Evaluation of intralesional injection of bleomycin in the treatment of plantar warts: clinical and dermoscopic evaluation

Manal T. Barkat; Rasha T. A. Abdel-Aziz; Mervat S. Mohamed

doi:10.1111/ijd.14092

Evaluation of intralesional injection of bleomycin in the treatment of plantar warts: clinical and dermoscopic evaluation

International Journal of Dermatology ◽

10.1111/ijd.14092 ◽

2018 ◽

Vol 57 (12) ◽

pp. 1533-1537 ◽

Cited By ~ 4

Author(s):

Manal T. Barkat ◽

Rasha T. A. Abdel-Aziz ◽

Mervat S. Mohamed

Keyword(s):

Intralesional Injection ◽

Plantar Warts

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Intralesional injection of Candida albicans antigen versus measles, mumps, and rubella vaccine for treatment of plantar warts

Acta Dermatovenerologica Alpina Pannonica et Adriatica ◽

10.15570/actaapa.2021.1 ◽

2021 ◽

Vol 30 (1) ◽

Author(s):

Rania Mahmoud Rageh ◽

El-Sayed Shaaban Hewedy ◽

Doaa Salah Hegab

Keyword(s):

Candida Albicans ◽

Intralesional Injection ◽

Rubella Vaccine ◽

Plantar Warts

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Efficacy and safety of intralesional injection of vitamin D 3 versus tuberculin PPD in the treatment of plantar warts: A comparative controlled study

Journal of Cosmetic Dermatology ◽

10.1111/jocd.13712 ◽

2020 ◽

Author(s):

Nahla Elsayed Ghaly ◽

Amal Ahmad El‐Ashmawy ◽

Mai Abou Zeid ◽

Engi Seif E. Shaker

Keyword(s):

Vitamin D ◽

Controlled Study ◽

Intralesional Injection ◽

Efficacy And Safety ◽

Vitamin D 3 ◽

Plantar Warts

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Ionic Anti-Viral Intralesional Therapy in Plantar Warts

QJM ◽

10.1093/qjmed/hcab093.047 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Ghada Fathy Mohammed ◽

Ahmed Abd-Elfattah Afify ◽

Wessam Moustafa Abo Elmagd Abdel Latif

Keyword(s):

Normal Skin ◽

University Hospital ◽

Response To Treatment ◽

Alternative Form ◽

Steady Increase ◽

Intralesional Injection ◽

Significant Difference ◽

Group 2 ◽

Plantar Warts ◽

Group 1

Abstract Background Warts (verrucas) are an extremely common, benign, and usually self-limited skin disease. Their size ranges from a few millimetres to several centimetres. The normal skin lines are interrupted by skin coloured to brownish-grey proliferations, the diagnosis is established clinically; no supplementary histologic or virologic investigations are needed. Objective The aim of this two armed double blinded randomized clinical trial was to evaluate the clinical efficacy of intralesional combined digoxin and furosemide in the treatment of multiple planter warts. Methods This study included 40 patients with plantar warts, they were divided into 2 groups, 20 patients per group, the first group received intralesional normal saline, one injection session every week for maximum 5 injection sessions. The second group received intralesional combined digoxin and furosemide, one injection session every week for maximum 5 injection sessions. All the patients were recruited from the Dermatology outpatient clinic at Ain-Shams University Hospital and Shobra General Hospital during the period From July 2018 to July 2019. Results There was no statistically significant difference between the 2 studied groups as regard size of wart before treatment. While there was statistically significant difference between the 2 studied groups as regard size of wart after the 5th session. Also there was a steady increase in the response to treatment in group 2 showing an earlier response to treatment and most of patients with excellent and very good response to treatment after the 5th session. There was no statistically significant difference between the 2 studied groups as regard the number of warts before treatment. While there was statistically significant difference between the 2 studied groups as regard the number of warts after the 5th session. There was no statistically significant correlation between age, sex, disease duration and response to treatment (as regard reduction in number of warts) after the 5th session in group 2. While in group 1 there was no reduction in number of warts after the 5th session. There was a statistically significant difference between the number of warts before and after receiving the active treatment in group 1, in group 2 and for both groups together (all patients). Conclusion We concluded from this study that intralesional injection of combined digoxin and furosemide offers effective alternative form of treatment for plantar warts in adults. It is inexpensive and safe to treat plantar warts.

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