scholarly journals Phäohyphomykose durch Cladosporium cladosporioides bei einem immunsupprimierten Jungen mit Ewing‐Sarkom

2021 ◽  
Vol 19 (8) ◽  
pp. 1204-1206
Author(s):  
Dorothea Kratzsch ◽  
Pietro Nenoff ◽  
Silke Uhrlaß ◽  
Susanne Wendt ◽  
Jan‐Christoph Simon ◽  
...  
2014 ◽  
Vol 34 (02) ◽  
pp. 90-98
Author(s):  
F. Hopf ◽  
S. Müller ◽  
B. Kölbel ◽  
V. Krenn

ZusammenfassungIn dieser Übersichtsarbeit wird die histopathologische, immunhistochemische und molekularpathologische Differenzialdiagnostik von neoplastischen und nicht neoplastischen Gelenkerkrankungen dargestellt. Methodisch basiert diese Diagnostik auf konventionellen enzymhistochemischen und immunhistochemischen Färbungen von Formalin-fixierten und Paraffin-eingebetteten Materialien, wie sie in der Routinediagnostik bearbeitet werden und auch für molekulare Diagnoseverfahren einsetzbar sind. Gemäß des Gelenkpathologie-Algorithmus erfolgt die Aufgliederung in neoplastische und entzündliche Erkrankungen. Die wichtigsten neoplastischen Gelenkerkrankungen mit Synovialisbezug umfassen folgende benigne und maligne Neoplasien: Den tenosynovialen Riesenzelltumor (sogenannter PVNS), das intrasynoviale Lipom, das intrasynoviale oder periartikuläre Hämangiom, die synoviale Chondromatose, das Sehnenscheidenfibrom, den allerdings zumeist nicht artikulär lokalisierten solitären fibrösen Tumor (SFT). Die wichtigsten malignen Erkrankungen beinhalten das allerdings nicht notwendigerweise artikulär lokalisierte Synovialsarkom und das skelettale bzw. extraskelettale Ewing-Sarkom. Die histopathologische Differenzialdiagnostik umfasst zusätzlich entzündliche Erkrankungen: Das Spektrum granulomatöser Reaktionen, der Kristallarthropathien, der spezifischen und nicht spezifischen Infektionen sowie der chronischen Synovialitiden, die anhand des Synovialitis-Scores klassifiziert werden.


Author(s):  
Gabriele Calaminus ◽  
Sebastian Weinspach
Keyword(s):  

2021 ◽  
Vol 78 (2) ◽  
pp. 765-774
Author(s):  
Minmin Jing ◽  
Bingyu Huang ◽  
Wen Li ◽  
Jiaoke Zeng ◽  
Yuanzhi Shao

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaoping Ma ◽  
Jing Hu ◽  
Yan Yu ◽  
Chengdong Wang ◽  
Yu Gu ◽  
...  

AbstractCladosporium cladosporioides causes asthma and superficial and deep infections, mostly in immunodeficient individuals and animals. This study aimed to investigate whether C. cladosporioides spores can enter the lungs through pulmonary circulation and influence pulmonary immune response. We intravenously injected mice with C. cladosporioides spore suspension and conducted several assays on the lungs. Pulmonary hemorrhage symptoms and congestion were most severe on days 1, 2, and 3 post-inoculation (PI). Extensive inflammatory cell infiltration occurred throughout the period of infection. More spores and hyphae colonizing the lungs were detected on days 1, 2, and 3 PI, and fewer spores and hyphae were observed within 21 d of infection. Numerous macrophages, dendritic cells, and neutrophils were observed on day 5 PI, along with upregulation of CD54, an intercellular adhesion molecule. Th1 and Th2 cells increased after infection; specifically, Th2 cells increased considerably on day 5 PI. These results suggest that days 2 and 5 PI represent the inflammatory peak in the lungs and that the Th2 and Th1 signaling pathways are potentially involved in pulmonary immune responses. In conclusion, the further adaptive immune responses played important roles in establishing effective pulmonary immunity against C. cladosporioides systemic infections based on innate immune responses.


2013 ◽  
Vol 8 (2) ◽  
pp. 92-95
Author(s):  
Lars-Johannes Lehmann ◽  
Ulrike Attenberger ◽  
Mohamed Moursy ◽  
Frederik Bludau
Keyword(s):  

2010 ◽  
Vol 16 (5) ◽  
pp. 426-437 ◽  
Author(s):  
R. Rudolph ◽  
E. Weiss ◽  
M. Biel
Keyword(s):  

Author(s):  
D. W. Minter

Abstract Descriptions are given of Trimmatostroma scutellare, which are found on dead decaying branches, twigs and cones of conifers, including information on its geographical distribution (USA (California), Russia, Austria, Bulgaria, Czech Republic, UK, Iceland, Norther Ireland, Poland, Sweden, Switzerland and Ukraine), hosts (Abies sp., Cedrus libani, Juniperus communis, Larix decidua, L. europaea, L. kaempferi, L. komarovii, L. sibirica, Larix sp., Pinus contorta, P. maritima var. nigra, P. mugo, P. nigra, P. radiata, P. sibirica, P. sylvestris and Pinus sp.), other associated organisms (Cladosporium cladosporioides and Sclerophoma pithiophila [Sydowia polyspora]), diagnostic features, biology and conservation status.


2018 ◽  
Vol 42 (8) ◽  
pp. 408-411 ◽  
Author(s):  
Kudret Yildirim ◽  
Ali Kuru ◽  
Raşit Fikret Yılmaz

Incubation of testosterone, androstenedione and progesterone with Cladosporium cladosporioides MRC 70282 for 5 days is reported. Testosterone was hydroxylated at C-16β and then oxidised at C-16. This was accompanied by a minor independent oxidation at C-17 and epimerisation at C-17. Androstenedione was reduced at C-17 and hydroxylated at C-16β, and this was then oxidised to a ketone at C-16. This was accompanied by a minor epimerisation at C-17. Progesterone was hydroxylated at C-21, and this was accompanied by a minor independent 5α-reduction.


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