scholarly journals Seasonal impact on surgical site infections and wound healing disturbance in carpal tunnel surgery: A retrospective cohort study

2021 ◽  
Author(s):  
Stefan Mathias Froschauer ◽  
Wolfgang Raher ◽  
Matthias Holzbauer ◽  
Elizabeth Brett ◽  
Oskar Kwasny ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cohort Study ◽  
Carpal Tunnel ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Surgical Site Infections ◽  
Carpal Tunnel Surgery ◽  
Seasonal Impact

scholarly journals Selective Decontamination of the Digestive Tract to Prevent Postoperative Pneumonia and Anastomotic Leakage after Esophagectomy: A Retrospective Cohort Study

Antibiotics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 43
Author(s):  
Robin Janssen ◽  
Frans Van Workum ◽  
Nikolaj Baranov ◽  
Harmen Blok ◽  
Jaap ten Oever ◽  
...  
Keyword(s):  
Cohort Study ◽  
Anastomotic Leakage ◽  
Digestive Tract ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Protective Factor ◽  
Gastrointestinal Surgery ◽  
Surgical Site Infections ◽  
Selective Decontamination ◽  
Postoperative Pneumonia

Infectious complications occur frequently after esophagectomy. Selective decontamination of the digestive tract (SDD) has been shown to reduce postoperative infections and anastomotic leakage in gastrointestinal surgery, but robust evidence for esophageal surgery is lacking. The aim was to evaluate the association between SDD and pneumonia, surgical-site infections (SSIs), anastomotic leakage, and 1-year mortality after esophagectomy. A retrospective cohort study was conducted in patients undergoing Ivor Lewis esophagectomy in four Dutch hospitals between 2012 and 2018. Two hospitals used SDD perioperatively and two did not. SDD consisted of an oral paste and suspension (containing amphotericin B, colistin, and tobramycin). The primary outcomes were 30-day postoperative pneumonia and SSIs. Secondary outcomes were anastomotic leakage and 1-year mortality. Logistic regression analyses were performed to determine the association between SDD and the relevant outcomes (odds ratio (OR)). A total of 496 patients were included, of whom 179 received SDD perioperatively and the other 317 patients did not receive SDD. Patients who received SDD were less likely to develop postoperative pneumonia (20.1% vs. 36.9%, p < 0.001) and anastomotic leakage (10.6% vs. 19.9%, p = 0.008). Multivariate analysis showed that SDD is an independent protective factor for postoperative pneumonia (OR 0.40, 95% CI 0.23–0.67, p < 0.001) and anastomotic leakage (OR 0.46, 95% CI 0.26–0.84, p = 0.011). Use of perioperative SDD seems to be associated with a lower risk of pneumonia and anastomotic leakage after esophagectomy.

scholarly journals Associated factors with surgical site infections after hepatectomy: Predictions and countermeasures by a retrospective cohort study

2014 ◽  
Vol 12 (4) ◽  
pp. 310-314 ◽  
Author(s):  
Atsushi Nanashima ◽  
Junichi Arai ◽  
Syousaburo Oyama ◽  
Mitsutoshi Ishii ◽  
Takafumi Abo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Associated Factors ◽  
Surgical Site Infections

scholarly journals Effectiveness of topical vancomycin in the prevention of spinal surgical site infections: a retrospective cohort study

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Rawan T. Tafish ◽  
Ahmed F. Alkhaldi ◽  
Anouar Bourghli ◽  
Turki A. Althunian
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Propensity Score Analysis ◽  
Surgical Site Infections ◽  
Skin Closure ◽  
Confounding By Indication ◽  
Score Analysis ◽  
Vancomycin Powder

Abstract Background The risk of surgical site infections (SSIs), particularly methicillin-resistant Staphylococcus aureus (MRSA) SSIs, after spinal surgeries is one of the most daunting experiences to patients and surgeons. Some authors suggest applying vancomycin powder on the wound before skin closure to minimize the risk of SSIs; however, this practice is not supported by well-established evidence. This study sought to assess the effectiveness of topical (i.e. intra-wound) vancomycin in minimizing the risk of SSIs in patients who underwent spinal surgeries at a Saudi hospital. Methods A retrospective cohort study was conducted using the hospital database. Patients who underwent spinal surgeries from the period of 09/2013 to 09/2019 were included and followed up (observed from the time of the surgery) to 30 days (surgeries without implants) or 90 days (with implants). The odds ratio (OR) of the primary outcome between vancomycin treated versus non-treated patients was estimated using a logistic regression model adjusting for the measured confounders. A sensitivity analysis was conducted using propensity score analysis (inverse probability of treatment weighting [IPTW] with stabilized weights) to control for confounding by indication. All study analyses were completed using RStudio Version 1.2.5033. Results We included 81 vancomycin treated vs. 375 untreated patients with 28 infections (8/81 vs. 20/375; respectively). The adjusted OR of SSIs between the two groups was 0.40 (95% confidence interval [CI] 0.11 to 1.34). The result of the propensity score analysis was consistent (OR: 0.97 [95% CI 0.35 to 2.68]). Conclusions We could not find a lower association of SSIs with intra-wound vancomycin in patients who underwent spinal surgeries. Further studies are needed to assess benefits of using topical vancomycin for this indication vs. the risk of antimicrobial resistance.

scholarly journals Effectiveness of Topical Vancomycin in the Prevention of Spinal Surgical Site Infections: A Retrospective Cohort Study

2021 ◽  
pp. 33
Author(s):  
Rawan Tafish
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Propensity Score Analysis ◽  
Surgical Site Infections ◽  
Skin Closure ◽  
Multicenter Studies ◽  
Score Analysis ◽  
Vancomycin Powder

Introduction: The risk of surgical site infections (SSIs), particularly methicillin-resistant Staphylococcus aureus (MRSA) SSIs, post spinal surgeries is one of the most daunting experiences to patients and surgeons. In some practices, vancomycin powder is applied directly on the wound before skin closure to minimize the risk of SSIs; however, this practice is not supported by well-established evidence. This study sought to assess the effectiveness of topical (intra-wound) vancomycin in minimizing the risk of SSIs in patients who underwent spinal surgeries at a private Saudi hospital. Methodology: A retrospective cohort study was conducted using the hospital database. Patients who underwent spinal surgeries between September 2013 and September 2019 were included and followed-up for up to 30 (for surgeries without implantation) or 90 (for surgeries with implantation) days. The odds ratio (OR) of the first SSI observed in the follow-up period between vancomycin users versus nonusers was estimated using logistic regression adjusting for the measured confounders. A sensitivity analysis was conducted using a propensity score analysis. Result: We included 81 vancomycin users versus 375 nonusers with 28 infections. The adjusted OR of SSIs between the two groups was 0.40 (95% confidence interval [CI] 0.11–1.34). The result of the propensity score analysis was consistent (OR: 0.97 [95% CI 0.35–2.68]). Conclusion: We could not find a lower association of SSIs with intra-wound vancomycin in patients who underwent spinal surgeries. Conducting larger multicenter studies would add more emphasis to the findings of this study. 

scholarly journals Risk Factors of Surgical Site Infections after Colon Surgery in Community Hospitals: A Multicenter Retrospective Cohort Study

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S651-S651
Author(s):  
Maojun Ge ◽  
Arthur W Baker ◽  
Sarah S Lewis ◽  
Rebekah W Moehring ◽  
Daniel Sexton ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Surgical Site Infections ◽  
Colon Surgery ◽  
Community Hospitals
Sign in / Sign up

Export Citation Format

Share Document