scholarly journals Intralesional injection of Candida albicans antigen versus measles, mumps, and rubella vaccine for treatment of plantar warts

2021 ◽  
Vol 30 (1) ◽  
Author(s):  
Rania Mahmoud Rageh ◽  
El-Sayed Shaaban Hewedy ◽  
Doaa Salah Hegab
Keyword(s):  
Candida Albicans ◽  
Intralesional Injection ◽  
Rubella Vaccine ◽  
Plantar Warts

Intralesional Vitamin D Injection May Be an Effective Treatment Option for Warts

2015 ◽  
Vol 20 (2) ◽  
pp. 118-122 ◽  
Author(s):  
Habibullah Aktaş ◽  
Can Ergin ◽  
Betül Demir ◽  
Özlem Ekiz
Keyword(s):  
Vitamin D ◽  
Candida Albicans ◽  
Adverse Effects ◽  
Effective Treatment ◽  
Treatment Option ◽  
Complete Resolution ◽  
Efficacy And Safety ◽  
Effective Treatment Option ◽  
Rubella Vaccine ◽  
Plantar Warts

Background: Plantar warts are typically resistant to treatment. In recent years, treatments have included administration of intralesional tuberculin; measles, mumps, rubella vaccine; and Candida albicans antigen immunotherapy. To the best of our knowledge, there are no reports of intralesional vitamin D administration for the treatment of warts. Aim: To evaluate the efficacy and safety of intralesional vitamin D treatment for plantar warts. Methods: Twenty patients with single or multiple plantar warts were included in this study. Vitamin D3 (0.2 mL, 7.5 mg/mL) was injected into the base of the warts after prilocaine (0.1 mL, 20 mg/mL) injection. A maximum of 5 warts were treated in 1 session, with at maximum 2 injections performed at 4-week intervals. Results: In total, 16 of 20 patients (80%) showed complete resolution of warts, and 1 patient showed partial resolution. Three patients failed to show any response. No recurrence or serious adverse effects were observed. Conclusion: Intralesional vitamin D3 may be an effective treatment option for warts.

scholarly journals Evaluation of the efficacy of a combination – measles, mumps and rubella vaccine in the treatment of plantar warts

2013 ◽  
Vol 4 (4) ◽  
pp. 463-467 ◽  
Author(s):  
Nagat Sobhy Mohamad ◽  
Fayrouz Badran ◽  
Esraa Yakout
Keyword(s):  
Rubella Vaccine ◽  
Plantar Warts

Ionic Anti-Viral Intralesional Therapy in Plantar Warts

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ghada Fathy Mohammed ◽  
Ahmed Abd-Elfattah Afify ◽  
Wessam Moustafa Abo Elmagd Abdel Latif
Keyword(s):  
Normal Skin ◽  
University Hospital ◽  
Response To Treatment ◽  
Alternative Form ◽  
Steady Increase ◽  
Intralesional Injection ◽  
Significant Difference ◽  
Group 2 ◽  
Plantar Warts ◽  
Group 1

Abstract Background Warts (verrucas) are an extremely common, benign, and usually self-limited skin disease. Their size ranges from a few millimetres to several centimetres. The normal skin lines are interrupted by skin coloured to brownish-grey proliferations, the diagnosis is established clinically; no supplementary histologic or virologic investigations are needed. Objective The aim of this two armed double blinded randomized clinical trial was to evaluate the clinical efficacy of intralesional combined digoxin and furosemide in the treatment of multiple planter warts. Methods This study included 40 patients with plantar warts, they were divided into 2 groups, 20 patients per group, the first group received intralesional normal saline, one injection session every week for maximum 5 injection sessions. The second group received intralesional combined digoxin and furosemide, one injection session every week for maximum 5 injection sessions. All the patients were recruited from the Dermatology outpatient clinic at Ain-Shams University Hospital and Shobra General Hospital during the period From July 2018 to July 2019. Results There was no statistically significant difference between the 2 studied groups as regard size of wart before treatment. While there was statistically significant difference between the 2 studied groups as regard size of wart after the 5th session. Also there was a steady increase in the response to treatment in group 2 showing an earlier response to treatment and most of patients with excellent and very good response to treatment after the 5th session. There was no statistically significant difference between the 2 studied groups as regard the number of warts before treatment. While there was statistically significant difference between the 2 studied groups as regard the number of warts after the 5th session. There was no statistically significant correlation between age, sex, disease duration and response to treatment (as regard reduction in number of warts) after the 5th session in group 2. While in group 1 there was no reduction in number of warts after the 5th session. There was a statistically significant difference between the number of warts before and after receiving the active treatment in group 1, in group 2 and for both groups together (all patients). Conclusion We concluded from this study that intralesional injection of combined digoxin and furosemide offers effective alternative form of treatment for plantar warts in adults. It is inexpensive and safe to treat plantar warts.

Evaluation of intralesional injection of bleomycin in the treatment of plantar warts: clinical and dermoscopic evaluation

2018 ◽  
Vol 57 (12) ◽  
pp. 1533-1537 ◽  
Author(s):  
Manal T. Barkat ◽  
Rasha T. A. Abdel-Aziz ◽  
Mervat S. Mohamed
Keyword(s):  
Intralesional Injection ◽  
Plantar Warts

A comparative study of intralesional injection of Candida albicans antigen, bleomycin and 5-fluorouracil for treatment of plane warts

2019 ◽  
pp. 1-6 ◽  
Author(s):  
Abeer Abd Elhakam Hodeib ◽  
Basma Gamal Al-Sharkawy ◽  
Doaa Salah Hegab ◽  
Raghda Ahmed Zaki Talaat
Keyword(s):  
Candida Albicans ◽  
Comparative Study ◽  
Intralesional Injection

Intralesional injection of purified protein derivatives versus zinc sulfate 2% in recalcitrant palmar and/or plantar warts

2016 ◽  
Vol 13 (3) ◽  
pp. 151-158 ◽  
Author(s):  
Alaa E.A. Moubasher ◽  
Osama M. Hassan ◽  
Eman M.K. Youssef ◽  
Marwa M.A. Sabek
Keyword(s):  
Zinc Sulfate ◽  
Intralesional Injection ◽  
Plantar Warts

Intralesional Measles, Mumps, and Rubella Vaccine Versus Intralesional Candida Antigen in the Treatment of Common and Plantar Warts

2021 ◽  
pp. 120347542199113
Author(s):  
Ahmad Nofal ◽  
Reda Ezz El-arab ◽  
Mohamed Nasr ◽  
Rania Alakad
Keyword(s):  
Therapeutic Response ◽  
Comparable Efficacy ◽  
Efficacy And Safety ◽  
Mmr Vaccine ◽  
Rubella Vaccine ◽  
Complete Clearance ◽  
Common Warts ◽  
The Difference ◽  
Plantar Warts

Background Intralesional immunotherapy has been effectively used in the treatment of warts; however, comparative studies between different antigens are limited. Objective To evaluate the efficacy and safety of intralesional measles, mumps, and rubella (MMR) vaccine compared with intralesional Candida antigen for the treatment of multiple common and plantar warts. Methods Sixty-eight adult patients with multiple common and plantar warts were randomly assigned into two groups, each containing 34 patients. The first group received intralesional MMR vaccine, while the second group received intralesional Candida antigen. Each treatment was injected into the largest wart at 2-week intervals until complete clearance or for a maximum of 5 sessions. Results The overall therapeutic response was higher in the Candida antigen group (73.5%) compared with the MMR group (67.7%); however, the difference was not statistically significant. Complete clearance of common warts was higher in the Candida antigen group, while that of plantar warts was higher in the MMR group. Adverse effects were transient and well tolerated in both groups. No recurrence was detected during the 6-month follow-up period. Conclusion Intralesional MMR and intralesional Candida antigen showed comparable efficacy and safety in the treatment of common and plantar warts.

scholarly journals Candida albicans Immunotherapy for Verrucae Plantaris

2015 ◽  
Vol 105 (5) ◽  
pp. 395-400 ◽  
Author(s):  
Tracey C. Vlahovic ◽  
Samuel Spadone ◽  
S. Patrick Dunn ◽  
Tara Fussell ◽  
Ian Hersh ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Treatment Process ◽  
Viral Disease ◽  
High Recurrence Rate ◽  
Intralesional Injection ◽  
Papilloma Virus ◽  
Intralesional Injections ◽  
Lost To Follow Up ◽  
Immunogenic Response

Background Verrucae plantaris is a viral disease caused by human papilloma virus that is commonly seen in the office setting and is often challenging to treat owing to its high recurrence rate and recalcitrant profile. Candida albicans intralesional injections have been hypothesized to incite an immunogenic response toward the virus. Methods We report on the immunotherapeutic effect of intralesional injection of C albicans into plantar verrucae with a retrospective medical record analysis of 80 patients. Using a luer-lock syringe, 0.1 to 0.3 mL of C albicans antigen was injected into either the first known lesion or the largest lesion. Results The success rate of intralesional C albicans, defined as total clearance of the lesion, was 65%, which may be underestimated because patients lost to follow-up were included in the 35% failure rate. It was also found that female patients with a previous tissue-destructive treatment process were more than four times more likely to respond to C albicans therapy, whereas this effect was less pronounced in the male patient population. Conclusions These results indicate that a series of intralesional injections of C albicans is an effective and efficient method of treatment for verrucae plantaris.

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