scholarly journals A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review

2021 ◽  
Vol 48 (3) ◽  
pp. 291-309
Author(s):  
Fateme Kooshki ◽  
Helda Tutunchi ◽  
Mahdi Vajdi ◽  
Arash Karimi ◽  
Hamid Reza Niazkar ◽  
...  
2020 ◽  
Vol 26 (1) ◽  
pp. 70-76
Author(s):  
Ediléa Monteiro de Oliveira ◽  
Andressa Karoline Pinto de Lima Ribeiro ◽  
Dayse Danielle de Oliveira Silva ◽  
Erica Feio Carneiro Nunes ◽  
Gisely Santiago Santos ◽  
...  

ABSTRACT Introduction: Diabetes mellitus is accompanied by increased formation of reactive oxygen species (ROS) and decreased antioxidant capacity, leading to oxidative damage to cellular components. There is evidence to suggest that regular physical training positively changes oxidative homeostasis in the cells and tissues by lowering basal levels of oxidative damage, increasing resistance to oxidative stress. Objective: To verify the possible effects of aerobic physical training and resistance on glycemia and oxidative metabolism, and to determine whether there is any difference in outcomes resulting from different types of training in sedentary people with Type 2 Diabetes Mellitus (T2DM). Methods: A systematic review of controlled and randomized trials based on PRISMA. The databases LILACS, IBECS, Pubmed/MEDLINE, Cochrane Library, SciELO, PEDro, ScienceDirect and BIREME were searched, combining the descriptors type 2 diabetes mellitus, resistance training, aerobic exercise and oxidative stress in Portuguese, English and Spanish. The methodological quality of the papers was assessed by the PEDro scale. The data were read, analyzed, extracted and summarized. Results: Of the 1386 papers retrieved, only five met the inclusion criteria. The five selected papers, consisting of controlled and randomized clinical trials, were summarized. Conclusion: There have been many published studies reporting on exercises and diabetes. However, there is limitation when it comes to comparing their results. The variability of research methods and measurement instruments used makes it difficult to draw conclusions as to which physical training modality is most effective in reducing glycemic levels and oxidative stress in sedentary individuals with T2DM, considering that in each study analyzed in this review, the response to these variables is different. In future research, it would be important to standardize exercise modality, intensity, training time and evaluation parameters. Level of evidence I; Systematic review of RCTs (Randomized controlled trials).


PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0184122 ◽  
Author(s):  
Saeed Sadigh-Eteghad ◽  
Alireza Majdi ◽  
Sarah K. McCann ◽  
Javad Mahmoudi ◽  
Manouchehr S. Vafaee ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0190328
Author(s):  
Saeed Sadigh-Eteghad ◽  
Alireza Majdi ◽  
Sarah K. McCann ◽  
Javad Mahmoudi ◽  
Manouchehr S. Vafaee ◽  
...  

2021 ◽  
Vol 17 ◽  
Author(s):  
V. Venugopal ◽  
S. Geethanjali ◽  
S. Poonguzhali ◽  
R. Padmavathi ◽  
Shriraam Mahadevan ◽  
...  

Background: Diabetes mellitus has a significant impact on public health. Oxidative stress plays a major role in the pathophysiology of type 2 diabetes mellitus (T2DM), leading to various complications of T2DM. Yoga is being widely used in the management of T2DM. The primary objective of this systematic review and meta-analysis is to understand the effects of yoga on oxidative stress parameters among adult patients diagnosed with T2DM. Materials and methods: Electronic databases such as PubMed, Scopus, Cochrane Library and Science direct from inception till March 2020 were searched to obtain eligible studies. Study designs of all nature were included (except case studies and reviews). The primary outcome was malondialdehyde (MDA) and secondary outcomes included fasting plasma glucose, HbA1C and superoxide dismutase (SOD) levels. Results: A total of four trials with a total of 440 patients met the inclusion criteria. The results of meta-analysis indicated that yoga significantly reduced MDA (SMD: -1.4 ; 95% CI -2.66 to -0.13; P = 0.03; I2 = 97%), fasting plasma glucose levels (SMD: –1.87: 95% CI -3.83 to -0.09; P = 0.06;I2= 99%), and HbA1c (SMD: -1.92; 95% CI - 3.03 to -0.81; P = 0.0007; I2 = 92%) in patients with T2DM. No such effect was found for SOD (SMD: -1.01; 95% CI -4.41 to 2.38; P = 0.56; I2= 99%). Conclusion: The available evidence suggests that yoga reduces MDA, fasting plasma glucose and HbA1C, and thus would be beneficial in the management of T2DM as a complementary therapy. However, considering the limited number of studies and its heterogeneity, further robust studies are necessary to strengthen our findings and investigate the long-term benefits of yoga.


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