibatkan pengembangan teknologi internet. Salah satunya adalah bisnis di aplikasi berbasis penyedia layanan di bidang moda transportasi berbasis online yang ternyata dapat memberikan solusi dan menjawab berbagai kekhawatiran publik tentang layanan transportasi umum. Kemacetan lalu lintas di kota-kota besar dan ketegangan publik dengan keamanan transportasi umum diselesaikan dengan adanya aplikasi transportasi online seperti Grab dan Gojek yang memberikan kemudahan dan kenyamanan bagi penggunanya Penelitian ini dilakukan untuk menganalisa keaktifan percakapan brand jasa transportasi online di jejaring sosial Twitter berdasarkan properti jaringan. Penelitian dilakukan dengan dengan mengambil data dari percakapan pengguna di social media Twitter dengan cara crawling menggunakan Bahasa pemrograman R programming dan software R Studio dan pembuatan model jaringan dengan software Gephy. Setelah itu data dianalisis menggunakan metode social network analysis yang terdiri berdasarkan properti jaringan yaitu size, density, modularity, diameter, average degree, average path length, dan clustering coefficient dan nantinya hasil analisis akan dibandingkan dari setiap properti jaringan kedua brand jasa transportasi Online dan ditentukan strategi dalam meningkatkan dan mempertahankan keaktifan serta tingkat kehadiran brand jasa transportasi online, Grab dan Gojek.


Fractals ◽  
2019 ◽  
Vol 27 (02) ◽  
pp. 1950010
Author(s):  
DAOHUA WANG ◽  
YUMEI XUE ◽  
QIAN ZHANG ◽  
MIN NIU

Many real systems behave similarly with scale-free and small-world structures. In this paper, we generate a special hierarchical network and based on the particular construction of the graph, we aim to present a study on some properties, such as the clustering coefficient, average path length and degree distribution of it, which shows the scale-free and small-world effects of this network.


Geofluids ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Yuhao Hu ◽  
Guannan Liu ◽  
Feng Gao ◽  
Fengtian Yue ◽  
Tao Gao

The rational characterization and quantitative analysis of the complex internal pore structure of rock is the foundation to solve many underground engineering problems. In this paper, CT imaging technology is used to directly characterize the three-dimensional pore network topology of sandstone with different porosity. Then, in view of the problem, which is difficult to quantify the detailed topological structure of the sandstone pore networks in the previous study, the new complex network theory is used to characterize the pore structure. PageRank algorithm is based on the number of connections between targets as a measure index to rank the targets, so the network degree distribution, average path length, clustering coefficient, and robustness based on PageRank algorithm and permeability-related topological parameters are studied. The research shows that the degree distribution of sandstone pore network satisfies power law distribution, and it can be characterized by scale-free network model. The permeability of rock is inversely proportional to the average path length of sandstone network. The sandstone pore network has strong robustness to random disturbance, while a small number of pores with special topological properties play a key role in the macroscopic permeability of sandstone. This study attempts to provide a new perspective of quantifying the microstructure of the pore network of sandstone and revealing the microscopic structure mechanism of macroscopic permeability of pore rocks.


2019 ◽  
Vol 11 (7) ◽  
pp. 2007 ◽  
Author(s):  
Guo-Ling Jia ◽  
Rong-Guo Ma ◽  
Zhi-Hua Hu

Urban public transportation contributes greatly to sustainable urban development. An urban public transportation network is a complex system. It is meaningful for theory and practice to analyze the topological structure of an urban public transportation network and explore the spatial structure of an urban transportation network so as to mitigate and prevent traffic congestion and achieve sustainability. By examining the Xi’an bus network, the degree distribution, average path length, aggregation coefficient, and betweenness centrality of the bus station network were computed using models in complex network theory. The results show that the node degrees of the Xi’an bus network are unevenly distributed and present a polarization diagram with long average path length and high aggregation. A model based on betweenness and its solution method was developed to improve the public transportation network’s sustainability and discuss the possibility of optimizing the sustainability by network analyzing methods.


Complexity ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Haifeng Du ◽  
Xiaochen He ◽  
Wei Du ◽  
Marcus W. Feldman

Optimizing average path length (APL) by adding shortcut edges has been widely discussed in connection with social networks, but the relationship between network diameter and APL is generally ignored in the dynamic optimization of APL. In this paper, we analyze this relationship and transform the problem of optimizing APL into the problem of decreasing diameter to 2. We propose a mathematic model based on a memetic algorithm. Experimental results show that our algorithm can efficiently solve this problem as well as optimize APL.


Fractals ◽  
2018 ◽  
Vol 26 (03) ◽  
pp. 1850039 ◽  
Author(s):  
YUMEI XUE ◽  
DONGXUE ZHOU

In this paper, we construct a special network based on the construction of the Sierpinski carpet. Using the self-similarity and renewal theorem, we obtain the asymptotic formula for the average path length of our evolving network.


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