Reduced‐sodium Vienna sausage: Selected quality characteristics, optimized salt mixture, and commercial scale‐up production

Recombinant vaccines have been developed which are highly effective in preventing infection with Taenia ovis in sheep, Taenia saginata in cattle, Taenia solium in pigs and Echinococcus granulosus in livestock animals. T. ovis and T. saginata are economically significant parasites and the commercial success or otherwise of vaccines against them will rely on their economic value. E. granulosus and T. solium are zoonotic parasites that cause cystic hydatid disease and neurocysticercosis, respectively, in humans. Vaccines against these parasites have been developed to assist with the control of transmission of the human diseases rather than for prevention of infections in livestock per se. Regions of high prevalence for cystic hydatid disease and neurocysticercosis occur primarily in the developing world. As a consequence, vaccines against them are of little or no commercially interest – they are Orphan Vaccines. Lack of commercial interest in these vaccines has made public sector support for their development necessary well beyond the research phase trough into completion of commercial scale-up and other more commercially-related assessments. Practical use of the vaccines will require commercial-scale production according to international manufacturing standards. Identifying partners and support in this endeavour is now of prime importance in efforts to achieve the potential of these vaccines as new tools for the control of cystic hydatid disease and neurocysticercosis.

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Scale-up considerations: Pilot to commercial scale

10.1063/1.49363 ◽

1996 ◽

Author(s):

Dan Weisiger

Keyword(s):

Scale Up ◽

Commercial Scale

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Identifying and Sharing the Knowledge Required for Scaling Up Innovative Technologies in the Process Industry

International Journal of Innovation and Technology Management ◽

10.1142/s0219877017500067 ◽

2016 ◽

Vol 13 (06) ◽

pp. 1750006

Author(s):

Manjusha Thorpe ◽

Tom Ridgman

Keyword(s):

Knowledge Management ◽

Management Practices ◽

New Technologies ◽

Scale Up ◽

Scaling Up ◽

Process Industry ◽

Commercial Scale ◽

Unified View ◽

Knowledge Management Practices ◽

Manufacturing Technologies

The importance of developing innovative manufacturing technologies in the process industry is increasing in response to environmental concerns. However, scaling up new technologies from the laboratory to the commercial scale is problematic. A unified view on the challenges encountered during scale-up does not appear to exist in the literature. Nevertheless, there is recognition of knowledge gaps and a lack of approaches to knowledge management. This research identifies the knowledge required to carry out scale-up and appropriate knowledge management practices. The findings indicate that the required knowledge does exist to a large extent but that it is not effectively deployed.

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Survey on Production, Marketing and Consumption of Gundpak: A Traditional Khoa Based Milk Product of Nepal

Journal of Food Science and Technology Nepal ◽

10.3126/jfstn.v6i0.8259 ◽

2013 ◽

Vol 6 ◽

pp. 43-52

Author(s):

Pushipa Prasad Acharya ◽

Ganga Prasad Kharel ◽

Megharaj Bhandari

Keyword(s):

Shelf Life ◽

Process Optimization ◽

Quality Characteristics ◽

Ambient Condition ◽

Kathmandu Valley ◽

Chemical Compositions ◽

Milk Product ◽

Dried Fruits ◽

Commercial Scale ◽

Plastic Containers

This study aims to explore a traditional technology of Gundpak production, marketing and consumption in Nepal. The major ingredients used for Gundpak production are Khoa, sugar, ghee and gum, while minor ingredients are dried fruits, nuts, watermelon seeds, battisa powder, Jesthalangwadi etc. The annual production of Gundpak in Kathmandu valley has been estimated approximately 579.1MT and sales about 550.4MT with a worth of NRs. 192.5 million. Mainly, there are two varieties of Gundpak named as normal and medicinal. Majority of Gundpak producers sale their product in an open tray called Kisti. However, some manufacturers started to pack the product into plastic containers with varying sizes. The shelf-life may vary i.e. one week in summer and two weeks in winter at ambient condition. The market products were found inconsistent in chemical compositions and other quality characteristics. Therefore, there is an urgent need of process optimization as well as quality standardization of Gundpak production in commercial scale. J. Food Sci. Technol. Nepal, Vol. 6 (43-52), 2010 DOI: http://dx.doi.org/10.3126/jfstn.v6i0.8259

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Legacy Metal Fuel Data Exploration for Commercial Scale-Up

10.2172/1496023 ◽

2019 ◽

Author(s):

Abdellatif M. Yacout

Keyword(s):

Scale Up ◽

Data Exploration ◽

Commercial Scale ◽

Metal Fuel

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Commercial-Scale Visible-light Trifluoromethylation of 2-Chlorothiophenol using CF3I gas.

10.33774/chemrxiv-2021-z3xm8-v2 ◽

2021 ◽

Author(s):

Kaid Harper ◽

Timothy Grieme ◽

Timothy Towne ◽

Daniel Mack ◽

Moiz Diwan ◽

...

Keyword(s):

Visible Light ◽

Scale Up ◽

Plug Flow ◽

Stirred Tank ◽

Continuous Manufacturing ◽

Literature Report ◽

Fine Chemical ◽

Mechanistic Insight ◽

Commercial Scale ◽

Continuous Stirred Tank

Despite the growth of photoredox methods in academia, application of photoredox at scale in the pharmaceutical and fine chemical industries has been slow. In this report, a photoredox trifluoromethylation of a thiophenol was modified from the original literature report and the mechanism was investigated to define key scale-up parameters. The mechanistic insight was leveraged in the design and execution of two different reactor designs: an LED-based plug flow photoreactor as well as a laser-based continuous stirred tank photoreactor. In one of the first examples of commercial scale photoredox chemistry, the process was scaled to provide over 500 kilograms of the desired intermediate and amended to fully continuous manufacturing.

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Agrivoltaic Systems Design and Assessment: A Critical Review, and a Descriptive Model towards a Sustainable Landscape Vision (Three-Dimensional Agrivoltaic Patterns)

Sustainability ◽

10.3390/su13126871 ◽

2021 ◽

Vol 13 (12) ◽

pp. 6871

Author(s):

Carlos Toledo ◽

Alessandra Scognamiglio

Keyword(s):

Scale Up ◽

Three Dimensional ◽

Systems Design ◽

Energy Transition ◽

Well Being ◽

Ecological Impacts ◽

Spatial Design ◽

Commercial Scale ◽

Landscape Transformation ◽

And Performance

As an answer to the increasing demand for photovoltaics as a key element in the energy transition strategy of many countries—which entails land use issues, as well as concerns regarding landscape transformation, biodiversity, ecosystems and human well-being—new approaches and market segments have emerged that consider integrated perspectives. Among these, agrivoltaics is emerging as very promising for allowing benefits in the food–energy (and water) nexus. Demonstrative projects are developing worldwide, and experience with varied design solutions suitable for the scale up to commercial scale is being gathered based primarily on efficiency considerations; nevertheless, it is unquestionable that with the increase in the size, from the demonstration to the commercial scale, attention has to be paid to ecological impacts associated to specific design choices, and namely to those related to landscape transformation issues. This study reviews and analyzes the technological and spatial design options that have become available to date implementing a rigorous, comprehensive analysis based on the most updated knowledge in the field, and proposes a thorough methodology based on design and performance parameters that enable us to define the main attributes of the system from a trans-disciplinary perspective.

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