Occupational contact dermatitis caused by methylchloroisothiazolinone/methylisothiazolinone through exposure to filler dust containing this preservative and with a positive patch test reaction to the dust

Abstract Background Occupational skin diseases are common suggesting that there are still gaps in workplace prevention. Patch test surveillance systems provide an opportunity to collect work related information in addition to clinical information and patch test results. Objectives To examine 5 years of data related to workplace prevention by industry sector in a patch test surveillance database for workers with a diagnosis of occupational contact dermatitis. Methods The study was approved by the Research Ethics Board of St Michael’s Hospital. Information including demographics, clinical history, healthcare utilization, and workplace characteristics and prevention practices in addition to patch test results was collected from consenting patients. Results Workers in the healthcare and manufacturing sectors were more likely to report workplace training including skin protection training, whereas those in services and construction were less likely to report training. Conclusions Collecting basic workplace information with patch test surveillance databases can inform the occupational health and safety system about prevention practices in the workplace and identify areas for focussed intervention.

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Occupational contact dermatitis in Triveneto: Analysis of patch test data of the North Eastern Italian Database from 1996 to 2016

Contact Dermatitis ◽

10.1111/cod.13512 ◽

2020 ◽

Vol 82 (6) ◽

pp. 370-379

Author(s):

Monica Santarossa ◽

Marcella Mauro ◽

Anna Belloni Fortina ◽

Maria T. Corradin ◽

Francesca Larese Filon

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Test Data ◽

Occupational Contact Dermatitis ◽

The North ◽

North Eastern ◽

Occupational Contact

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Using Patch Testing to Improve Therapeutic Outcome in the Treatment of Hand Eczema in Vietnamese Patients

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.051 ◽

2019 ◽

Vol 7 (2) ◽

pp. 204-207 ◽

Cited By ~ 1

Author(s):

Phuong Pham Thi Minh ◽

Trang Thi Minh ◽

Doanh Le Huu ◽

Thuong Nguyen Van ◽

Sau Nguyen Huu ◽

...

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Clinical Features ◽

Potassium Dichromate ◽

Nickel Sulfate ◽

Hand Eczema ◽

Test Reaction ◽

Positive Patch Test ◽

Causative Agents ◽

Allergic Contact

BACKGROUND: Hand eczema is a common chronic and relapsing skin disease with various clinical features. Hand eczema aetiology can be allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), atopic dermatitis (AD) and unknown or combination causes. If the causative agents are not detected treatment of hand eczema will be a failure. A patch test can be useful to detect causative agents in suspected allergic contact hand eczema. Then patients will avoid contacting them. This results in the improvement of hand eczema. In Vietnam, patch test has not been used before, so we conduct this study. AIM: To identify causative allergens by using patch test with 28 standard allergens in consecutive patients. METHODS: A group of 300 HE patients from the National Hospital of Dermatology and Venereology (NHDV) in Vietnam were enrolled in this study. They were divided into 4 groups-ACD, ICD, AD and unknown aetiology. The patient was patch tested with 28 standard allergens to identify the causative agents. RESULTS: Among the 300 HE enrolled patients, ACD accounted for 72.7%, AD and ICD had the same rate of 12.7%. 39.3% of the patients had a positive patch test. Reaction to nickel sulfate was the most common (10.3%), followed by potassium dichromate (9.7%), cobalt (4%) and fragrance mix (3.1%). About one-third of the cases had relevant clinical reactions correlated with the contact agents and clinical history. Males reacted to cement, thiuram mix and formaldehyde more than females, while females reacted to a nickel more than males. CONCLUSIONS: Hand eczema has variable clinical features and diverse aetiology. ACD is an important cause of hand eczema that can be managed with a patch test to detect causative allergens. Nearly 40% of HE cases had positive patch test. Relevant patch test reactions were seen in one-third of the patients. We propose using patch test detect causative agents in suspected allergic contact hand eczema. Then patients will avoid contacting them. This results in the improvement of hand eczema.

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Patch test results of the European baseline series among patients with occupational contact dermatitis across Europe - analyses of the European Surveillance System on Contact Allergy network, 2002-2010

Contact Dermatitis ◽

10.1111/cod.12333 ◽

2015 ◽

Vol 72 (3) ◽

pp. 154-163 ◽

Cited By ~ 101

Author(s):

Maria Pesonen ◽

Riitta Jolanki ◽

Francesca Larese Filon ◽

Mark Wilkinson ◽

Beata Kręcisz ◽

...

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Surveillance System ◽

Contact Allergy ◽

Test Results ◽

Occupational Contact Dermatitis ◽

Occupational Contact

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Results of patch tests (using Indian standard battery of allergens) in cement workers with clinically diagnosed allergic contact dermatitis to cement: A cross-sectional study

Journal of Skin and Sexually Transmitted Diseases ◽

10.25259/jsstd_60_2021 ◽

2021 ◽

Vol 0 ◽

pp. 1-5

Author(s):

Thacharamban Mansoorali ◽

Abdulsalam Sarin

Keyword(s):

Contact Dermatitis ◽

Allergic Contact Dermatitis ◽

Patch Test ◽

Positive Reaction ◽

Patch Testing ◽

Tertiary Referral ◽

Test Reaction ◽

Tertiary Referral Center ◽

Positive Patch Test ◽

Allergic Contact

Objectives: The objective of the study was to identify the allergens showing positive patch test reaction (using Indian standard battery of allergens) in cement workers with clinically diagnosed allergic contact dermatitis (CD) to cement attending a tertiary referral center. Materials and Methods: We included cement workers with clinically diagnosed allergic CD to cement who attended the dermatology outpatient clinic of our tertiary referral center from January 2013 to December 2013. We did patch testing in all the cases ( after subsidence of active dermatitis) with Indian standard battery of patch test allergens and documented the allergens that showed a positive reaction. Results: Forty-seven (94%) of the 50 study participants showed a positive reaction to one or more of the allergens. The most common allergen that showed a positive reaction was potassium dichromate (43/50, 86%). Twenty-five patients (50%) showed positive reactions to more than 1 allergen. Four patients (8%) showed positive reactions only to allergens that were not seen in cement. Limitations: Small sample size and lack of information on clinical response of dermatitis to avoidance of identified allergen were the major limitations. Conclusion: Twenty-five (50%) patients showing positive reactions to more than 1 allergen tested and 4 (8%) showing positive patch test reaction to none of the allergens in cement (but to other allergens) highlight the role of patch testing in identifying the probable allergens in patients with clinically diagnosed allergic CD to cement.

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Occupational contact dermatitis in painters - an analysis of patch test data from the Danish Contact Dermatitis Group

Contact Dermatitis ◽

10.1111/j.1600-0536.2012.02074.x ◽

2012 ◽

Vol 67 (5) ◽

pp. 293-297 ◽

Cited By ~ 52

Author(s):

Anja P. Mose ◽

Michael D. Lundov ◽

Claus Zachariae ◽

Torkil Menné ◽

Niels K. Veien ◽

...

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Test Data ◽

Occupational Contact Dermatitis ◽

Occupational Contact

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Role of footwear allergens in juvenile plantar dermatosis

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20171569 ◽

2017 ◽

Vol 3 (2) ◽

pp. 223

Author(s):

Shyni Perumbil ◽

Kunnummal Muhammed ◽

Sarita Sasidharan Pillai

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Potassium Dichromate ◽

Past History ◽

Test Reaction ◽

Positive Patch Test ◽

International Contact ◽

History Of ◽

Age And Sex

Background: Juvenile plantar dermatosis (JPD) is characterized by shiny dry fissured dermatitis of the plantar surface of the foot, affecting children aged 3-14years. The most accepted theory is that JPD is a frictional contact dermatitis of the forefoot in which atopics are more prone to develop. Allergic contact dermatitis remains a close differential diagnosis; it can aggravate the predisposing JPD. In this background we carried out a study among children aged fourteen years and below with clinically diagnosed JPD to know the age and sex profile, aggravating factors and clinical features in this part of the country.Methods: All children aged 14 years and below with JPD attending our outpatient department from November 2006 to November 2007 were included in this study. Using a preset proforma, data regarding age and sex, information on any relation to footwear, past history of allergic disorders in person or family members was collected. All the 40 patients were patch tested using the footwear allergen series in petrolatum base. Patch test unit was removed after 48hours and the results were interpreted using criteria laid down by International Contact Dermatitis Group (ICDRG). The data was analyzed and made an attempt to understand the role of footwear allergy in JPD.Results: 22 girls and 18 boys attended our OPD with JPD between the age group of 4-14 years. 52.5% were using footwear made of plastic; 25%used leather; 12.5% rubber footwear. Patients presented with erythema and glazed appearance of foot along with fissuring. The areas of involvement were distal soles and toes in 70%, distal sole alone in 7.5% and distal sole and dorsum of toes in 22.5% of patients. Personal history of atopy was documented in 15% of patients and family history of atopy was present in 20% of cases. 20% of patients complained of exacerbation with footwear. Of the 40 patients who underwent patch testing, 10% only showed positive patch test reaction mainly to potassium dichromate (5%). Conclusions: JPD is not an uncommon disease and it predominantly affects school going children. Seasonal variation was associated with aggravation of disease. Specific footwear was identified to cause flare ups in a significant percentage of study population (20%) and this was proven by patch test results in half of them. Though nearly one fifth of the affected had an atopic diathesis in person or family, the present data suggests that JPD is not exclusive to atopics. A large sized study is required to evaluate the role of footwear in JPD.

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