Plasma Fibrinogen and Erythrocyte Sedimentation Rate in Myocardial Infarction

2009 ◽  
Vol 156 (5) ◽  
pp. 351-360 ◽  
Author(s):  
T. HOLGER-MADSEN
Keyword(s):  
Myocardial Infarction ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Plasma Fibrinogen ◽  
Erythrocyte Sedimentation

Predictive markers of severity of postinfarction in patients of working age who have had Q-myocardial infarction

2020 ◽  
pp. 76-80
Author(s):  
G. V. Babushkina ◽  
S. V. Permyakova ◽  
A. M. Gubaeva
Keyword(s):  
Myocardial Infarction ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Left Ventricular ◽  
Blood Leukocytes ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Primary Endpoints ◽  
Working Age ◽  
Relationship Of

The aim of the study was to determine the prognostic criteria for the severity of postinfarction (within 12 months) course in patients of working age who underwent Q-myocardial infarction (Q-MI), having studied the relationship of significant biochemical parameters with hemodynamic parameters and primary endpoints.Materials and methods. We observed 104 male patients of working age who were admitted to the hospital with primary Q-MI, receiving rosuvastatin at a dose of 40 mg and atorvastatin at a dose of 80 mg as part of complex therapy. Results. A direct correlation was found between the baseline parameters of C-reactive protein (CRP), aldosterone, creatinine phosphokinase, erythrocyte sedimentation rate, leukocytes, left ventricular myocardial mass (LVMM) and the primary endpoints studied during 12 months of observation in patients of working age who underwent Q-myocardial infarction. Conclusions. Thus, the baseline level of CRP, aldosterone, creatinine phosphokinase, erythrocyte sedimentation rate, blood leukocytes and LVMM were the prognostic markers of the severity of postinfarction course in patients of working age who underwent Q-MI.

scholarly journals Bloody jello: Colloidal physics states acanthocyte sedimentation rate as a diagnostic biomarker for neuroacanthocytosis

2020 ◽  
Author(s):  
Alexis Darras ◽  
Kevin Peikert ◽  
Antonia Rabe ◽  
François Yaya ◽  
Greta Simionato ◽  
...  
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Neurodegenerative Disorders ◽  
Diagnostic Marker ◽  
Plasma Fibrinogen ◽  
Diagnostic Biomarker ◽  
The Core ◽  
Erythrocyte Sedimentation ◽  
Colloidal Physics

ABSTRACTChorea-acanthocytosis and McLeod syndrome are the core diseases among the group of rare neurodegenerative disorders called neuroacanthocytosis syndrome (NAS). NAS patients have irregularly spiky erythrocytes, so-called acanthocytes. Their detection is a crucial but error-prone parameter in the diagnosis of NAS, often leading to misdiagnosis. Based on the standard Westergren method, we show that the acanthocyte sedimentation rate (ASR) with a two-hour read-out is significantly prolonged in Chorea-acanthocytosis and McLeod syndrome without overlap compared to the erythrocyte sedimentation rate (ESR) of controls. Thus, the ASR/ESR is a clear, robust and easily obtained diagnostic marker. Mechanistically, through modern colloidal physics, we show that acanthocyte aggregation and plasma fibrinogen levels slow down the sedimentation. This study is also a hallmark of the physical view of the erythrocyte sedimentation by describing anticoagulated blood in stasis as a percolating gel, allowing the application of colloidal physics theory.

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