Concurrent cutaneous localization of Langerhans cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma in a patient with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma

2019 ◽  
Vol 47 (2) ◽  
pp. 161-165 ◽  
Author(s):  
Alexandra Papoudou‐Bai ◽  
Amalia Vassou ◽  
Leonidas Marinos ◽  
Konstantina Papathanasiou ◽  
Eleni Kapsali ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Langerhans Cell ◽  
Lymphocytic Leukemia ◽  
Small Lymphocytic Lymphoma ◽  
Cell Sarcoma ◽  
Langerhans Cell Sarcoma ◽  
Cutaneous Localization ◽  
History Of

Bone marrow coexistence of chronic lymphocytic leukemia and Langerhans cell sarcoma

2020 ◽  
Author(s):  
Magda Zanelli ◽  
Stefano Ricci ◽  
Maurizio Zizzo ◽  
Francesca Sanguedolce ◽  
Giovanni Martino ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Chronic Lymphocytic Leukemia ◽  
Langerhans Cell ◽  
Lymphocytic Leukemia ◽  
Cell Sarcoma ◽  
Langerhans Cell Sarcoma

scholarly journals Langerhans cell sarcoma arising from chronic lymphocytic lymphoma/small lymphocytic leukemia: lineage analysis and braf v600e mutation study

2013 ◽  
Vol 5 (6) ◽  
pp. 386 ◽  
Author(s):  
Donghong Cai ◽  
Weiwei Chen ◽  
Ronald Jaffe ◽  
Linsheng Zhang ◽  
Charlie Hill ◽  
...  
Keyword(s):  
Braf V600e Mutation ◽  
Langerhans Cell ◽  
Lymphocytic Leukemia ◽  
Braf V600e ◽  
Cell Sarcoma ◽  
Langerhans Cell Sarcoma ◽  
Lineage Analysis

Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma to Interdigitating Dendritic Cell Sarcoma

2009 ◽  
Vol 132 (6) ◽  
pp. 928-939 ◽  
Author(s):  
Cory R. Fraser ◽  
Wei Wang ◽  
Mario Gomez ◽  
Taotao Zhang ◽  
Susan Mathew ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Small Lymphocytic Lymphoma ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma ◽  
Interdigitating Dendritic Cell Sarcoma

scholarly journals Other Malignancies in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

2009 ◽  
Vol 27 (6) ◽  
pp. 904-910 ◽  
Author(s):  
Apostolia-Maria Tsimberidou ◽  
Sijin Wen ◽  
Peter McLaughlin ◽  
Susan O'Brien ◽  
William G. Wierda ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Survival Rates ◽  
Lymphocytic Leukemia ◽  
Cancer Center ◽  
Second Cancer ◽  
Small Lymphocytic Lymphoma ◽  
University Of Texas ◽  
History Of ◽  
Cox Analysis ◽  
The University

Purpose Other malignancies have been reported to occur with increased frequency in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). The aim of this study was to determine the frequency, outcomes, and factors associated with other cancers in patients with CLL/SLL. Patients and Methods We reviewed the records of consecutive patients with previously untreated CLL/SLL seen at The University of Texas M. D. Anderson Cancer Center from 1985 to 2005. The number of second cancers observed was compared with the number expected from the Surveillance, Epidemiology, and End Results database. Results Among 2,028 patients, 324 (16%) had a history of other cancers and 227 (11.2%) developed other malignancies during the follow-up period. Overall, 625 cancers were observed in 551 patients, including skin (30%), prostate (13%), breast (9%), melanoma (8%), lymphoma (8%), gastrointestinal (9%), lung (6%), and other cancers (17%). The risk of a second cancer was 2.2 times higher than the expected risk. The response rates in patients with and without a history of other cancers were 86% and 92%, respectively (P = .04), and the 5-year survival rates were 70% and 82%, respectively (P < .001). In Cox analysis, independent factors predicting development of new cancers were older age, male sex, and elevated levels of β2-microglobulin, lactate dehydrogenase, and creatinine. In patients who were treated for CLL/SLL, the treatment regimen did not affect the risk of subsequent cancer (P = .49). Conclusion Patients with CLL/SLL have more than twice the risk of developing a second cancer and an increased frequency of certain cancer types. Awareness of risk factors could permit early detection.

scholarly journals Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Michelle Bernshteyn ◽  
Alexandria Smith-Hannah ◽  
Amit S. Dhamoon
Keyword(s):  
Myocardial Infarction ◽  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Chronic Lymphocytic Leukemia ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymphocytic Leukemia ◽  
Small Lymphocytic Lymphoma ◽  
Metastatic Squamous Cell Carcinoma ◽  
History Of

A 66-year-old woman presented to the hospital with a one-month history of shortness of breath, fatigue, and postmenopausal vaginal bleeding and a one-week history of chest pain. This case report discusses the rare synchronous occurrence of two different malignancies in the setting of non-ST segment elevation myocardial infarction and the relation between these unfortunate events. Besides the case presented in this report, there have been only 13 reported cases of synchronous chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) associated with metastatic squamous cell carcinoma. While it is well known that malignancy causes a hypercoagulable state, there are other mechanisms which may have contributed to the patient’s myocardial ischemia including external vascular compression, tumor lysis syndrome, and anemia. This case report discusses the rarity of synchronous malignancies but the importance of understanding and consideration of cardiac events in this population.

scholarly journals Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a study of seven cases

2011 ◽  
Vol 24 (11) ◽  
pp. 1421-1432 ◽  
Author(s):  
Haipeng Shao ◽  
Liqiang Xi ◽  
Mark Raffeld ◽  
Andrew L Feldman ◽  
Rhett P Ketterling ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Small Lymphocytic Lymphoma ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma

scholarly journals Composite Thymoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Involving the Anterior Mediastinum

2003 ◽  
Vol 127 (2) ◽  
pp. e76-e79
Author(s):  
Joseph D. Khoury ◽  
Hesham M. Amin ◽  
Jeffrey L. Jorgensen ◽  
Mary L. Ostrowski ◽  
M. G. Kim Bloom ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Chronic Lymphocytic Leukemia ◽  
Peripheral Blood ◽  
Bone Marrow Aspiration ◽  
Anterior Mediastinum ◽  
Lymphocytic Leukemia ◽  
Anterior Mediastinal Mass ◽  
Differential Count ◽  
Small Lymphocytic Lymphoma ◽  
History Of

Abstract Simultaneous involvement of the anterior mediastinum by thymoma and B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), to our knowledge, has not been previously reported. We describe a composite tumor composed of thymoma and CLL/SLL incidentally discovered in a 62-year-old man who had no history of malignant diseases or immunologic disorders. The preoperative peripheral blood specimen showed a normal complete blood cell count and differential count. The diagnosis was established by histologic examination and immunophenotypic studies of the surgically excised anterior mediastinal mass. Postoperatively, bone marrow aspiration and biopsy specimens showed morphologic evidence of CLL/SLL, and the presence of neoplastic cells in peripheral blood and bone marrow was confirmed by flow cytometry immunophenotypic analysis.

scholarly journals An Unusual Presentation of CLL/SLL on Mammography: Case Report

2020 ◽  
Author(s):  
Anas Mohamed ◽  
Ahmed Younes ◽  
John Stephen Stalls ◽  
Aisha Kousar ◽  
Tian Li
Keyword(s):  
Case Report ◽  
Chronic Lymphocytic Leukemia ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Contralateral Breast ◽  
Lymphocytic Leukemia ◽  
Small Lymphocytic Lymphoma ◽  
History Of

Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) of the breast is rare. We report a 59-year-old female with remote history of ductal carcinoma in situ treated with radiation and tamoxifen, who was recently diagnosed with CLL/SLL of contralateral breast after a localized suspicious cluster of masses was detected on routine mammography.

scholarly journals Langerhans Cell Sarcoma Arising from Small Lymphocytic Lymphoma: Lineage Analysis and BRAF V600E Mutation study

2013 ◽  
Vol 140 (suppl 1) ◽  
pp. A214-A214
Author(s):  
Weiwei Chen ◽  
Ronald Jaffe ◽  
Annemarie Block ◽  
Sheila Sait ◽  
Buer Song ◽  
...  
Keyword(s):  
Braf V600e Mutation ◽  
Langerhans Cell ◽  
Braf V600e ◽  
Small Lymphocytic Lymphoma ◽  
Cell Sarcoma ◽  
Langerhans Cell Sarcoma ◽  
Lineage Analysis
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