Hidden cause of intestinal bleeding from jejunal diverticulum revealed on enteroscopy and treated successfully with segmental resection

2021 ◽  
Author(s):  
Noor Tilawatu Kamaruddin ◽  
Jih Huei Tan ◽  
Jin Zhe Teh
Keyword(s):  
Segmental Resection ◽  
Intestinal Bleeding ◽  
Jejunal Diverticulum

scholarly journals 1228 Massive Gastrointestinal Bleeding Secondary to Bleeding Jejunal Diverticulum

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
A. Mukhtar A Mukhtar ◽  
B.A. Abdalaziz Alshareif ◽  
M. Gareeballah Yousif Hijazi ◽  
M Y Ibrahim
Keyword(s):  
Histopathological Examination ◽  
Primary Anastomosis ◽  
Exploratory Laparotomy ◽  
Intestinal Bleeding ◽  
Upper Gastrointestinal Endoscopy ◽  
Jejunal Diverticulum ◽  
Massive Gastrointestinal Bleeding ◽  
Blood Clots ◽  
Lower Endoscopy ◽  
Upper Gastrointestinal

Abstract Usually, the Jejunal diverticula appeared multiple and vary in size. These false diverticula lack the muscular coat of the normal intestinal walls, and most patients presented with it were asymptomatic. Although 10% of all patients develop complications such as perforation, obstruction, or bleeding, which then requires surgical intervention, but bleeding is relatively rare among these complications. A case of 74 years old lady was referred to our hospital because of persistent hematemesis and fresh melena. Her previous and recent upper gastrointestinal endoscopy both revealed only gastric erosions without any active bleeding. Also, previous, and recent colonoscopy was done but not completed due to the presents of fresh blood and blood clots along the colon, which led to improper visualization. Her selective mesenteric angiography was done together with upper and lower endoscopy, but none of them revealed the source of bleeding. Emergency exploratory laparotomy was undertaken, and a prominent single jejunal diverticulum with a prominent vessel entering it was noted, and no bleeding from other sites detected. Enterotomy was performed, and enteroscopy confirmed ulceration at the jejunal diverticulum site. Resection of the portion containing the diverticulum and primary anastomosis was done, and this cured the patient. The histopathological examination of the specimen showed an ulcerative lesion with an exposed vessel suggestive of the source of bleeding. Although jejunal diverticula incidence is rare, it is important to look for such lesions in patients with intestinal bleeding. Keywords: jejunal diverticulum, small intestine, intestinal bleeding.

Segmental Resection and Replantation for Primary Malignant or Aggressive Tumors of the Upper Limb

2006 ◽  
Vol 22 (03) ◽  
Author(s):  
Soo Hahn ◽  
Sung Kim ◽  
Ho Kang ◽  
Kyoo Shin
Keyword(s):  
Upper Limb ◽  
Segmental Resection ◽  
Aggressive Tumors

The Usefulness of MDCT in Acute Intestinal Bleeding

2006 ◽  
Vol 55 (4) ◽  
pp. 381
Author(s):  
Kum Rae Kim ◽  
Won Kyu Park ◽  
Jae Woon Kim ◽  
Jay Chun Chang ◽  
Han Won Jang
Keyword(s):  
Intestinal Bleeding

Oral kyuki‐kyogai‐to (KKT) for intestinal bleeding in Fontan‐associated protein‐losing enteropathy

2019 ◽  
Vol 61 (9) ◽  
pp. 935-937 ◽  
Author(s):  
Kazuhiro Takahashi ◽  
Kenzo Sakurai ◽  
Kiyotaka Takefuta ◽  
Mami Nakayashiro
Keyword(s):  
Intestinal Bleeding ◽  
Protein Losing Enteropathy

scholarly journals Microencapsulated Bifidobacterium bifidum and Lactobacillus gasseri in Combination with Quercetin Inhibit Colorectal Cancer Development in ApcMin/+ Mice

2021 ◽  
Vol 22 (9) ◽  
pp. 4906
Author(s):  
Iván Benito ◽  
Ignacio J. Encío ◽  
Fermín I. Milagro ◽  
María Alfaro ◽  
Ana Martínez-Peñuela ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Body Weight Loss ◽  
Dietary Supplementation ◽  
Bifidobacterium Bifidum ◽  
Aberrant Crypt Foci ◽  
Intestinal Bleeding ◽  
Standard Diet ◽  
Colon Tissue ◽  
Lactobacillus Gasseri ◽  
Reduced Body

Recent studies have suggested that flavonoids such as quercetin and probiotics such as Bifidobacterium bifidum (Bf) and Lactobacillus gasseri (Lg) could play a relevant role in inhibiting colon cancer cell growth. Our study investigated the role of dietary supplementation with microencapsulated probiotics (Bf and Lg) along with quercetin in the development of mouse colorectal cancer (CRC). Methods: Adenomatous polyposis coli/multiple intestinal neoplasia (ApcMin/+) mice were fed a standard diet or the same diet supplemented with microencapsulated probiotics (Bf and Lg strains, 107 CFU/100 g food) or both probiotics strains plus microencapsulated quercetin (15 mg/100 g food) for 73 days. Changes in body and organ weights, energy metabolism, intestinal microbiota, and colon tissue were determined. The expression of genes related to the Wnt pathway was also analyzed in colon samples. Results: Dietary supplementation with microencapsulated probiotics or microencapsulated probiotics plus quercetin reduced body weight loss and intestinal bleeding in ApcMin/+ mice. An improvement in energy expenditure was observed after 8 weeks but not after 10 weeks of treatment. A supplemented diet with microencapsulated Bf and Lg reduced the number of aberrant crypt foci (ACF) and adenomas by 45% and 60%, respectively, whereas the supplementation with Bf, Lg and quercetin decreased the number of ACF and adenomas by 57% and 80%, respectively. Microencapsulated Bf and Lg in combination with quercetin could exert inhibition of the canonical Wnt/β-catenin signaling pathway in the colon of ApcMin/+ mice Conclusions: The administration of microencapsulated Bf and Lg, individually or in combination with quercetin, inhibits the CRC development in ApcMin/+ mice.

scholarly journals Longitudinal Microbiome Analysis in a Dextran Sulfate Sodium-Induced Colitis Mouse Model

2021 ◽  
Vol 9 (2) ◽  
pp. 370
Author(s):  
Hyunjoon Park ◽  
Soyoung Yeo ◽  
Seokwon Kang ◽  
Chul Sung Huh
Keyword(s):  
Mouse Model ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Intestinal Bleeding ◽  
Cross Sectional ◽  
Microbiome Analysis ◽  
Inflammatory Bowel ◽  
Factor Design ◽  
The Individual

The role of the gut microbiota in the pathogenesis of inflammatory bowel disease (IBD) has been in focus for decades. Although metagenomic observations in patients/animal colitis models have been attempted, the microbiome results were still indefinite and broad taxonomic presumptions were made due to the cross-sectional studies. Herein, we conducted a longitudinal microbiome analysis in a dextran sulfate sodium (DSS)-induced colitis mouse model with a two-factor design based on serial DSS dose (0, 1, 2, and 3%) and duration for 12 days, and four mice from each group were sacrificed at two-day intervals. During the colitis development, a transition of the cecal microbial diversity from the normal state to dysbiosis and dynamic changes of the populations were observed. We identified genera that significantly induced or depleted depending on DSS exposure, and confirmed the correlations of the individual taxa to the colitis severity indicated by inflammatory biomarkers (intestinal bleeding and neutrophil-derived indicators). Of note, each taxonomic population showed its own susceptibility to the changing colitis status. Our findings suggest that an understanding of the individual susceptibility to colitis conditions may contribute to identifying the role of the gut microbes in the pathogenesis of IBD.

scholarly journals Bile duct segmental resection versus pancreatoduodenectomy for middle and distal common bile duct cancer

2018 ◽  
Vol 94 (5) ◽  
pp. 240 ◽  
Author(s):  
Naru Kim ◽  
Huisong Lee ◽  
Seog Ki Min ◽  
Hyeon Kook Lee
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Bile Duct Cancer ◽  
Segmental Resection ◽  
Distal Common Bile Duct ◽  
Common Bile Duct Cancer ◽  
Duct Cancer

Distraction osteogenesis for reconstruction after mandibular segmental resection

2002 ◽  
Vol 93 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Tetsu Takahashi ◽  
Masayuki Fukuda ◽  
Takahiro Aiba ◽  
Katsuyuki Funaki ◽  
Takayoshi Ohnuki ◽  
...  
Keyword(s):  
Distraction Osteogenesis ◽  
Segmental Resection

Image Distortion Due to Massive Ascites during Tc-99m RBC Scanning for Intestinal Bleeding

1993 ◽  
Vol 18 (6) ◽  
pp. 520-521
Author(s):  
SARAH K. CONWAY ◽  
RUSSELL C. BRIGGS
Keyword(s):  
Image Distortion ◽  
Intestinal Bleeding ◽  
Massive Ascites
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