Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity

2005 ◽  
Vol 154 (1) ◽  
pp. 90-98 ◽  
Author(s):  
N. Oyama ◽  
J.F. Setterfield ◽  
A.M. Powell ◽  
Y. Sakuma-Oyama ◽  
S. Albert ◽  
...  
Keyword(s):  
Disease Severity ◽  
Bullous Pemphigoid ◽  
Mucous Membrane ◽  
Class Ii ◽  
Hla Class Ii ◽  
Mucous Membrane Pemphigoid ◽  
Bullous Pemphigoid Antigen ◽  
Extracellular Domains ◽  
Hla Class Ii Alleles

Association of HLA Class II Alleles with Disease Severity and Treatment Response in Iranian Patients with Myasthenia Gravis

2021 ◽  
pp. 1-3
Author(s):  
Farnaz Sinaei ◽  
Farzad Fatehi ◽  
Shahram Oveis Gharan ◽  
Soroush Ehsan ◽  
Koorosh Kamali ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Treatment Response ◽  
Disease Severity ◽  
Class Ii ◽  
Hla Class Ii ◽  
Number Of Patients ◽  
Different Populations ◽  
Encoding Genes ◽  
Hla Class Ii Alleles

Myasthenia gravis is an autoimmune neuromuscular disease with a multifactorial etiology. A major part of the genetic susceptibility belongs to the HLA encoding genes. In this study, we investigated the role of HLA class II polymorphism in disease severity, and treatment response. In our 146 patients, 15 DRB1, 7 DQA1, and 9 DQB1 alleles, and 19 haplotypes were found. Adjusted p-values did not show any significant associations between these loci, disease severity and treatment outcome. Further studies in different populations with a larger number of patients are needed to determine the exact contribution of HLA class II alleles to MG prognosis.

MHC and malaria: the relationship between HLA class II alleles and immune responses to Plasmodium falciprum

1992 ◽  
Vol 4 (9) ◽  
pp. 1055-1063 ◽  
Author(s):  
E. M. Riley ◽  
O. Olerup ◽  
S. Bennett ◽  
P. Rowe ◽  
S. J. Allen ◽  
...  
Keyword(s):  
Immune Responses ◽  
Class Ii ◽  
Hla Class Ii ◽  
The Relationship ◽  
Hla Class Ii Alleles

Susceptibility to IDDM in a Chinese Population: Role of HLA Class II Alleles

Diabetes ◽  
1992 ◽  
Vol 41 (8) ◽  
pp. 914-919 ◽  
Author(s):  
M. A. Penny ◽  
D. Jenkins ◽  
C. H. Mijovic ◽  
K. H. Jacobs ◽  
D. A. Cavan ◽  
...  
Keyword(s):  
Chinese Population ◽  
Class Ii ◽  
Hla Class Ii ◽  
Hla Class Ii Alleles

scholarly journals CD4+ T-cell alloreactivity toward mismatched HLA class II alleles early after double umbilical cord blood transplantation

Blood ◽  
2016 ◽  
Vol 128 (17) ◽  
pp. 2165-2174 ◽  
Author(s):  
Cor H. J. Lamers ◽  
Rebecca Wijers ◽  
Cornelis A. M. van Bergen ◽  
Judith A. E. Somers ◽  
Eric Braakman ◽  
...  
Keyword(s):  
T Cells ◽  
Cord Blood Transplantation ◽  
Class Ii ◽  
Hla Class Ii ◽  
Effector T Cells ◽  
Cd4 T Cell ◽  
Blood Transplantation ◽  
Key Points ◽  
Allele Specific ◽  
Hla Class Ii Alleles

Key Points Graft-versus-graft alloreactivity after dUCBT involves recognition of mismatched HLA class II alleles by allele-specific CD4+ effector T cells. Alloreactive donor CD4+ T cells may recognize recipient leukemia if mismatched for individual HLA class II alleles.

Association of HLA class II alleles with hepatitis C virus clearance and persistence in thalassemia patients from Iran

2015 ◽  
Vol 87 (9) ◽  
pp. 1565-1572 ◽  
Author(s):  
Katayoun Samimi-Rad ◽  
Farzin Sadeghi ◽  
Aliakbar Amirzargar ◽  
Mohamad Reza Eshraghian ◽  
Seyed-Moayed Alavian ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Class Ii ◽  
Hla Class Ii ◽  
Virus Clearance ◽  
Hla Class Ii Alleles

scholarly journals HLA class II alleles associated with infection by HPV16 in cervical cancerin situ

2001 ◽  
Vol 93 (6) ◽  
pp. 817-822 ◽  
Author(s):  
Anna H. Beskow ◽  
Agnetha M. Josefsson ◽  
Ulf B. Gyllensten
Keyword(s):  
Class Ii ◽  
Hla Class Ii ◽  
Hla Class Ii Alleles
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