Investigation of superficial mycosis in cutaneous allergy patients using topical or systemic corticosteroids

2017 ◽  
Vol 56 (10) ◽  
pp. e194-e198
Author(s):  
Roseli S. de Freitas ◽  
Paula S. Neves ◽  
Cecília E. Charbel ◽  
Paulo R. Criado ◽  
Ricardo S. Nunes ◽  
...  
Keyword(s):  
Systemic Corticosteroids ◽  
Superficial Mycosis

A study on the antifungal susceptibility pattern of dermatophytes isolated in a tertiary care hospital

2017 ◽  
Vol 6 (05) ◽  
pp. 5379
Author(s):  
Vanathi Sabtharishi* ◽  
Radhika Katragadda ◽  
Thyagarajan Ravinder
Keyword(s):  
Tertiary Care Hospital ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
Antifungal Drugs ◽  
Dilution Method ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Superficial Mycosis ◽  
Broth Dilution ◽  
Common Infections

Recent years, due to increased usage of antifungal treatment worldwide, there is an increased chance of rising resistance among antifungal drugs too. Dermatophytic infections causes’ superficial mycosis and it affects skin, hair and nail. These infections are more common and antifungal drugs are used everywhere to treat those common infections. To conduct a study by determining the antifungal susceptibility pattern in dermatophytic isolates from patients attending dermatology OPD in a tertiary care hospital. A total of 217 samples like hair, nail and skin scrapings were obtained and isolation of dermatophytes was done. Antifungal susceptibility testing for dermatophytes was performed by micro broth dilution method. Antifungal drugs tested were Griseofulvin, Fluconazole, Itraconazole and Ketoconazole. Minimum inhibitory concentration for each drug for fungal isolates was tested and results studied. Fluconazole showed a higher MIC values in the range of 1-8µg/ml. Itraconazole showed the lowest MIC values by micro broth dilution method. Since there is limitation of standard guidelines and protocol, meticulous research must be conducted on effect of antifungals and derive at universally implementable guidelines.

scholarly journals Remdesivir and systemic corticosteroids for the treatment of COVID-19: A Bayesian re-analysis

2021 ◽  
Vol 104 ◽  
pp. 671-676
Author(s):  
Todd C. Lee ◽  
Emily G. McDonald ◽  
Guillaume Butler-Laporte ◽  
Luke B. Harrison ◽  
Matthew P. Cheng ◽  
...  
Keyword(s):  
Systemic Corticosteroids

scholarly journals Tocilizumab and Systemic Corticosteroids in the Management of COVID-19 Patients:A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Hadeel Alkofide ◽  
Abdullah Almohaizeie ◽  
Sara Almuhaini ◽  
Bashayer Alotaibi ◽  
Khalid M. Alkharfy
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Systemic Corticosteroids

scholarly journals Ocular adverse events associated with immune checkpoint inhibitors: a novel multidisciplinary management algorithm

2021 ◽  
Vol 13 ◽  
pp. 175883592199298
Author(s):  
Orthi Shahzad ◽  
Nicola Thompson ◽  
Gerry Clare ◽  
Sarah Welsh ◽  
Erika Damato ◽  
...  
Keyword(s):  
Adverse Events ◽  
Checkpoint Inhibitors ◽  
Case Reports ◽  
Case Series ◽  
Simple Algorithm ◽  
Cancer Therapeutics ◽  
Management Algorithm ◽  
Ocular Symptoms ◽  
Systemic Corticosteroids ◽  
Permanent Loss

Ocular immune-related adverse events (IrAEs) associated with use of checkpoint inhibitors (CPIs) in cancer therapeutics are relatively rare, occurring in approximately 1% of treated patients. Recognition and early intervention are essential because the degree of tissue damage may be disproportionate to the symptoms, and lack of appropriate treatment risks permanent loss of vision. International guidelines on managing ocular IrAEs provide limited advice only. Importantly, local interventions can be effective and may avoid the need for systemic corticosteroids, thereby permitting the continuation of CPIs. We present a single institution case series of eight affected patients managed by our multidisciplinary team. Consistent with previously published series and case reports, we identified anterior uveitis as the most common ocular IrAE associated with CPIs requiring intervention. Based on our experience, as well as published guidance, we generated a simple algorithm to assist clinicians efficiently manage patients developing ocular symptoms during treatment with CPIs. In addition, we make recommendations for optimising treatment of uveitis and address implications for ongoing CPI therapy.

Nonimmediate reactions to systemic corticosteroids suggest an immunological mechanism

Allergy ◽  
2005 ◽  
Vol 60 (5) ◽  
pp. 665-670 ◽  
Author(s):  
A. Padial ◽  
S. Posadas ◽  
J. Alvarez ◽  
M.-J. Torres ◽  
J. A. Alvarez ◽  
...  
Keyword(s):  
Immunological Mechanism ◽  
Systemic Corticosteroids
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