scholarly journals Hippocampal profiling: Localized magnetic resonance imaging volumetry and T2 relaxometry for hippocampal sclerosis

Epilepsia ◽  
2019 ◽  
Vol 61 (2) ◽  
pp. 297-309 ◽  
Author(s):  
Sjoerd B. Vos ◽  
Gavin P. Winston ◽  
Olivia Goodkin ◽  
Hugh G. Pemberton ◽  
Frederik Barkhof ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hippocampal Sclerosis ◽  
Resonance Imaging ◽  
T2 Relaxometry

scholarly journals Novel approach to magnetic resonance imaging of epileptic dogs — T2 relaxometry of the brain with emphasised hippocampus

2017 ◽  
Vol 65 (2) ◽  
pp. 185-197 ◽  
Author(s):  
Borbála A. Lorincz ◽  
Agustina Anson ◽  
Péter Csébi ◽  
Gábor Bajzik ◽  
Gergely Biró ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hippocampal Sclerosis ◽  
Relaxation Times ◽  
Visual Assessment ◽  
Resonance Imaging ◽  
T2 Relaxation ◽  
T2 Relaxometry ◽  
Individual Analysis ◽  
Skull Formation

Hippocampal sclerosis is the most common imaging finding of intractable human epilepsy, and it may play an important role in canine and feline epileptogenesis and seizure semiology, too. The magnetic resonance imaging (MRI) criteria of hippocampal sclerosis are T2 hyperintensity, shrinkage and loss of internal structure. The detection of these changes is often challenging by subjective visual assessment of qualitative magnetic resonance (MR) images. The recognition is more reliable with quantitative MR methods, such as T2 relaxometry. In the present prospective study including 31 dogs with idiopathic epilepsy and 15 control dogs showing no seizure activity, we compared the T2 relaxation times of different brain areas. Furthermore, we studied correlations between the hippocampal T2 values and age, gender and skull formation. We found higher hippocampal T2 values in the epileptic group than in the control; however, these findings were not statistically significant. No correlations were found with age, gender or skull formation. In the individual analysis six epileptic dogs presented higher hippocampal T2 relaxation times than the cut-off value. Two of these dogs were also evaluated as abnormal in the visual assessment. Individual analysis of hippocampal T2 relaxation times may be a helpful method to understand hippocampal involvement in canine epilepsy.

The spectrum of hippocampal sclerosis: A quantitative magnetic resonance imaging study

1997 ◽  
Vol 41 (1) ◽  
pp. 41-51 ◽  
Author(s):  
W. Van Paesschen ◽  
A. Connelly ◽  
M. D. King ◽  
G. D. Jackson ◽  
J. S. Duncan
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hippocampal Sclerosis ◽  
Imaging Study ◽  
Magnetic Resonance Imaging Study ◽  
Resonance Imaging ◽  
Quantitative Magnetic Resonance Imaging ◽  
Quantitative Magnetic Resonance

Adverse effects of erenumab on cerebral proliferative angiopathy: A case report

Cephalalgia ◽  
2020 ◽  
pp. 033310242095048
Author(s):  
Laura L Lehman ◽  
Rebecca Bruccoleri ◽  
Amy Danehy ◽  
Julie Swanson ◽  
Christine Mrakotsky ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Blood Brain Barrier ◽  
Vascular Malformations ◽  
Hippocampal Sclerosis ◽  
White Matter Injury ◽  
Brain Barrier ◽  
Resonance Imaging ◽  
Blood Brain

Background Cerebral proliferative angiopathy is a vascular malformation associated with compromised blood-brain barrier and with migraine-like headache. Treating blood-brain barrier-compromised patients with erenumab, an anti-calcitonin gene-related peptide receptor monoclonal antibody, may be risky. Case We describe a case of a 22-year-old chronic migraine patient with cerebral proliferative angiopathy who presented to our hospital in status epilepticus 2 d after his first dose of erenumab. Serial magnetic resonance imaging (MRI) studies demonstrated progressive areas of diffusion restriction including the brain tissue adjacent to the cerebral proliferative angiopathy, bilateral white matter and hippocampi. His 6-month post-presentation magnetic resonance imaging was notable for white matter injury, encephalomalacia surrounding cerebral proliferative angiopathy and bilateral hippocampal sclerosis. He remains clinically affected with residual symptoms, including refractory epilepsy and cognitive deficits. Conclusion The evidence presented in this case supports further investigation into potential deleterious side effects of erenumab in patients with compromised blood-brain barrier, such as individuals with intracranial vascular malformations.

scholarly journals T2 Relaxometry Using 3.0-Tesla Magnetic Resonance Imaging of the Brain in Early- and Late-Onset Restless Legs Syndrome

2014 ◽  
Vol 10 (3) ◽  
pp. 197 ◽  
Author(s):  
Hye-Jin Moon ◽  
Yongmin Chang ◽  
Yeong Seon Lee ◽  
Hee Jin Song ◽  
Hyuk Won Chang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Restless Legs Syndrome ◽  
Late Onset ◽  
Resonance Imaging ◽  
3.0 Tesla ◽  
T2 Relaxometry ◽  
Restless Legs ◽  
The Brain

Hippocampal sclerosis in temporal lobe epilepsy demonstrated by magnetic resonance imaging

1991 ◽  
Vol 29 (2) ◽  
pp. 175-182 ◽  
Author(s):  
Samuel F. Berkovic ◽  
Frederick Andermann ◽  
Andr� Olivier ◽  
Rom�o Ethier ◽  
Denis Melanson ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Hippocampal Sclerosis ◽  
Resonance Imaging

scholarly journals Magnetic Resonance Imaging and T2 Relaxometry of Cerebral White Matter and Hippocampus in Children Born Preterm

2003 ◽  
Vol 54 (6) ◽  
pp. 868-874 ◽  
Author(s):  
Laurence J Abernethy ◽  
Gillian Klafkowski ◽  
Lynda Foulder-Hughes ◽  
Richard W I Cooke
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Cerebral White Matter ◽  
Resonance Imaging ◽  
T2 Relaxometry

Magnetic Resonance Imaging Evidence of Hippocampal Sclerosis in Progression: A Case Report

Epilepsia ◽  
1994 ◽  
Vol 35 (6) ◽  
pp. 1332-1336 ◽  
Author(s):  
Virinder Nohria ◽  
Namsoo Lee ◽  
Robert D. Tien ◽  
E. Ralph Heinz ◽  
Jean S. Smith ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Magnetic Resonance ◽  
Hippocampal Sclerosis ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Evidence
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