Effect of quercetin on cadmium chloride-induced impairments in sexual behaviour and steroidogenesis in male Wistar rats

Andrologia ◽  
2017 ◽  
Vol 50 (2) ◽  
pp. e12866 ◽  
Author(s):  
G. A. Ujah ◽  
V. U. Nna ◽  
M. I. Agah ◽  
L. O. Omue ◽  
C. B. Leku ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Cadmium Chloride ◽  
Wistar Rats ◽  
Male Wistar Rats

scholarly journals Effect of Hydroalcoholic Extract ofCydonia oblongaMiller (Quince) on Sexual Behaviour of Wistar Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Muhammad Aslam ◽  
Ali Akbar Sial
Keyword(s):  
Body Weight ◽  
Single Dose ◽  
Sexual Behaviour ◽  
Wistar Rats ◽  
Sexually Active ◽  
Cydonia Oblonga ◽  
Hydroalcoholic Extract ◽  
Male Wistar Rats ◽  
Mating Performance ◽  
Remarkable Manner

Cydonia oblongaMiller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits ofCydonia oblongaMiller (quince) in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantlyP<0.01. The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.

Evaluation of the Influence of Experimental Periodontitis on the Sexual Behaviour of Male Wistar Rats

2016 ◽  
Vol 15 (9) ◽  
pp. 1-8
Author(s):  
Stefany Pedrotti ◽  
Patricia Nassar ◽  
Sara Sagae ◽  
Karine Costa ◽  
Celia Beu ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Wistar Rats ◽  
Male Wistar Rats ◽  
Experimental Periodontitis

scholarly journals Effects of Garcinia hydroxybiflavanonol-1 (GB1) isolated from Garcinia kola Heckel (Guttiferae) seeds on reproductive toxicity induced with cadmium chloride (CdCl2) in male Wistar rats

2020 ◽  
Vol 4 (1) ◽  
pp. 21-30
Author(s):  
E. A. Uwagie-Ero ◽  
C. O. Nwaehujor
Keyword(s):  
Cadmium Chloride ◽  
Wistar Rats ◽  
Sperm Count ◽  
Cadmium Toxicity ◽  
Reproductive Toxicity ◽  
Seminiferous Tubules ◽  
Garcinia Kola ◽  
Male Wistar Rats ◽  
Garcinia Kola Heckel ◽  
Group B

To examine the effects of Garcinia hydroxybiflavanonol-1 (GB1) isolated from seeds of Garcinia kola Heckel (Guttiferae) on reproductive toxicity induced with cadmium chloride (CdCl2) in male Wistar rats. Rats were randomly assigned to Groups 1 to 3 (n = 12) as follows; A: control, B: CdCl2 only group, C: CdCl2+GB1. Cadmium toxicity was induced by including 2.5 mg/kg of CdCl2 into the rats’ drinking water and GB1 was dissolved in 0.5 % Tween20 and administered per os daily for 90 days. Four (4) animals from each group was humanely euthanized every 30 days. The testes were exteriorized and sperm cells collected from the caudal epididymis for analysis and histology.The result showed accumulation of Cadmium (Cd) in the testes of Wistar rats and a significant decrease (p< 0.05) in sperm count and sperm motility in Group B compared to Groups A and C. There was also a significant increase (p< 0.05) in immotile sperm count, headless sperm count and sluggish sperm count in Group B. Histology results revealed that CdCl2 significantly reduced the volume of spermatozoa in the seminiferous tubules and resulted in reduced spermatogenesis observed, in reduced number of sperm counts and histology. Amelioration with GB1 restored the testicles to normal spermatogenic activities after 90 days of treatment.

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