scholarly journals Considerations for stakeholder engagement and COVID ‐19 related clinical trials’ conduct in sub‐Saharan Africa

Author(s):  
Morenike Oluwatoyin Folayan ◽  
Brandon Brown ◽  
Bridget Haire ◽  
Chinedum Peace Babalola ◽  
Nicaise Ndembi
2021 ◽  
Vol 13 (4) ◽  
pp. 2128
Author(s):  
Amollo Ambole ◽  
Kweku Koranteng ◽  
Peris Njoroge ◽  
Douglas Logedi Luhangala

Energy communities have received considerable attention in the Global North, especially in Europe, due to their potential for achieving sustainable energy transitions. In Sub-Saharan Africa (SSA), energy communities have received less attention partly due to the nascent energy systems in many emerging SSA states. In this paper, we argue that these nascent energy systems offer an opportunity to co-create energy communities that can tackle the energy access challenges faced by most SSA countries. To understand how such energy communities are realised in the sub-region, we undertake a systematic review of research on energy communities in 46 SSA countries. Our findings show that only a few energy projects exhibit the conventional characteristics of energy communities; In most of these projects, local communities are inadequately resourced to institute and manage their own projects. We thus look to stakeholder engagement approaches to propose co-design as a strategy for strengthening energy communities in SSA. We further embed our co-design proposal in energy democracy thinking to argue that energy communities can be a pathway towards equity and energy justice in SSA. We conclude that energy communities can indeed contribute to improving energy access in Africa, but they need an enabling policy environment to foster their growth and sustainability.


Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Neema Toto ◽  
Elaine Douglas ◽  
Markus Gmeiner ◽  
Lynn K. Barrett ◽  
Robert Lindblad ◽  
...  

JAMA ◽  
2004 ◽  
Vol 292 (2) ◽  
pp. 237 ◽  
Author(s):  
David M. Kent ◽  
D. Mkaya Mwamburi ◽  
Michael L. Bennish ◽  
Bruce Kupelnick ◽  
John P. A. Ioannidis

PLoS ONE ◽  
2017 ◽  
Vol 12 (3) ◽  
pp. e0173796 ◽  
Author(s):  
Nerina Vischer ◽  
Constanze Pfeiffer ◽  
Manuela Limacher ◽  
Christian Burri

2013 ◽  
Vol 10 (10) ◽  
pp. 599-604 ◽  
Author(s):  
Trijn Israëls ◽  
Joyce Kambugu ◽  
Francine Kouya ◽  
Nader Kim El-Mallawany ◽  
Peter B. Hesseling ◽  
...  

2021 ◽  
pp. 1358-1363
Author(s):  
Abiola Ibraheem ◽  
Colin Pillai ◽  
Ifeoma Okoye ◽  
J. Joshua Smith ◽  
Diane Reidy-Lagunes ◽  
...  

Cancer is now a formidable health care burden in sub-Saharan Africa (SSA) due to lifestyle westernization and longer life expectancy. The exponential increase in cancer incidence coupled with high mortality rate is not comparable with that seen in westernized countries. To address global cancer disparity, globalization of cancer clinical trials to involve sub-Saharan Africa can serve as a platform where innovative targeted therapies can be made available to patients in the environ. In the 2019 African Organization for Research and Training in Cancer (AORTIC) conference held at Maputo, Mozambique, a group of clinical trialists spanning across multiple continents highlighted the opportunities in Africa for the conduct of cancer clinical trials. The secondary purpose of the meeting was to address the belief that Africa was incapable of conducting interventional cancer trials but showed the in-continent strengths, such as available capacities, trained local clinical trialists with clinical trial experiences, clinical trial consortia, local capabilities, mapping out logistics, ethical consideration, political will, real-time benefits of clinical trials to clinical practice, and future directions for trials.


2019 ◽  
Vol 24 (8) ◽  
pp. 649-660 ◽  
Author(s):  
Jane Frances Ndyetukira ◽  
Richard Kwizera ◽  
Florence Kugonza ◽  
Cynthia Ahimbisibwe ◽  
Carol Namujju ◽  
...  

Background Nurses form a very important part of the health workforce in sub-Saharan Africa. Research nurses are critical to the implementation of clinical trials. The duties and responsibilities of a research nurse are complex and continue to evolve as new practices and guidelines are formulated. Aims In this paper, we have highlighted the major contributions of research nurses in HIV clinical trials in sub-Saharan Africa from the unique perspective of Ugandan nurses. Methods The requirements and challenges of two multi-site, randomised cryptococcal meningitis clinical trials in Uganda were assessed from the perspective of research nurses conducting complex research in resource-limited settings. Results Over the course of 8 years, approximately 1739 participants were screened and 934 people were enrolled into the two trials. The nurses found that patient education and engagement were among the most important predictors of success in minimising loss to follow-up. Conclusions Research nurses played a key role in communicating clinical research goals to patients, obtaining informed consent, minimising loss to follow-up, and ensuring that research practices are translated and implemented into standard of care. However, there remains a need to integrate the same level of care provided in clinical research studies to non-study patients.


PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0218556 ◽  
Author(s):  
Kayla Stankevitz ◽  
Katie Schwartz ◽  
Theresa Hoke ◽  
Yixuan Li ◽  
Michele Lanham ◽  
...  

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