Optimization of Hetero-Gate-Dielectric Tunnel FET for Label-Free Detection and Identification of Biomolecules

2020 ◽  
Vol 67 (5) ◽  
pp. 2157-2164
Author(s):  
Sampriti Ghosh ◽  
Avik Chattopadhyay ◽  
Suchismita Tewari
Keyword(s):  
Gate Dielectric ◽  
Label Free ◽  
Tunnel Fet ◽  
Detection And Identification ◽  
Label Free Detection

scholarly journals Biologically sensitive field-effect transistors: from ISFETs to NanoFETs

2016 ◽  
Vol 60 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Vivek Pachauri ◽  
Sven Ingebrandt
Keyword(s):  
Field Effect ◽  
Gate Dielectric ◽  
Gate Dielectrics ◽  
Field Effect Transistors ◽  
Silicon Nanowire ◽  
Label Free ◽  
Biomolecular Detection ◽  
New Device ◽  
Label Free Detection ◽  
History Of

Biologically sensitive field-effect transistors (BioFETs) are one of the most abundant classes of electronic sensors for biomolecular detection. Most of the time these sensors are realized as classical ion-sensitive field-effect transistors (ISFETs) having non-metallized gate dielectrics facing an electrolyte solution. In ISFETs, a semiconductor material is used as the active transducer element covered by a gate dielectric layer which is electronically sensitive to the (bio-)chemical changes that occur on its surface. This review will provide a brief overview of the history of ISFET biosensors with general operation concepts and sensing mechanisms. We also discuss silicon nanowire-based ISFETs (SiNW FETs) as the modern nanoscale version of classical ISFETs, as well as strategies to functionalize them with biologically sensitive layers. We include in our discussion other ISFET types based on nanomaterials such as carbon nanotubes, metal oxides and so on. The latest examples of highly sensitive label-free detection of deoxyribonucleic acid (DNA) molecules using SiNW FETs and single-cell recordings for drug screening and other applications of ISFETs will be highlighted. Finally, we suggest new device platforms and newly developed, miniaturized read-out tools with multichannel potentiometric and impedimetric measurement capabilities for future biomedical applications.

Junctionless based dielectric modulated electrically doped tunnel FET based biosensor for label‐free detection

2018 ◽  
Vol 13 (4) ◽  
pp. 452-456 ◽  
Author(s):  
Bandi Venkata Chandan ◽  
Kaushal Nigam ◽  
Dheeraj Sharma
Keyword(s):  
Label Free ◽  
Tunnel Fet ◽  
Label Free Detection

A Dielectric-Modulated Tunnel-FET-Based Biosensor for Label-Free Detection: Analytical Modeling Study and Sensitivity Analysis

2012 ◽  
Vol 59 (10) ◽  
pp. 2809-2817 ◽  
Author(s):  
Rakhi Narang ◽  
K. V. Sasidhar Reddy ◽  
Manoj Saxena ◽  
R. S. Gupta ◽  
Mridula Gupta
Keyword(s):  
Sensitivity Analysis ◽  
Analytical Modeling ◽  
Label Free ◽  
Tunnel Fet ◽  
Label Free Detection ◽  
Modeling Study
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