The Association Between Adverse Childhood Experiences and Child Telomere Length: Examining Self‐Regulation as a Behavioral Mediator

2020 ◽  
Author(s):  
David W. Sosnowski ◽  
Wendy Kliewer ◽  
Cecelia R. Valrie ◽  
Marcia A. Winter ◽  
Zewelanji Serpell ◽  
...  
2013 ◽  
Vol 28 (3) ◽  
pp. 513-530 ◽  
Author(s):  
Rachael M. Swopes ◽  
Daniel V. Simonet ◽  
Anna E. Jaffe ◽  
Robert P. Tett ◽  
Joanne L. Davis

Intimate partner violence (IPV) has been linked to childhood abuse, posttraumatic stress disorder (PTSD), and low emotional intelligence (EI). Relationships among adverse childhood experiences (ACE), PTSD symptoms, and partner aggression (i.e., generalized tendency to aggress toward one’s partner) were assessed in 108 male IPV offenders. It was hypothesized that ACE is positively correlated with partner aggression, PTSD mediates the ACE-aggression relationship, and the ACE-PTSD-aggression mediation varies by selected EI facets. Results indicate that ACE has an indirect effect on partner aggression via PTSD and PTSD mediates the ACE–aggression link when emotional self-regulation is low and when intuition (vs. reason) is high. Trauma-exposed IPV offenders may benefit from comprehensive treatments focusing on PTSD symptoms, emotional control, and reasoning skills to reduce aggression.


2019 ◽  
Vol 13 ◽  
Author(s):  
David Bürgin ◽  
Aoife O'Donovan ◽  
Delfine d'Huart ◽  
Alain di Gallo ◽  
Anne Eckert ◽  
...  

2019 ◽  
Vol 29 (10) ◽  
pp. 1329-1338 ◽  
Author(s):  
Jason Lang ◽  
Judith McKie ◽  
Helen Smith ◽  
Angela McLaughlin ◽  
Christopher Gillberg ◽  
...  

Abstract A systematic review following PRISMA guidelines was conducted to answer the question: What epigenetic, telomeric and associated biological changes are associated with exposure to adverse childhood experiences (ACEs) in the under 12s? Using PRISMA guidelines, appropriate databases were searched. 190 papers were returned with 38 articles fully reviewed. Articles were each independently quality rated by two authors using the Crowe Critical Appraisal Tool and data were extracted. Of the 38 articles, 23 were rated as very high quality. Most study participants were adults (n = 7769) with n = 727 child participants. Only seven of the very/high-quality studies were prospective and involved children. Methylation was the most studied method of epigenetic modification. There is some evidence supporting epigenetic modification of certain markers in participants exposed to ACEs measured in adulthood. Research is lacking on non-coding aspects of the epigenome and on coding aspects other than DNA methylation. There is some evidence of a more powerful effect on telomere length if physical neglect was involved. Much further work is required to model biological and psychological effects of epigenetic changes during childhood using prospective study designs. The effect of ACEs on the cellular ageing process during childhood is inadequately investigated and relies solely on measure of telomere length. Future research suggestions are proposed.


2020 ◽  
Vol 177 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Kyle C. Esteves ◽  
Christopher W. Jones ◽  
Mark Wade ◽  
Keegan Callerame ◽  
Alicia K. Smith ◽  
...  

2018 ◽  
Vol 132 ◽  
pp. 244-251 ◽  
Author(s):  
Christine L. Lackner ◽  
Diane L. Santesso ◽  
Jane Dywan ◽  
Deborah D. O’Leary ◽  
Terrance J. Wade ◽  
...  

2017 ◽  
Vol 30 (4) ◽  
pp. 1211-1223 ◽  
Author(s):  
Or Dagan ◽  
Arun Asok ◽  
Howard Steele ◽  
Miriam Steele ◽  
Kristin Bernard

AbstractExposure to childhood adversity has been linked to accelerated telomere shortening, a marker of cellular aging and an indicator of physical health risk. In the current study, we examined whether adult attachment representation moderated the association between childhood adversity and telomere length. Participants included 78 young adults (M age = 20.46, SD = 1.57), who reported on their exposure to adverse childhood experiences (ACE) and were administered the Adult Attachment Interview, which was coded for attachment state of mind. Relative telomere length was assayed from buccal cells. Multiple regression analyses revealed a significant interaction between attachment state of mind and ACE in predicting telomere length. Whereas the association between number of ACE and telomere length was nonsignificant for secure–autonomous, r (50) = –.15, p = .31, and insecure–preoccupied young adults, r (9) = –.15, p = .71, there was a strong negative association between number of ACE and telomere length for insecure–dismissing young adults, r (19) = –.59, p = .007. This study is novel in demonstrating that attachment may affect biological resilience following childhood adversity, contributing to the growing literature about the role of the quality of early caregiving experiences and their representations in shaping biological processes and physical health.


Author(s):  
Chien-Chung Huang ◽  
Yuanfa Tan ◽  
Shannon P. Cheung ◽  
Hongwei Hu

Literature on the antecedents of psychological well-being (PWB) has found that adverse childhood experiences (ACEs) and mindfulness are associated with PWB; less is known, however, about the role of mindfulness, a type of emotional and self-regulation, in the pathway between ACEs and PWB. This study used data from 1871 college students across China to examine the relation between ACEs and PWB, and whether the relation was mediated by mindfulness. The findings from structural equation modelling indicate a statistically significant negative association between ACEs and PWB, while mindfulness was strongly and positively associated with PWB. The effect of ACEs on PWB was reduced once mindfulness was controlled for in the analysis. This provides evidence that mindfulness was able to partially mediate the effects of negative life experiences on psychological well-being. This calls for mindfulness interventions targeted toward students with a history of ACEs to buffer the effects of ACEs on PWB.


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