scholarly journals Effects on clinical outcomes of intensifying triple oral antidiabetic drug (OAD) therapy by initiating insulin versus enhancing OAD therapy in patients with type 2 diabetes: A nationwide population-based, propensity-score-matched cohort study

2018 ◽  
Vol 21 (2) ◽  
pp. 312-320 ◽  
Author(s):  
Shihchen Kuo ◽  
Chun-Ting Yang ◽  
Jin-Shang Wu ◽  
Huang-Tz Ou
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Propensity Score ◽  
Clinical Outcomes ◽  
Population Based ◽  
Matched Cohort ◽  
Antidiabetic Drug ◽  
Oral Antidiabetic Drug ◽  
Oral Antidiabetic

scholarly journals Effect of Contemporary Bariatric Surgical Procedures on Type 2 Diabetes Remission. A Population-Based Matched Cohort Study

2016 ◽  
Vol 26 (10) ◽  
pp. 2308-2315 ◽  
Author(s):  
Martin C. Gulliford ◽  
◽  
Helen Pascale Booth ◽  
Marcus Reddy ◽  
Judith Charlton ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Surgical Procedures ◽  
Population Based ◽  
Diabetes Remission ◽  
Matched Cohort ◽  
Matched Cohort Study ◽  
Type 2 Diabetes Remission

scholarly journals Effectiveness and Content Analysis of Interventions to Enhance Oral Antidiabetic Drug Adherence in Adults with Type 2 Diabetes: Systematic Review and Meta-Analysis

2015 ◽  
Vol 18 (4) ◽  
pp. 530-540 ◽  
Author(s):  
Hervé Tchala Vignon Zomahoun ◽  
Marijn de Bruin ◽  
Laurence Guillaumie ◽  
Jocelyne Moisan ◽  
Jean-Pierre Grégoire ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Content Analysis ◽  
Meta Analysis ◽  
Drug Adherence ◽  
Antidiabetic Drug ◽  
Oral Antidiabetic Drug ◽  
Oral Antidiabetic

scholarly journals Real-world Observational Study on Patient Outcomes in Diabetes (RESPOND): study design and baseline characteristics of patients with type 2 diabetes newly initiating oral antidiabetic drug monotherapy in Japan

2020 ◽  
Vol 8 (2) ◽  
pp. e001361
Author(s):  
Daisuke Yabe ◽  
Hiroko Higashiyama ◽  
Takashi Kadowaki ◽  
Hideki Origasa ◽  
Iichiro Shimomura ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Patient Outcomes ◽  
Real World ◽  
Glycated Hemoglobin ◽  
Self Care ◽  
Antidiabetic Drug ◽  
Oral Antidiabetic Drug ◽  
Oral Antidiabetic ◽  
Diet And Exercise

IntroductionTo investigate factors affecting glycemic control, oral antidiabetic drug (OAD) treatment distribution and self-care activities among patients with type 2 diabetes mellitus (T2DM) who newly initiate OAD monotherapy in a real-world setting in Japan.Research design and methodsA Real-world Observational Study on Patient Outcomes in Diabetes (RESPOND) is an ongoing, prospective, observational cohort study with follow-up at 6, 12, 18 and 24 months. Primary objectives include OAD treatment patterns (cross-sectional and longitudinal) among diabetes specialists versus non-specialists; adherence to diabetes self-care activities; quality of life; treatment satisfaction among patients and target attainment rates of parameters, including glycated hemoglobin. Here, we present the study design and baseline data.ResultsOf 1506 patients enrolled (June 2016–May 2017; 174 sites in Japan), 1485 were included in the baseline analysis (617 treated by specialists, 868 by non-specialists). Most patients were prescribed dipeptidyl peptidase-4 inhibitors (DPP-4Is) (specialist vs non-specialist, 54.1% vs 57.1%), then sodium-glucose cotransporter 2 inhibitors (13.9% vs 22.2%), metformin (20.3% vs 12.9%) and other OADs (<5% individually in both groups). Regardless of age, body mass index and glycated hemoglobin, DPP-4Is were the most commonly prescribed OADs by both specialists and non-specialists. About one-fifth and one-third of patients visiting specialists and non-specialists, respectively, received no advice on diet and exercise. The proportion of patients following self-care recommendations for diet and exercise (2/5 items on the Summary of Diabetes Self-Care Activities) was significantly higher among those visiting specialists than non-specialists.ConclusionThe use of newer OAD was common across a broad range of clinical characteristics in patients with T2DM who newly initiated monotherapy in Japan. However, patient-related and physician-related factors could affect the treatment changes during the following course of treatment. In addition, treatment outcome could vary with the observed difference in the level of patient education provided by diabetes specialists versus non-specialists.

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