scholarly journals Obstructive sleep apnoea and polycystic ovary syndrome: A comprehensive review of clinical interactions and underlying pathophysiology

2017 ◽  
Vol 87 (4) ◽  
pp. 313-319 ◽  
Author(s):  
Hassan Kahal ◽  
Ioannis Kyrou ◽  
Abd A. Tahrani ◽  
Harpal S. Randeva
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Obstructive Sleep Apnoea ◽  
Polycystic Ovary ◽  
Sleep Apnoea ◽  
Ovary Syndrome ◽  
Comprehensive Review ◽  
Obstructive Sleep ◽  
Clinical Interactions ◽  
Underlying Pathophysiology

scholarly journals Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study

2019 ◽  
Vol 180 (4) ◽  
pp. 265-272 ◽  
Author(s):  
Balachandran Kumarendran ◽  
Dana Sumilo ◽  
Michael W O’Reilly ◽  
Konstantinos A Toulis ◽  
Krishna M Gokhale ◽  
...  
Keyword(s):  
Cohort Study ◽  
Polycystic Ovary Syndrome ◽  
Obstructive Sleep Apnoea ◽  
Polycystic Ovary ◽  
Population Based ◽  
Sleep Apnoea ◽  
Ovary Syndrome ◽  
Obstructive Sleep ◽  
Increased Risk

Objective Obesity is very common in patients with obstructive sleep apnoea (OSA) and polycystic ovary syndrome (PCOS). Longitudinal studies assessing OSA risk in PCOS and examining the role of obesity are lacking. Our objective was to assess the risk of OSA in women with vs without PCOS and to examine the role of obesity in the observed findings. Design Population-based retrospective cohort study utilizing The Health Improvement Network (THIN), UK. Methods 76 978 women with PCOS and 143 077 age-, BMI- and location-matched women without PCOS between January 2000 and May 2017 were identified. Hazard ratio (HR) for OSA among women with and without PCOS were calculated after controlling for confounding variables using multivariate Cox models. Results Median patient age was 30 (IQR: 25–35) years; median follow-up was 3.5 (IQR: 1.4–7.1) years. We found 298 OSA cases in PCOS women vs 222 in controls, with incidence rates for OSA of 8.1 and 3.3 per 10 000 person years, respectively. Women with PCOS were at increased risk of developing OSA (adjusted HR = 2.26, 95% CI: 1.89–2.69, P < 0.001), with similar HRs for normal weight, overweight and obese PCOS women. Conclusions Women with PCOS are at increased risk of developing OSA compared to control women irrespective of obesity. Considering the significant metabolic morbidity associated with OSA, clinicians should have a low threshold to test for OSA in women with PCOS. Whether OSA treatment has an impact on PCOS symptoms and outcomes needs to be examined.

scholarly journals The prevalence of obstructive sleep apnoea in women with polycystic ovary syndrome: a systematic review and meta-analysis

2019 ◽  
Vol 24 (1) ◽  
pp. 339-350 ◽  
Author(s):  
Hassan Kahal ◽  
Ioannis Kyrou ◽  
Olalekan A. Uthman ◽  
Anna Brown ◽  
Samantha Johnson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Polycystic Ovary Syndrome ◽  
Obstructive Sleep Apnoea ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Sleep Apnoea ◽  
Ovary Syndrome ◽  
Obstructive Sleep

scholarly journals A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS)

2019 ◽  
Vol 27 (2) ◽  
pp. 863-877 ◽  
Author(s):  
Arezoo Moini Jazani ◽  
Hamidreza Nasimi Doost Azgomi ◽  
Alireza Nasimi Doost Azgomi ◽  
Ramin Nasimi Doost Azgomi
Keyword(s):  
Herbal Medicine ◽  
Polycystic Ovary Syndrome ◽  
Clinical Studies ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Comprehensive Review
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