Behaviour of relative evapotranspiration with agrometeorological stress indices in wheat

Complex behaviour of stress indices with relative evapotranspiration was observed in early and late sown wheat, however, under normal sown conditions it was linearly decreasing. Predawn leaf water potential and transpiration rate proved to be a stable stress index parameter for characterizing the internal moisture status in the plant as compared to the canopy temperature and stomatal resistance under stress conditions in wheat. Since it is easy to quantify canopy/leaf temperature and within seasonal variations it is widely used for scheduling irrigation and quantigying moisture stress effects on growth and development in wheat.

Pomegranate Seed Extract: A Strong Antioxidant against Benign Prostatic Hyperplasia Induced Oxidative Stress in Albino Wistar Rats

Aim: The aim of this study was to assess the antioxidant properties of ethanolic and aqueous extracts of Punica granatum (Pomegranate) seed in testosterone induced benign prostate hyperplastic albino Wistar rats. Study design: This study is an interventional study. Place and Duration of Study: The experimental aspect of this study was conducted at the animal house, Department of Pharmacology, University of Port Harcourt between April and September, 2019. Methodology: Seventy (70) adult albino male wistar rats were used for this study. They were divided into 12 groups of 5 rats each and fed with commercial rat diet and clean drinking water. Aqueous and ethanolic extracts of Punica granatum seed were prepared using the maceration method. Benign Prostate Hyperplasia was induced in rats after they submitted to bilateral orchiectomy by daily injections of testosterone propionate (TP) (4 mg/kg b.wt.sc). Rats were treated with 500 or 1500 mg/kg b.wt. of aqueous or ethanoI extracts of Punica granatum seed, dutasteride or in combination. Administration of extracts was done by gavage. Plasma total oxidant status (TOS), total antioxidant status (TAS), superoxide dismutase (SOD) activity, were analyzed using sandwich ELISA Kits by Shanghai Korain Biotech Co., Ltd, China, while oxidative stress indices (OSI) were calculated. Statistical analysis was done using SPSS version 22.0 of Windows Stat Pac and p values less than 0.05 were considered statistically significant. Results: The results showed that the mean TOS, TAS, SOD and OSI for the rats in the normal control group were 1.66±0.2U/ml, 2.71±0.25U/ml, 41.8±2.9pg/ml and 0.62±0.10 respectively. After BPH induction (group 2), the values were 3.25±0.5U/ml,1.17±0.14U/ml, 23.38±2.09 pg/ml and 2.81±0.60pg/ml respectively. There were significant decreases for TOS and OSI, and significant increases for TAS and SOD when the rats where treated with lower and higher doses of both aqueous and ethanolic extracts of Punica granatum and Dutasteride. Conclusion: In conclusion, both doses of Punica granatum seed for ethanolic and aqueous extracts individually and in combination and with dutasteride markedly reduced total oxidant status, oxidative stress indices and improved the activities of antioxidant parameters like superoxide dismutase and total antioxidant status.

Assessing the Climatological Relationship between Heatstroke Risk and Heat Stress Indices in 47 Prefectures in Japan

This study provides a decade-long link between summer heatstroke incidence and certain heat stress indices in 47 prefectures of Japan. The results for each prefecture were determined from the age-adjusted heatstroke incidence rate (TRadj) with heatstroke patients transported by ambulance, as well as from the daily maximum temperature (TEMPmax), maximum wet-bulb globe temperature (WBGTmax), and maximum universal thermal climate index (UTCImax) recorded from July to September of 2010–2019. The UTCImax relatively increased the vulnerability in many prefectures of northern Japan more distinctly than the other indices. In the following analysis, the ratio of the TRadj of the hottest to coolest months using the UTCImax was defined as the heatstroke risk of the hottest to coolest (HRHC). Overall, the HRHC varied approximately from 20 to 40 in many prefectures in the past decade. In contrast, for the same analysis performed in each month, HRHC ratios in July and August fell within 2–4 in many prefectures, whereas in September, the average and maximum HRHC ratios for all prefectures were 7.0 and 32.4, respectively. This difference can be related to the large difference in UTCImax between the maximum and minimum for a decade.

Comparative Analysis of the Antioxidative and Hepatoprotective Activities of Dimethyl Diphenyl Bicarboxylate in Four Animal Models of Hepatic Injury

As a well-known hepatoprotective and antioxidant agent, dimethyl diphenyl bicarboxylate (DDB) has frequently been employed to remedy various liver diseases. However, it is still uncertain whether DDB exerts consistent hepatoprotective and antioxidative activities against varying degrees of hepatic damage. Therefore, DDB (100, 25, 5, or 50 mg/kg depending on the model) was administered to animals in four representative models of liver injury (CCl4 chemical acute model, DMN subchronic model, TAA chronic model, and restraint stress psychological acute model). Horizontal comparative analysis indicated that DDB significantly lowered the excess serum AST and ALT levels in the CCl4 and DMN models but not in the TAA and restraint stress models. In accordance with this result, DDB markedly reduced oxidative stress indices (hepatic MDA and ROS) but restored five main antioxidant components (GSH content, GSH-peroxidase, GSH-reductase, SOD, and catalase activity) in the CCl4 and DMN models. DDB failed to normalize oxidative stressors in the restraint stress-induced injury model and restore these five antioxidant components in the TAA model. Overall, our results produced a comprehensive overview of the effects of DDB on oxidative stressors and the main antioxidative components using four animal models. These findings will provide valuable clues to guide therapeutic clinical applications.

Spatio-Temporal Distribution of Digitaria insularis: Risk Analysis of Areas with Potential for Selection of Glyphosate-Resistant Biotypes in Eucalyptus Crops in Brazil

The objective of this study was to model the spatio-temporal distribution of Digitaria insularis (D. insularis) and analyze the risk of selection of glyphosate-resistant biotypes in eucalyptus cultivation in Brazil. Global data on the distribution of the specie were collected and associated with their ideal growth characteristics. The models were generated using Climex software, providing a predictive modeling technique. Biological data, species distribution, and climatic parameters were used to predict and map potential areas for the species of interest through the combination of growth and stress indices, giving rise to the Ecoclimatic Index (EI). The spatial distribution of D. insularis is predominantly in South and Central America and southern North America. The model had a good fit with the collected data and predicted higher EI values for tropical and subtropical regions, as was the case in Brazil. Species growth can occur throughout the year, with lower rates in winter, mainly in the country’s southern regions. Brazil has high climatic suitability for the occurrence of Digitaria insularis. Due to the climate suitability evidenced by the models and the expressive use of the same active ingredient, there is a risk of selecting glyphosate-resistant Digitaria insularis biotypes in eucalyptus cultivation areas.