Ultrasonic testicular size of 24,440 adult Vietnamese men and the correlation with age and hormonal profiles

Andrologia ◽  
2021 ◽  
Author(s):  
Bac Nguyen Hoai ◽  
Long Hoang ◽  
Duc Tran ◽  
Thang Nguyen Cao ◽  
Luu Doan Tien ◽  
...  
Keyword(s):  
Hormonal Profiles ◽  
Testicular Size

scholarly journals Developmental Hormonal Profiles in rdw Rats with Congenital Hypothyroidism Accompanying Increased Testicular Size and Infertility in Adulthood

2004 ◽  
Vol 50 (6) ◽  
pp. 675-684 ◽  
Author(s):  
Motoaki UMEZU ◽  
Satoshi KAGABU ◽  
Jiany Y. JIANG ◽  
Sueo NIIMURA ◽  
Eimei SATO
Keyword(s):  
Congenital Hypothyroidism ◽  
Hormonal Profiles ◽  
Testicular Size

Developmental hormonal profiles accompanying the neonatal hypothyroidism-induced increase in adult testicular size and sperm production in the rat.

Endocrinology ◽  
1992 ◽  
Vol 131 (2) ◽  
pp. 559-565
Author(s):  
J D Kirby ◽  
A E Jetton ◽  
P S Cooke ◽  
R A Hess ◽  
D Bunick ◽  
...  
Keyword(s):  
Sperm Production ◽  
Neonatal Hypothyroidism ◽  
Hormonal Profiles ◽  
Testicular Size

1587: Correlation of Testicular Size on Physical Examination with Pathologic Findings on Testicular Biopsy

2004 ◽  
Vol 171 (4S) ◽  
pp. 420-420
Author(s):  
Brian R. Matlaga ◽  
Dennis J. Kubinski ◽  
Dominick J. Carbone
Keyword(s):  
Physical Examination ◽  
Testicular Biopsy ◽  
Pathologic Findings ◽  
Testicular Size

ROLE OF THE THYROID GLAND IN DEVELOPMENT AND MAINTENANCE OF RENAL HYPERTENSION IN RATS

1960 ◽  
Vol XXXIV (III) ◽  
pp. 411-429 ◽  
Author(s):  
Melvin J. Fregly ◽  
Kenneth M. Cook
Keyword(s):  
Blood Pressure ◽  
Rate Increase ◽  
Renal Hypertension ◽  
The Other ◽  
Elevated Blood Pressure ◽  
Unit Weight ◽  
Elevated Blood ◽  
Inhibition Of Growth ◽  
Testicular Size

ABSTRACT The anti-thyroid drugs, thiouracil, propylthiouracil, and methimazole, prevented both development of elevated blood pressure and cardiac hypertrophy usually accompanying kidney encapsulation with latex envelopes. These drugs also reduced elevated blood pressure of rats with hypertension of 13 to 40 weeks' duration prior to drug administration. Addition of desiccated thyroid powder to diet containing an anti-thyroid drug overcame the anti-hypertensive effect of the latter. Withdrawal of thyroid powder only was followed by return of blood pressure to previous low level within 3 weeks. The results suggest that the anti-hypertensive effect of these drugs is related directly to the hypothyroidism produced rather than to extrathyroidal effects of the drugs. Comparison of potencies of the 3 drugs in terms of anti-hypertensive effect, inhibition of growth rate, increase in testicular size, and increase in thyroid size suggests that propylthiouracil and methimazole are equally potent per unit weight of drug. Thiouracil has approximately half the potency of the other two.

Nonlinear models to describe the testicular size growth curve of Mangalarga Marchador stallions

2021 ◽  
pp. 103422
Author(s):  
Danielle Estanislau Coelho Silva ◽  
Jurandy Mauro Penitente-Filho ◽  
Domingos Lollobrigida Souza Neto ◽  
Bruna Waddington ◽  
Renan Reis de Oliveira ◽  
...  
Keyword(s):  
Growth Curve ◽  
Nonlinear Models ◽  
Size Growth ◽  
Testicular Size

scholarly journals Nonylphenol Induces Apoptosis through ROS/JNK Signaling in a Spermatogonia Cell Line

2020 ◽  
Vol 22 (1) ◽  
pp. 307
Author(s):  
Hyun-Jung Park ◽  
Ran Lee ◽  
Hyunjin Yoo ◽  
Kwonho Hong ◽  
Hyuk Song
Keyword(s):  
Molecular Mechanisms ◽  
Mapk Signaling ◽  
Ros Generation ◽  
Dependent Manner ◽  
Jnk Signaling ◽  
Apoptosis Markers ◽  
Testicular Size ◽  
Spermatogonia Cell ◽  
Induced Apoptosis ◽  
Dose Dependent

Nonylphenol (NP) is an endocrine-disruptor chemical that negatively affects reproductive health. Testes exposure to NP results in testicular structure disruption and a reduction in testicular size and testosterone levels. However, the effects of NP on spermatogonia in testes have not been fully elucidated. In this study, the molecular mechanisms of NP in GC-1 spermatogonia (spg) cells were investigated. We found that cell viability significantly decreased and apoptosis increased in a dose-dependent manner when GC-1 spg cells were exposed to NP. Furthermore, the expression levels of the pro-apoptotic proteins increased, whereas anti-apoptosis markers decreased in NP-exposed GC-1 spg cells. We also found that NP increased reactive oxygen species (ROS) generation, suggesting that ROS-induced activation of the MAPK signaling pathway is the molecular mechanism of NP-induced apoptosis in GC-1 spg cells. Thus, NP could induce c-Jun phosphorylation; dose-dependent expression of JNK, MKK4, p53, and p38; and the subsequent inhibition of ERK1/2 and MEK1/2 phosphorylation. The genes involved in apoptosis and JNK signaling were also upregulated in GC-1 spg cells treated with NP compared to those in the controls. Our findings suggest that NP induces apoptosis through ROS/JNK signaling in GC-1 spg cells.

Influence of N-methyl-d-aspartate on the reproductive axis of male Syrian hamsters

1993 ◽  
Vol 137 (2) ◽  
pp. 247-NP ◽  
Author(s):  
H. F. Urbanski ◽  
M. M. Fahy ◽  
P. M. Collins
Keyword(s):  
Hormone Secretion ◽  
Serum Testosterone ◽  
Inhibitory Effect ◽  
Stimulatory Action ◽  
Syrian Hamsters ◽  
Reproductive Axis ◽  
Treatment Paradigm ◽  
Testicular Size ◽  
Lh Releasing Hormone

ABSTRACT The influence of excitatory amino acids (EAAs) on reproductive neuroendocrine function was investigated in adult male Syrian hamsters of the LSH/Ss Lak strain. Before the study, the animals were maintained in a sexually regressed condition, under short days (SD) and subsequently were either transferred to long days (LD) or kept under SD, for a further 4 weeks. In the former group, photostimulation produced a predictable elevation in the hypophysial contents and serum concentrations of FSH and LH. This was accompanied by an increase in testicular size, an elevation in serum testosterone levels and an increase in spermatogenic activity; the SD hamsters remained sexually quiescent throughout the study. In contrast, SD hamsters that were given daily injections of the EAA agonist, N-methyl-d,l-aspartate (NMA: 50 mg/kg body weight, s.c.), showed stimulatory responses that were generally even more pronounced than those shown by the LD group. Surprisingly, an identical NMA treatment paradigm failed to cause a similar activation of the reproductive axis in LD hamsters that were given daily afternoon injections of melatonin (25 μg, s.c), even though the inhibitory effect of this melatonin treatment is generally regarded as being comparable with that produced by exposure to SD. Although EAAs can acutely stimulate the neurocircuitry that controls LH-releasing hormone secretion, the present findings suggest that EAAs might also exert a long-term stimulatory action by acting further upstream in the photoneuroendocrine pathway. Journal of Endocrinology (1993) 137, 247–252

The Effects of Stressful Broodstock Handling on Hormonal Profiles and Reproductive Performance ofRhamdia quelen(Quoy & Gaimard) Females

2008 ◽  
Vol 39 (6) ◽  
pp. 835-841 ◽  
Author(s):  
Auren Benk Soso ◽  
Leonardo José Gil Barcellos ◽  
Maria José Ranzani-Paiva ◽  
Luiz Carlos Kreutz ◽  
Rosmari Mezzalira Quevedo ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
Hormonal Profiles
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