This chapter covers the fundamentals of the diagnosis, prevention, and treatment of periodontal disease, alongside the most recent classification system. The epidemiology of periodontal disease is discussed before the key aspects of clinical examination are explained. The relevance and implications of plaque and calculus are detailed including their composition and pathological effects. The chapter includes the clinical features of periodontal diseases, including aggressive periodontitis, necrotizing periodontal diseases, and periodontal abscesses, as well as periodontitis associated with endodontic lesions. The principles of periodontal surgery are described, covering local anaesthetic techniques, flap design, and suturing techniques, as well as regenerative techniques and mucogingival surgery.