Acquired Von Willebrand Syndrome and Blood Pump Design

2018 ◽  
Vol 42 (12) ◽  
pp. 1119-1124 ◽  
Author(s):  
Gerson Rosenberg ◽  
Christopher A. Siedlecki ◽  
Choon-Sik Jhun ◽  
William J. Weiss ◽  
Keefe Manning ◽  
...  
Keyword(s):  
Blood Pump ◽  
Pump Design ◽  
Acquired Von Willebrand Syndrome ◽  
Von Willebrand

Pathogenesis of antibody-induced acquired von willebrand syndrome

1980 ◽  
Vol 9 (4) ◽  
pp. 363-371 ◽  
Author(s):  
Tong Eng Gan ◽  
Ronald J. Sawers ◽  
Jerry Koutts
Keyword(s):  
Acquired Von Willebrand Syndrome ◽  
Von Willebrand

Acquired von Willebrand Syndrome in Systemic Lupus Erythematodes

2001 ◽  
Vol 7 (2) ◽  
pp. 106-112 ◽  
Author(s):  
Jan Jacques Michiels ◽  
Wilfried Schroyens ◽  
Marc van der Planken ◽  
Zwi Bememan
Keyword(s):  
Lupus Erythematodes ◽  
Systemic Lupus ◽  
Acquired Von Willebrand Syndrome ◽  
Systemic Lupus Erythematodes ◽  
Von Willebrand

Hemolysis generation from a novel, linear positive displacement blood pump for cardiopulmonary bypass on a six kilogram piglet: a preliminary report

Perfusion ◽  
2016 ◽  
Vol 32 (4) ◽  
pp. 264-268
Author(s):  
D. Scott Lawson ◽  
Derek Eilers ◽  
Suzanne Osorio Lujan ◽  
Maria Bortot ◽  
James Jaggers
Keyword(s):  
Cardiopulmonary Bypass ◽  
Surface Area ◽  
Preliminary Report ◽  
Blood Pump ◽  
Centrifugal Pumps ◽  
Clinical Value ◽  
Pump Design ◽  
Positive Displacement ◽  
Blood Pumps ◽  
Extracorporeal Circuits

Background: Current blood pumps used for cardiopulmonary bypass generally fall into two different pump design categories; non-occlusive centrifugal pumps and occlusive, positive-displacement roller pumps. The amount of foreign surface area of extracorporeal circuits correlates with post-operative morbidity due to systemic inflammation, leading to a push for technology that reduces the amount of foreign surfaces. Current roller pumps are bulky and the tubing forms an arc in the pumping chamber (raceway), positioning the inlet 360 degrees from the outlet, making it very difficult to place the pump closer to the patient and to efficiently reduce tubing length. These challenges put existing roller pumps at a disadvantage for use in a compact cardiopulmonary bypass circuit. Centrifugal blood pumps are easier to incorporate into miniature circuit designs. However, the prime volumes of current centrifugal pump designs are large, especially for pediatric extracorporeal circuits where the prime volumes are too great to be of clinical value. Method: We describe a preliminary report on a novel, occlusive, linear, single-helix, positive-displacement blood pump which allows for decreased prime volume and surface area of the extracorporeal circuit. This new experimental pump design was used to perfuse a 6 kilogram piglet with a pediatric cardiopulmonary bypass circuit for two hours of continuous use. Blood samples were obtained every thirty minutes and assayed for plasma free hemolysis generation. Conclusions: The results from this initial experiment showed low plasma free hemoglobin generation and encourages the authors to further develop this concept.

Bleeding diathesis associated with acquired von Willebrand Syndrome in three patients with chronic lymphocytic leukemia

2015 ◽  
Vol 56 (12) ◽  
pp. 3452-3454 ◽  
Author(s):  
Mona Lisa Alattar ◽  
Maria Ciccone ◽  
Mahmoud R. Gaballa ◽  
Candida Vitale ◽  
Xavier C. Badoux ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Bleeding Diathesis ◽  
Acquired Von Willebrand Syndrome ◽  
Von Willebrand

Intravenous immunoglobulin in patients with acquired Von Willebrand syndrome: A single referral centre experience

Haemophilia ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. e42-e45
Author(s):  
Julien Bertolino ◽  
Manal Ibrahim ◽  
Julie Seguier ◽  
Elodie Masson ◽  
Emmanuelle Bernit ◽  
...  
Keyword(s):  
Intravenous Immunoglobulin ◽  
Referral Centre ◽  
Acquired Von Willebrand Syndrome ◽  
Von Willebrand
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