Loop replacement design: a new way to improve potency of plant cystatins

FEBS Journal ◽  
2022 ◽  
Author(s):  
Karl J. Kunert ◽  
Priyen Pillay
Keyword(s):  
Author(s):  
N. Premkumar ◽  
K. Subhashini ◽  
G. Valarmathi ◽  
Jagadeesh Kumar ◽  
S Meganathan

2021 ◽  
Vol 10 (11) ◽  
pp. 2258
Author(s):  
Massimiliano Mosca ◽  
Silvio Caravelli ◽  
Emanuele Vocale ◽  
Simone Massimi ◽  
Davide Censoni ◽  
...  

Recently, the progress in techniques and in projecting new prosthetic designs has allowed increasing indications for total ankle replacement (TAR) as treatment for ankle osteoarthritis. This retrospective work comprehended 39 subjects aged between 47 and 79 years old. The patients, observed for at least 12 months (mean follow up of 18.2 ± 4.1 months), have been evaluated according to clinical and radiological parameters, both pre- and post-operatively. The AOFAS and VAS score significantly improved, respectively, from 46.2 ± 4.8 to 93.9 ± 4.1 and from 7.1 ± 1.1 to 0.7 ± 0.5 (p value < 0.05). At the final evaluation, the mean plantarflexion passed from 12.2° ± 2.3° to 18.1° ± 2.4° (p value < 0.05) and dorsiflexion from a pre-operative mean value of 8.7° ± 4.1° to 21.7° ± 5.4° post-operatively (p value < 0.05). This study found that this new total ankle replacement design is a safe and effective procedure for patients effected by end-stage ankle osteoarthritis. Improvements have been demonstrated in terms of range of motion, radiographic parameters and patient-reported outcomes. However, further studies are needed to assess the long-term performance of these prostheses.


2017 ◽  
Vol 42 ◽  
pp. 80-90 ◽  
Author(s):  
Ran S. Sopher ◽  
Andrew A. Amis ◽  
James D. Calder ◽  
Jonathan R.T. Jeffers

Author(s):  
Brian G. Sexton ◽  
Vinayagamoothy Sivakumar ◽  
Bryan A. McCabe ◽  
Richard Pugh
Keyword(s):  

2019 ◽  
Vol 34 (5) ◽  
pp. 965-973 ◽  
Author(s):  
Marcus Klutzny ◽  
Gurpal Singh ◽  
Rita Hameister ◽  
Gesine Goldau ◽  
Friedemann Awiszus ◽  
...  

2011 ◽  
Vol 3 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Hamdollah ESKANDARI ◽  
Kamyar KAZEMI

A field experiment was carried out in Ramhormoz, Iran during the 2008-2009 growing season to investigate the effects of different planting pattern of intercropping on environmental resource consumption and weed biomass. A randomized complete block design (RCBD) with three replications was employed to compare the treatments. Treatments included maize sole crop (M), cow pea sole crop (C), within row intercropping (I1), row intercropping (I2) and mix cropping (I3). The density of intercropping was according to replacement design (one maize replaced by three cow pea plants). The results showed that environmental resource consumption was significantly (P?0.05) affected by cropping system, where PAR interception, moisture and nutrients uptake were higher in intercropping systems compared to sole crop systems. Regarding to weed control, intercrops were more effective than sole crops and it was related to lower availability of environmental resources for weeds in intercropping systems.


1989 ◽  
Vol 35 (3) ◽  
pp. 388-390
Author(s):  
JANINE E. RHODES ◽  
TEDD A. BRANDON ◽  
ERIC J. GUILBEAU ◽  
GEORGE J. BJOTVEDT ◽  
ATUL SINGH ◽  
...  

1998 ◽  
Vol 88 (6) ◽  
pp. 943-948 ◽  
Author(s):  
Brian H. Cummins ◽  
James T. Robertson ◽  
Steven S. Gill

Object. To assess the effectiveness of Cummins' artificial cervical joint, the authors reviewed the cases of 20 patients in whom the joint had been placed. Methods. A review of patients' medical records and reexamination of 18 patients were performed. The review of the surgical experience with the implantation of movable stainless-steel joints in 20 patients treated for cervical myelopathy (16 patients), cervical radiculopathy (three patients), and severe pain (one patient) indicated that the procedure is safe and well tolerated and does preserve cervical joint motion in most patients over an extended period of observation. To date, adjacent segmental symptomatic degenerative changes leading to further surgical treatment have been avoided. The joint has been placed in patients with advanced congenital and acquired cervical fusion and has been demonstrated to be stable, mobile, and biomechanically and biochemically compatible; it has shown no subsidence into adjacent bone. Wear debris has not occurred. Conclusions. The use of stainless steel in the cervical spine appears to be suitable for this joint replacement design.


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