The preventive role of wheat germ oil against sertraline‐induced testicular damage in male albino rats

Andrologia ◽  
2019 ◽  
Vol 51 (10) ◽  
Author(s):  
Hamida Hamdi
Keyword(s):  
Wheat Germ ◽  
Albino Rats ◽  
Testicular Damage ◽  
Wheat Germ Oil ◽  
Preventive Role

scholarly journals The Protective Role of Wheat Germ Oil Against Adverse Effect of Deltamethrin on Reproductive Aspects of Male Albino Rats

2021 ◽  
Vol 6 (3) ◽  
pp. 70-75
Author(s):  
Abeer M. Radi ◽  
Naglaa Abdel-Azeem ◽  
Ismail Mostafa ◽  
Nermeen Helmy ◽  
Walaa Ahmed
Keyword(s):  
Adverse Effect ◽  
Wheat Germ ◽  
Protective Role ◽  
Albino Rats ◽  
Wheat Germ Oil

HOST SELECTION BY THE ADULT CABBAGE MAGGOT, HYLEMYA BRASSICAE (DIPTERA: ANTHOMYIIDAE): EFFECT OF GLUCOSINOLATES AND COMMON NUTRIENTS ON OVIPOSITION

1976 ◽  
Vol 108 (10) ◽  
pp. 1021-1030 ◽  
Author(s):  
K. S. S. Nair ◽  
F. L. McEwen
Keyword(s):  
Host Selection ◽  
Plant Material ◽  
Wheat Germ ◽  
Casein Hydrolysate ◽  
Allyl Isothiocyanate ◽  
Mustard Oil ◽  
Wheat Germ Oil ◽  
Hylemya Brassicae ◽  
Cabbage Maggot

AbstractIn Hylemya brassicae (Bouché) little oviposition occurred when access to host plant material was denied. The mustard oil, allyl isothiocyanate (AITC), stimulated the flies into greater activity and attracted them to its source. Sinigrin and four other glucosinolates (mustard oil glucosides) tested induced oviposition. AITC by itself did not induce, oviposition, but in the presence of a glucosinolate, small concentrations of AITC caused an increase in the number of eggs laid. Glucose, sucrose, casein, wheat germ oil, and a mixture of B-vitamins did not influence oviposition at the concentrations tested, but casein hydrolysate inhibited it. The role of glucosinolates and common nutrients in host selection by H. brassicae is discussed.

Pregabalin induced reproductive toxicity and body weight changes by affecting caspase3 and leptin expression: Protective role of wheat germ oil

Life Sciences ◽  
2020 ◽  
Vol 260 ◽  
pp. 118344
Author(s):  
Dina A. Shokry ◽  
Naglaa El Nabrawy ◽  
Hanan D. Yassa ◽  
Shereen S. Gaber ◽  
Gaber El-Saber Batiha ◽  
...  
Keyword(s):  
Body Weight ◽  
Wheat Germ ◽  
Reproductive Toxicity ◽  
Protective Role ◽  
Weight Changes ◽  
Wheat Germ Oil ◽  
Body Weight Changes ◽  
Leptin Expression

EFFECT OF ETHANOLIC EXTRACT FRACTIONS OF ROSA CENTIFOLIA IN DOXORUBICIN-INDUCED MYOCARDIAL TOXICITY IN ALBINO RATS

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (12) ◽  
pp. 27-33
Author(s):  
S. K Nimbal ◽  
◽  
B. C Koti
Keyword(s):  
Ethyl Acetate ◽  
Biochemical Parameters ◽  
Troponin I ◽  
Ethanolic Extract ◽  
Ethyl Acetate Fraction ◽  
Repeated Administration ◽  
Albino Rats ◽  
Standard Drug ◽  
Preventive Role

This study was undertaken to understand the preventive role of ethanolic extract fractions of flower petals of Rosa centifolia (RC) against Doxorubicin-induced myocardial toxicity in albino rats. The ethanolic extract of flower petals of RC was prepared by hot extraction method and further fractionated into petroleum ether (PERC), chloroform (CHRC), ethyl acetate (EARC) and aqueous (AQRC) fractions by increasing in order of polarity. Cardiotoxicity was produced by cumulative administration of Dox (2.5 mg/kg alternative day for two weeks). All four fractions (PERC-20 mg/kg, CLRC-15 mg/kg, EARC-40 mg/kg and AQRC-25 mg/kg) were administered as pretreatment for two weeks followed by Dox on alternative days for two weeks. The general observations, biomarker enzymes like lactate dehydrogenase (LDH), creatine kinase (CK-MB) and troponin-I (cTnI), biochemical parameters such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were monitored after three weeks of last dose. Myocardial toxicity was also evaluated by histopathologic studies. Repeated administration of Dox-induced cardiomyopathy was characterized with an increased level of biomarkers and antioxidant deficit. Pretreatment with the EARC (40 mg/kg) and standard drug (Vit-E 100 mg/kg) significantly protected myocardium from the toxic effects of Dox by reducing the elevated level of biomarker enzymes like LDH, CK-MB, biochemical parameters such as AST and ALT, absence of cTnI and restoring of disorganized myocardial tissue to normal. The biomarker, biochemical and histopathological data evidently substantiate the cardioprotective effect of EARC, which could be attributed to flavanoids present in the ethyl acetate fraction.

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