Differences in plasma and peritoneal fluid proteomes identifies potential biomarkers associated with survival following strangulating small intestinal disease

2019 ◽  
Vol 51 (6) ◽  
pp. 727-732 ◽  
Author(s):  
D. Bardell ◽  
P. I. Milner ◽  
K. Goljanek‐Whysall ◽  
M. J. Peffers
Keyword(s):  
Peritoneal Fluid ◽  
Intestinal Disease ◽  
Small Intestinal ◽  
Small Intestinal Disease ◽  
Potential Biomarkers

Peritoneal Fluid Lactate Evaluation in Horses With Nonstrangulating Versus Strangulating Small Intestinal Disease

2018 ◽  
Vol 61 ◽  
pp. 18-21 ◽  
Author(s):  
Tara R. Shearer ◽  
Bo Norby ◽  
Elizabeth A. Carr
Keyword(s):  
Peritoneal Fluid ◽  
Intestinal Disease ◽  
Small Intestinal ◽  
Small Intestinal Disease

scholarly journals Proteomic Analysis of Equine Plasma and Peritoneal Fluid in Strangulating Small Intestinal Disease

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
David Bardell ◽  
Mandy J. Peffers ◽  
Peter Milner
Keyword(s):  
Proteomic Analysis ◽  
Peritoneal Fluid ◽  
Intestinal Disease ◽  
Equine Plasma ◽  
Small Intestinal ◽  
Small Intestinal Disease

Flow cytometric measurement of proliferation-associated nuclear antigen p105 and DNA content in immuno-proliferative small intestinal disease (IPSID)

1995 ◽  
Vol 58 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Taner Demirer ◽  
Ozden Uzunalimoglu ◽  
Tom Anderson ◽  
Susan M. Koethe ◽  
Patrick W. McFadden ◽  
...  
Keyword(s):  
Dna Content ◽  
Intestinal Disease ◽  
Nuclear Antigen ◽  
Flow Cytometric ◽  
Flow Cytometric Measurement ◽  
Small Intestinal ◽  
Small Intestinal Disease

Immunoproliferative small intestinal disease: An epidemiological, clinical and immunological analysis in 28 cases

1995 ◽  
Vol 108 (4) ◽  
pp. A277
Author(s):  
C. Chantar ◽  
J.L. Calleja ◽  
G. Cacho ◽  
JC Tardío
Keyword(s):  
Intestinal Disease ◽  
Immunological Analysis ◽  
Immunoproliferative Small Intestinal Disease ◽  
Small Intestinal ◽  
Small Intestinal Disease

Thromboembolism in Dogs with Protein-Losing Enteropathy with Non-Neoplastic Chronic Small Intestinal Disease

2017 ◽  
Vol 53 (3) ◽  
pp. 185-192 ◽  
Author(s):  
Ana M. L. Jacinto ◽  
Alison E. Ridyard ◽  
Itamar Aroch ◽  
Penny J. Watson ◽  
Linda R. Morrison ◽  
...  
Keyword(s):  
Serum Magnesium ◽  
Splenic Vein ◽  
Case Series ◽  
Intestinal Disease ◽  
Protein Losing Enteropathy ◽  
Vein Thrombosis ◽  
Increased Risk ◽  
Life Threatening ◽  
Small Intestinal ◽  
Small Intestinal Disease

ABSTRACT Dogs with protein-losing enteropathy (PLE) are suggested to be at increased risk of developing thromboembolic events. However, with some exceptions, there are very few reports of thromboembolism in such dogs. This multicentre retrospective observational study describes a case series of thromboembolism (TE) in eight dogs with PLE secondary to non-neoplastic, chronic small intestinal disease. Seven dogs had poorly controlled PLE when the thromboembolic event occurred. Pulmonary thromboembolism (PTE) occurred in six dogs, while one dog developed splenic vein thrombosis and another had concurrent splenic vein and aortic TE. Six dogs died, all with PTE. Antithrombin activity was decreased in one of two dogs in which it was measured. Serum cobalamin and folate concentrations were measured in three dogs and cobalamin was subnormal in all three. Serum magnesium, measured in two dogs, was low in both. Dogs with uncontrolled chronic small intestinal disease and PLE are at risk for developing serious life-threatening TE, mostly PTE.

Immunoproliferative small intestinal disease (IPSID): a model for mature B-cell neoplasms

Blood ◽  
2005 ◽  
Vol 105 (6) ◽  
pp. 2274-2280 ◽  
Author(s):  
Tahseen Al-Saleem ◽  
Hamid Al-Mondhiry
Keyword(s):  
B Cell ◽  
Plasma Cell ◽  
Heavy Chain ◽  
Early Stage ◽  
B Cell Lymphoma ◽  
Intestinal Disease ◽  
Molecular Features ◽  
Immunoproliferative Small Intestinal Disease ◽  
Small Intestinal ◽  
Small Intestinal Disease

AbstractImmunoproliferative small intestinal disease (IPSID) was recently added to the growing list of infectious pathogen-associated human lymphomas. Molecular and immunohistochemical studies demonstrated an association with Campylobacter jejuni. IPSID is a variant of the B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), which involves mainly the proximal small intestine resulting in malabsorption, diarrhea, and abdominal pain. Geographically, IPSID is most prevalent in the Middle East and Africa. IPSID lymphomas reveal excessive plasma cell differentiation and produce truncated α heavy chain proteins lacking the light chains as well as the first constant domain. The corresponding mRNA lacks the variable heavy chain (VH) and the constant heavy chain 1 (CH1) sequences and contains deletions as well as insertions of unknown origin. The encoding gene sequence reveals a deletion of V region and parts of CH1 domain. Cytogenetic studies demonstrated clonal rearrangements involving predominantly the heavy and light chain genes, including t(9;14) translocation involving the PAX5 gene. Early-stage IPSID responds to antibiotics (30%-70% complete remission). Most untreated IPSID patients progress to lymphoplasmacytic and immunoblastic lymphoma invading the intestinal wall and mesenteric lymph nodes, and may metastasize to a distant organ. IPSID lymphoma shares clinical, morphologic, and molecular features with MALT lymphoma, lymphoplasmacytic lymphoma, and plasma cell neoplasms.

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