scholarly journals No Evidence of HTLV-1 Infection in Japanese Multiple Sclerosis Patients in Polymerase Chain Reaction

1989 ◽  
Vol 80 (11) ◽  
pp. 1017-1020 ◽  
Author(s):  
Toshiki Watanabe ◽  
Yuzo Iwasaki ◽  
Kunio Tashiro ◽  
Mitsuaki Yoshida
Keyword(s):  
Multiple Sclerosis ◽  
Polymerase Chain Reaction ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Multiple Sclerosis Patients

Failure to Detect Measles Virus Rna, by Reverse Transcription-Polymerase Chain Reaction, in Peripheral Blood Leucocytes of Patients with Multiple Sclerosis

1996 ◽  
Vol 1 (4) ◽  
pp. 204-206 ◽  
Author(s):  
B. Brankin ◽  
M. Osman ◽  
L. Herlihy ◽  
S.A. Hawkins ◽  
S.L. Cosby
Keyword(s):  
Multiple Sclerosis ◽  
Polymerase Chain Reaction ◽  
Reverse Transcription ◽  
Peripheral Blood ◽  
Measles Virus ◽  
Chain Reaction ◽  
Specific Primers ◽  
Polymerase Chain ◽  
Multiple Sclerosis Patients ◽  
Peripheral Blood Leucocytes

We have examined peripheral blood leucocytes (PBLs) from 17 multiple sclerosis patients, two patients with rheumatoid arthritis, one case of acute childhood measles and one case of subacute sclerosing panencephalitis, as well as 19 healthy adult controls for measles virus (MV) RNA, by the technique of reverse transcription-polymerase chain reaction. MV nucleocapsid gene specific primers were used to amplify all PBL-derived cDNA samples. These proved to be negative with the exception of the sample derived from the acute measles case. Selected cases were examined further, using fusion gene and matrix gene specific primers. MV RNA could not be detected.

Detection of Herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction

1996 ◽  
Vol 2 (4) ◽  
pp. 249-258 ◽  
Author(s):  
Virginia J Sanders ◽  
Stephen Felisan ◽  
Aimee Waddell ◽  
Wallace W Tourtellotte
Keyword(s):  
Multiple Sclerosis ◽  
Polymerase Chain Reaction ◽  
Brain Tissue ◽  
Chain Reaction ◽  
Polymerase Chain

scholarly journals Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis

2019 ◽  
Vol 6 (10) ◽  
Author(s):  
Cléa Melenotte ◽  
Ahmed Loukil ◽  
Audrey Rico ◽  
Hubert Lepidi ◽  
Didier Raoult
Keyword(s):  
Multiple Sclerosis ◽  
Polymerase Chain Reaction ◽  
Blood Culture ◽  
Chain Reaction ◽  
Serological Tests ◽  
Specific Polymerase Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Polymerase Chain ◽  
Culture Negative

Abstract A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii–specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of removed cardiac valves because blood culture–negative endocarditis can be pauci-symptomatic, and serological tests can be negative in cases of immunosuppression.

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