A Factor Analysis Framework for Power Spectra Separation and Multiple Emitter Localization

2015 ◽  
Vol 63 (24) ◽  
pp. 6581-6594 ◽  
Author(s):  
Xiao Fu ◽  
Nicholas D. Sidiropoulos ◽  
John H. Tranter ◽  
Wing-Kin Ma
Biostatistics ◽  
2020 ◽  
Author(s):  
Andrea Rau ◽  
Regina Manansala ◽  
Michael J Flister ◽  
Hallgeir Rui ◽  
Florence Jaffrézic ◽  
...  

Summary Malignant progression of normal tissue is typically driven by complex networks of somatic changes, including genetic mutations, copy number aberrations, epigenetic changes, and transcriptional reprogramming. To delineate aberrant multi-omic tumor features that correlate with clinical outcomes, we present a novel pathway-centric tool based on the multiple factor analysis framework called padma. Using a multi-omic consensus representation, padma quantifies and characterizes individualized pathway-specific multi-omic deviations and their underlying drivers, with respect to the sampled population. We demonstrate the utility of padma to correlate patient outcomes with complex genetic, epigenetic, and transcriptomic perturbations in clinically actionable pathways in breast and lung cancer.


2020 ◽  
Vol 20 (2) ◽  
pp. 60-76
Author(s):  
T. Joe-Asare ◽  
N. Amegbey ◽  
E. Stemn

In an attempt to incorporate human factors into technical failures as accident causal factors, researchers have promoted the concept of human factor analysis. Human factor analysis models seek to identify latent conditions within the system that influence the operator’s action to trigger an accident.  For an effective application of human factor analysis models, a domain-specific model is recommended. Most existing models are developed with category/subcategory peculiar to a particular domain. This presents challenges and hinders effective application outside the domain developed for. This paper sought to propose a human factor analysis framework for Ghana’s mining industry. A comparative study was carried out between three dominated accident causation models and investigation methods in literature; AcciMap, HFACS, and STAMP. The comparative assessment showed that HFACS is suitable for incident data analysis based on the following reason; ease of learning and use, suitability for multiple incident analysis and statistical quantification of trends and patterns, and high inter and intra-coder reliability. A thorough study was done on HFACS and its derivative. Based on recommendations and research findings on HFACS from literature, Human Factor Analysis, and Classification System – Ghana Mining Industry (HFACS-GMI) was proposed. The HFACS-GMI has 4 tiers, namely; External influence/factor, Organisational factor, Local Workplace/Individual Condition and, Unsafe Act. A partial list of causal factors under each tier was generated to serve as a guide during incident coding and investigation. The HFACS-GMI consists of 18 subcategories and these have been discussed. The HFACS-GMI is specific to the Ghanaian Mines and could potentially help in identifying causal and contributing factors of an accident during an incident investigation and data analysis.   Keywords: Human Factor Analysis, Causal Factor, Causation Model, Mining Industry


2018 ◽  
Vol 23 (2) ◽  
pp. 125-157 ◽  
Author(s):  
Tony Berber Sardinha

Abstract This paper presents a study that sought to identify the dimensions of variation underlying a corpus of Internet texts, using Biber’s (1988) multi-dimensional (MD) analysis framework. The corpus was compiled following the method proposed by Biber (1993), according to which the size of each register subcorpus should be determined based on the linguistic variation across the texts. The corpus was tagged using the Biber Tagger and the features were counted and submitted to a factor analysis, which suggested three factors. The factors were interpreted as three dimensions of variation: involved, interactive discourse versus informational focus; expression of stance: interactional evidentiality; and expression of stance: interactional affect. The amount of register variation captured by the register distinctions on the dimensions ranged from 8.7% to 57.1%. Dimension 1 corroborate the oral/involved versus literate/informational distinction defined in previous MD studies of non-Internet registers, whereas Dimensions 2 and 3 highlight the important role played by stance in social media.


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