Oral kyuki‐kyogai‐to (KKT) for intestinal bleeding in Fontan‐associated protein‐losing enteropathy

2019 ◽  
Vol 61 (9) ◽  
pp. 935-937 ◽  
Author(s):  
Kazuhiro Takahashi ◽  
Kenzo Sakurai ◽  
Kiyotaka Takefuta ◽  
Mami Nakayashiro
Keyword(s):  
Intestinal Bleeding ◽  
Protein Losing Enteropathy

Management of Disseminated Intra-abdominal Lymphangiomatosis With Protein-Losing Enteropathy and Intestinal Bleeding

1995 ◽  
Vol 88 (11) ◽  
pp. 1156-1158 ◽  
Author(s):  
AKIYOSHITAKAMI ◽  
SHINJINAKAO ◽  
NAOMI SUGIMORI ◽  
FUMIO ISHIDA ◽  
MASAHIDE YAMAZAKI ◽  
...  
Keyword(s):  
Intestinal Bleeding ◽  
Protein Losing Enteropathy

Protein-losing Enteropathy and Intestinal Bleeding

1966 ◽  
Vol 64 (3) ◽  
pp. 628 ◽  
Author(s):  
JOHN D. DAVIDSON
Keyword(s):  
Intestinal Bleeding ◽  
Protein Losing Enteropathy

FÆCAL EXCRETION OF α1-ANTITRYPSIN IN PROTEIN-LOSING ENTEROPATHY

The Lancet ◽  
1980 ◽  
Vol 315 (8167) ◽  
pp. 711
Author(s):  
N Keaney
Keyword(s):  
Protein Losing Enteropathy ◽  
Faecal Excretion

The Usefulness of MDCT in Acute Intestinal Bleeding

2006 ◽  
Vol 55 (4) ◽  
pp. 381
Author(s):  
Kum Rae Kim ◽  
Won Kyu Park ◽  
Jae Woon Kim ◽  
Jay Chun Chang ◽  
Han Won Jang
Keyword(s):  
Intestinal Bleeding

scholarly journals Microencapsulated Bifidobacterium bifidum and Lactobacillus gasseri in Combination with Quercetin Inhibit Colorectal Cancer Development in ApcMin/+ Mice

2021 ◽  
Vol 22 (9) ◽  
pp. 4906
Author(s):  
Iván Benito ◽  
Ignacio J. Encío ◽  
Fermín I. Milagro ◽  
María Alfaro ◽  
Ana Martínez-Peñuela ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Body Weight Loss ◽  
Dietary Supplementation ◽  
Bifidobacterium Bifidum ◽  
Aberrant Crypt Foci ◽  
Intestinal Bleeding ◽  
Standard Diet ◽  
Colon Tissue ◽  
Lactobacillus Gasseri ◽  
Reduced Body

Recent studies have suggested that flavonoids such as quercetin and probiotics such as Bifidobacterium bifidum (Bf) and Lactobacillus gasseri (Lg) could play a relevant role in inhibiting colon cancer cell growth. Our study investigated the role of dietary supplementation with microencapsulated probiotics (Bf and Lg) along with quercetin in the development of mouse colorectal cancer (CRC). Methods: Adenomatous polyposis coli/multiple intestinal neoplasia (ApcMin/+) mice were fed a standard diet or the same diet supplemented with microencapsulated probiotics (Bf and Lg strains, 107 CFU/100 g food) or both probiotics strains plus microencapsulated quercetin (15 mg/100 g food) for 73 days. Changes in body and organ weights, energy metabolism, intestinal microbiota, and colon tissue were determined. The expression of genes related to the Wnt pathway was also analyzed in colon samples. Results: Dietary supplementation with microencapsulated probiotics or microencapsulated probiotics plus quercetin reduced body weight loss and intestinal bleeding in ApcMin/+ mice. An improvement in energy expenditure was observed after 8 weeks but not after 10 weeks of treatment. A supplemented diet with microencapsulated Bf and Lg reduced the number of aberrant crypt foci (ACF) and adenomas by 45% and 60%, respectively, whereas the supplementation with Bf, Lg and quercetin decreased the number of ACF and adenomas by 57% and 80%, respectively. Microencapsulated Bf and Lg in combination with quercetin could exert inhibition of the canonical Wnt/β-catenin signaling pathway in the colon of ApcMin/+ mice Conclusions: The administration of microencapsulated Bf and Lg, individually or in combination with quercetin, inhibits the CRC development in ApcMin/+ mice.

scholarly journals Protein-losing enteropathy

1966 ◽  
Vol 50 (3) ◽  
pp. 422-443 ◽  
Author(s):  
Thomas A. Waldmann
Keyword(s):  
Protein Losing Enteropathy

scholarly journals Longitudinal Microbiome Analysis in a Dextran Sulfate Sodium-Induced Colitis Mouse Model

2021 ◽  
Vol 9 (2) ◽  
pp. 370
Author(s):  
Hyunjoon Park ◽  
Soyoung Yeo ◽  
Seokwon Kang ◽  
Chul Sung Huh
Keyword(s):  
Mouse Model ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Intestinal Bleeding ◽  
Cross Sectional ◽  
Microbiome Analysis ◽  
Inflammatory Bowel ◽  
Factor Design ◽  
The Individual

The role of the gut microbiota in the pathogenesis of inflammatory bowel disease (IBD) has been in focus for decades. Although metagenomic observations in patients/animal colitis models have been attempted, the microbiome results were still indefinite and broad taxonomic presumptions were made due to the cross-sectional studies. Herein, we conducted a longitudinal microbiome analysis in a dextran sulfate sodium (DSS)-induced colitis mouse model with a two-factor design based on serial DSS dose (0, 1, 2, and 3%) and duration for 12 days, and four mice from each group were sacrificed at two-day intervals. During the colitis development, a transition of the cecal microbial diversity from the normal state to dysbiosis and dynamic changes of the populations were observed. We identified genera that significantly induced or depleted depending on DSS exposure, and confirmed the correlations of the individual taxa to the colitis severity indicated by inflammatory biomarkers (intestinal bleeding and neutrophil-derived indicators). Of note, each taxonomic population showed its own susceptibility to the changing colitis status. Our findings suggest that an understanding of the individual susceptibility to colitis conditions may contribute to identifying the role of the gut microbes in the pathogenesis of IBD.

scholarly journals The Consequence of Excessive Consumption of Cow’s Milk: Protein-Losing Enteropathy with Anasarca in the Course of Iron Deficiency Anemia—Case Reports and a Literature Review

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 828
Author(s):  
Karolina Graczykowska ◽  
Joanna Kaczmarek ◽  
Dominika Wilczyńska ◽  
Ewa Łoś-Rycharska ◽  
Aneta Krogulska
Keyword(s):  
Iron Deficiency ◽  
Literature Review ◽  
Iron Deficiency Anemia ◽  
Case Reports ◽  
Deficiency Anemia ◽  
Cow’S Milk ◽  
Milk Consumption ◽  
Protein Losing Enteropathy ◽  
Cow's Milk ◽  
Excessive Consumption

Cow’s milk is a key component of a child’s diet. While the consumption of even trace amounts can result in allergy to its proteins and/or hypolactasia, excessive cow’s milk consumption can result in numerous health complications, including iron deficiency, due to the diet being improperly balanced. Although the incidence of iron deficiency has declined, it remains the most widespread nutritional deficiency globally and the most common cause of anemia. One rare consequence of anemia caused by iron deficiency is protein-losing enteropathy; however, the mechanisms of its development are unclear. The following manuscript, based on a literature review, presents two rare cases of children, a 16-month-old boy and a 2.5-year-old girl, who developed severe microcytic anemia, enteropathy with hypoalbuminemia, and anasarca as a result of excessive cow’s milk consumption. It highlights the possible relationship between excessive consumption of cow’s milk in children and severe iron deficiency anemia with accompanying hypoalbuminemia; it may also result in serious clinical conditions, even in children that do not demonstrate food hypersensitivity.

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