Effects of dietary caffeine on growth, body composition, somatic indexes, and cerebral distribution of acetyl-cholinesterase and nitric oxide synthase in gilthead sea bream (Sparus aurata), reared in winter temperature

2008 ◽  
Vol 14 (5) ◽  
pp. 405-415 ◽  
Author(s):  
S. CHATZIFOTIS ◽  
F. KOKOU ◽  
K. AMPATZIS ◽  
I.E. PAPADAKIS ◽  
P. DIVANACH ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Body Composition ◽  
Nitric Oxide Synthase ◽  
Sparus Aurata ◽  
Winter Temperature ◽  
Gilthead Sea Bream ◽  
Sea Bream ◽  
Acetyl Cholinesterase ◽  
Oxide Synthase

scholarly journals Curcumin Reverses the Scopolomine-induced Cognitive Impairment by iNOS and Acetylcholinesterase Inhibition in Rodent Model of Schizophrenia

2020 ◽  
pp. 122-128
Author(s):  
Henna Khan ◽  
AMIT CHAUDHARY ◽  
RASHID ALI KHAN ◽  
WAZID ALI
Keyword(s):  
Nitric Oxide ◽  
Cognitive Impairment ◽  
Nitric Oxide Synthase ◽  
Elevated Plus Maze ◽  
Acetylcholinesterase Inhibition ◽  
Control Group ◽  
Acetyl Cholinesterase ◽  
Amnesic Effect ◽  
Plus Maze ◽  
Oxide Synthase

Schizophrenia is a severe neuro-developmental psychiatric disorder. Curcumin is a polyphenolic compound extracted from turmeric. It is known for its antioxidant, anti-inflammatory, neuroprotective, and precognitive properties. The purpose of the current study was to evaluate the role of curcumin in scopolamine induced cognitive impairment in animal model of schizophrenia. The elevated plus-maze test was utilised to study the curcumin effect on learning and memory. Curcumin (100 mg/kg, i.p.) was administered daily for 28 days in animals. Behavioural tests such as transfer latency (TL) and spontaneous alteration behaviour was assessed after the last dose of curcumin on the 28th day, followed by biochemical estimations. Present study reported that curcumin showed anti-amnesic effect in animal models of cognitive impairment of schizophrenia. Curcumin reduced the TL compared to toxic control group (scopolamine per se) (P <0.001) in elevated plus maze. In spontaneous alteration behaviour test, curcumin significantly increased percentage alteration and possible alteration as compared to toxic control group (P <0.001). A significant change in acetyl cholinesterase activity, nitrate and oxidative parameters was observed, thus, confirming its anti acetyl cholinesterase, NOS (nitric oxide synthase) inhibition and antioxidant properties (P <0.05). The present study put forward the claim of curcumin as a new and safer therapeutic alternative for the treatment of cognitive impairment in Schizophrenia. The underlying mechanism of this potential effect may be related to anticholinesterase and nitric oxide synthase inhibition activity of curcumin. Further research is warranted for confirming the suggested pathways accountable for memory alleviating effects of curcumin in Schizophrenia.

The effects of long-day photoperiod on growth, body composition and skin colour in immature gilthead sea bream (Sparus aurata L.)

2004 ◽  
Vol 35 (13) ◽  
pp. 1207-1212 ◽  
Author(s):  
Rafael Gines ◽  
Juan Manuel Afonso ◽  
Anastasio Arguello ◽  
Maria Jesus Zamorano ◽  
Juan Luis Lopez
Keyword(s):  
Body Composition ◽  
Sparus Aurata ◽  
Gilthead Sea Bream ◽  
Skin Colour ◽  
Sea Bream ◽  
Long Day

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

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