Desmin and myogenin reactivity in mesenchymal chondrosarcoma: a potential diagnostic pitfall

2006 ◽  
Vol 48 (2) ◽  
pp. 201-203 ◽  
Author(s):  
C Gengler ◽  
I Letovanec ◽  
L Taminelli ◽  
J F Egger ◽  
L Guillou
2013 ◽  
Vol 4 (3) ◽  
pp. 152-155
Author(s):  
Asif Loya ◽  
Imrana Tanvir ◽  
Sabiha Riaz ◽  
Haseeb Ahmed Khan ◽  
Khubaib Shahid

ABSTRACT Mesenchymal chondrosarcoma is a rare aggressive neoplasm affecting the bones of young adults. It also arises extraskeletal in CNS, so ft tissu e and other o rgans. Intrac ran ial and those that originate from the dura mater are very rare. These tumors constitute an entirely different entity from classical chondrosarcoma. These are characterized by a bimorphic histological pattern composed of highly undifferentiated small round to oval cells and islands of well-differentiated hyaline cartilage with calcification and ossification. We hereby report a case of mesenchymal chondrosarcoma arising from the right tentorium cerebelli in a 40-year-old man with symptoms of mass effect. Histological examination demonstrated sheets of round to oval cells with islands of hyaline cartilage. The diagnosis of mesenchymal chondrosarcoma was made after a thorough microsco pic assessmen t. T umo r in add ition to cellular component also revealed a prominent cartilaginous component. We hereby discuss the morphological features of mesenchymal chondrosarcoma arising in the CNS, the differential diagnoses of small round-cell tumors within the CNS, and the differentiating features of mesenchymal chondrosarcoma from the other differential diagnoses. How to cite this article Tanvir I, Riaz S, Khan HA, Loya A, Shahid K. Mesenchymal Chondrosarcoma arising in the Central Nervous System: A Diagnostic Pitfall. Int J Head Neck Surg 2013;4(3):152-155.


BMJ ◽  
1974 ◽  
Vol 1 (5901) ◽  
pp. 248-248
Author(s):  
G. A. Jackson ◽  
P. M. Fea
Keyword(s):  

2021 ◽  
pp. 004947552110206
Author(s):  
Prasad Dange ◽  
Ankesh Gupta ◽  
Richa Juneja ◽  
Renu Saxena

Long-standing moderate to marked splenomegaly suggests several differential diagnoses, both haematological and infectious, particularly leishmaniasis and malaria in endemic areas. Non-infectious causes may be missed in these regions, especially if pitfalls of serological testing are not considered. Careful patient evaluation is necessary to arrive at the correct diagnosis. We report a case of a young male whose hereditary spherocytosis was initially missed because of RK-39 positivity, splenomegaly and the fact that he hailed from an endemic region.


Author(s):  
Saloni Naresh Shah ◽  
Ashok Parameswaran ◽  
Prasanna Kumar Reddy

AbstractExtraskeletal mesenchymal chondrosarcoma (ESMC) metastasizing to the pancreas in isolation is a rare occurrence. We report a 49-year-old gentleman who had undergone excision of an ESMC of the thigh in 2009 and presented with sudden onset abdominal pain and icterus in 2019. Radiological imaging revealed calcified mass of the pancreas with multiple nodules with extension into the adipose tissue. Distal pancreatectomy was performed and the pathology revealed a bimorphic tumor composed of undifferentiated round blue cells with abrupt transition to hyaline cartilage, typical of mesenchymal chondrosarcoma. To the best of our knowledge, there are only seven prior cases of metastatic ESMC of the pancreas in the English literature. Surgical intervention appears to be the preferred modality of treatment for metastatic pancreatic tumors. These patients may have long latency period before metastasizing and seem to have a good survival period post excision.


Author(s):  
Debadrita Ray ◽  
Nabhajit Mallik ◽  
Sreejesh Sreedharanunni ◽  
Arihant Jain ◽  
Amanjit Bal ◽  
...  
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document