Safety and Pharmacokinetics of the Oral TYK2 Inhibitor PF‐06826647: A Phase I, Randomized, Double‐Blind, Placebo‐Controlled, Dose‐Escalation Study

Clinical and Translational Science ◽

10.1111/cts.12929 ◽

2020 ◽

Cited By ~ 1

Author(s):

Ravi Shankar P. Singh ◽

Vivek Pradhan ◽

Erika S. Roberts ◽

Matthew Scaramozza ◽

Elizabeth Kieras ◽

...

Keyword(s):

Phase I ◽

Dose Escalation ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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A phase I, randomized, double‐blind, placebo‐controlled, single‐ and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX‐128, a highly selective Na v 1.8 inhibitor, in healthy adults

Clinical and Translational Science ◽

10.1111/cts.13215 ◽

2021 ◽

Author(s):

Hemme J. Hijma ◽

Emilie M. J. Brummelen ◽

Pieter S. Siebenga ◽

Geert Jan Groeneveld

Keyword(s):

Phase I ◽

Dose Escalation ◽

Multiple Dose ◽

Healthy Adults ◽

Pharmacokinetics And Pharmacodynamics ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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Phase I, randomized, double-blind, placebo-controlled, single-dose escalation study of the recombinant factor VIIa variant BAY 86-6150 in hemophilia

Journal of Thrombosis and Haemostasis ◽

10.1111/j.1538-7836.2012.04667.x ◽

2012 ◽

Vol 10 (5) ◽

pp. 773-780 ◽

Cited By ~ 31

Author(s):

J. N. MAHLANGU ◽

M. J. COETZEE ◽

M. LAFFAN ◽

J. WINDYGA ◽

T. T. YEE ◽

...

Keyword(s):

Single Dose ◽

Phase I ◽

Dose Escalation ◽

Recombinant Factor Viia ◽

Factor Viia ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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493 Safety Profile and Signal of Efficacy of a Non-Fcr-Binding, Fully Human Anti-Cd3 Monoclonal Antibody in Patients with Moderate to Severe Crohn's Disease- Results of a Phase I/Iia, Double Blind, Placebo-Controlled, Randomized, Dose Escalation Study

Gastroenterology ◽

10.1016/s0016-5085(08)60317-0 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-67 ◽

Cited By ~ 2

Author(s):

Christien J. van der Woude ◽

Pieter C. Stokkers ◽

Ad A. van Bodegraven ◽

Gert A. Van Assche ◽

Zbigniew Hebzda ◽

...

Keyword(s):

Monoclonal Antibody ◽

Crohn’S Disease ◽

Crohn's Disease ◽

Phase I ◽

Dose Escalation ◽

Safety Profile ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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Faculty Opinions recommendation of A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13409136.14780164 ◽

2011 ◽

Author(s):

John Laffey ◽

Mairead Hayes

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Dose Escalation ◽

Human Mesenchymal Stem Cells ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Adult Human

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Pharmacokinetics, Safety, and Tolerability of Intravenous Felbinac Trometamol in Healthy Chinese Volunteers: A First-in-Human Single- and Multiple-Dose Escalation Phase I Study with a Randomized, Double-Blind, Placebo-Controlled Design

CNS Drugs ◽

10.1007/s40263-020-00739-z ◽

2020 ◽

Vol 34 (8) ◽

pp. 867-877

Author(s):

Min Wu ◽

Cuiyun Li ◽

Hong Zhang ◽

Jixuan Sun ◽

Xiaoxue Zhu ◽

...

Keyword(s):

Phase I ◽

Dose Escalation ◽

Phase I Study ◽

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Healthy Chinese

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A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

Yearbook of Cardiology ◽

10.1016/s0145-4145(10)79814-2 ◽

2010 ◽

Vol 2010 ◽

pp. 389-391 ◽

Cited By ~ 3

Author(s):

B.J. Gersh

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Dose Escalation ◽

Human Mesenchymal Stem Cells ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Adult Human

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First-In-Human, Double-Blind, Placebo-Controlled, Randomized, Dose-Escalation Study of BG00010, a Glial Cell Line-Derived Neurotrophic Factor Family Member, in Subjects with Unilateral Sciatica

PLoS ONE ◽

10.1371/journal.pone.0125034 ◽

2015 ◽

Vol 10 (5) ◽

pp. e0125034 ◽

Cited By ~ 16

Author(s):

Paul E. Rolan ◽

Gilmore O’Neill ◽

Eve Versage ◽

Jitesh Rana ◽

Yongqiang Tang ◽

...

Keyword(s):

Family Member ◽

Cell Line ◽

Glial Cell ◽

Dose Escalation ◽

Neurotrophic Factor ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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A phase I, single-dose, double-blind, randomised, dose escalation study to assess the safety, tolerability and pharmacokinetics of NNZ-2566 when administered as a 10-minute infusion

http://isrctn.org/> ◽

10.1186/isrctn67656669 ◽

2013 ◽

Author(s):

Minh Pham

Keyword(s):

Single Dose ◽

Phase I ◽

Dose Escalation ◽

Dose Escalation Study ◽

Double Blind

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Safety and Immunogenicity of a Plant-Produced Recombinant Hemagglutinin-Based Influenza Vaccine (HAI-05) Derived from A/Indonesia/05/2005 (H5N1) Influenza Virus: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study in Healthy Adults

Viruses ◽

10.3390/v4113227 ◽

2012 ◽

Vol 4 (11) ◽

pp. 3227-3244 ◽

Cited By ~ 48

Author(s):

Jessica Chichester ◽

R. Jones ◽

Brian Green ◽

Mark Stow ◽

Fudu Miao ◽

...

Keyword(s):

Influenza Virus ◽

Influenza Vaccine ◽

Dose Escalation ◽

Phase 1 ◽

H5n1 Influenza Virus ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

H5n1 Influenza ◽

Recombinant Hemagglutinin

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Erratum: A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

Molecular Psychiatry ◽

10.1038/mp.2016.140 ◽

2016 ◽

Vol 21 (10) ◽

pp. 1483-1484 ◽

Cited By ~ 5

Author(s):

M Fava ◽

K Johe ◽

L Ereshefsky ◽

L G Gertsik ◽

B A English ◽

...

Keyword(s):

Dose Escalation ◽

Multiple Dose ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Depressed Patients ◽

Phase 1B

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