CHANGES IN PLASMA GROWTH HORMONE LEVELS IN RETARDED CHILDREN

2008 ◽  
Vol 12 (3-4) ◽  
pp. 294-306
Author(s):  
J. HILLMAN ◽  
J. HAMMOND ◽  
J. SOKOLA ◽  
M. REISS
2010 ◽  
Vol 2010 (oct18 2) ◽  
pp. bcr1220092559-bcr1220092559 ◽  
Author(s):  
F. Yokota ◽  
H. Arima ◽  
M. Hirano ◽  
T. Uchikawa ◽  
Y. Inden ◽  
...  

1970 ◽  
Vol 31 (2) ◽  
pp. 358-363 ◽  
Author(s):  
R. W. Purchas ◽  
K. L. Macmillan ◽  
H. D. Hafs

1988 ◽  
Vol 66 (4) ◽  
pp. 853-855 ◽  
Author(s):  
Bruce A. Barrett ◽  
Brian A. McKeown

During the increased locomotor activity of migration many salmonids do not actively feed and it is likely that metabolic alterations occur to facilitate the mobilization of stored reserves. The present laboratory study was designed to simulate the occurrence of exercise and starvation as natural parameters of migration and to assess the effects of such parameters on levels of plasma growth hormone, which might indicate alterations in metabolism during migration. Juvenile steelhead trout, Salmo gairdneri, were starved for a 30-day period. Starved individuals exhibited a marked increase in plasma growth hormone concentration (38.6 ± 6.7 ng/mL) compared with control individuals held on a normal feeding regime (6.4 ± 1.84 ng/mL). A subgroup of fish from the starved group were exercised by being forced to swim at 1.5 body lengths/s for a 24-h period. Exercised individuals exhibited plasma growth hormone levels in excess of 140 ng/mL. There was no significant difference between the plasma growth hormone levels of unexercised starved fish and exercised fed fish.


1976 ◽  
Vol 83 (1) ◽  
pp. 15-25
Author(s):  
M. Vanderschueren-Lodeweyckx ◽  
W. Proesmans ◽  
E. Eggermont ◽  
R. Eeckels

ABSTRACT The effects of the infusion in four different dosages (0.001, 0.005, 0.02 and 0.2 mg/kg/min during 60 min) of cyclic 3′,5′-adenosine monophosphate and of its dibutyryl derivative on plasma growth hormone and on glucose, immunoreactive insulin and cortisol were studied in 38 normal subjects and in 10 patients with idiopathic hypopituitarism. In normal subjects cyclic 3′,5′-adenosine monophosphate provokes an increase in plasma growth hormone levels (only when a dosage of 0.2 mg/kg/min is used) without any changes in plasma glucose, insulin and cortisol. The maximal value of the means is observed 75 min after starting the infusion. Dibutyryl cyclic 3′,5′-adenosine monophosphate (0.2 and 0.02 mg/kg/min) provokes a dose-related rise in plasma growth hormone levels which is always preceded by hyperglycaemia and hyperinsulinaemia. The peak of the mean growth hormone levels occurs at 135 min after initiation of the infusion. In all but one hypopituitary patients the nucleotides do not promote growth hormone secretion. It is concluded that exogenous cyclic 3′,5′-adenosine monophosphate and its dibutyryl derivative may not be considered as analogous and that both compounds may contribute to study growth hormone release in normal subjects and in patients with growth abnormalities.


1969 ◽  
Vol 60 (1) ◽  
pp. 121-129 ◽  
Author(s):  
G. Strauch ◽  
E. Modigliani ◽  
P. Luton ◽  
H. Bricaire

ABSTRACT Plasma growth hormone levels were studied in 15 patients with Cushing's syndrome using several stimuli. All tests except one, were performed before treatment. No change occurred in 6 patients during acute hypoglycaemia and in 11 out of 13 after a glucose load. Arginine given intravenously to 11 subjects elicited a rise in 7 out of 8 females and 1 out of 3 males. From patients who responded to arginine infusion, 6 were insensitive to one or two of the above mentioned stimuli. A selective inhibition of the releasing mechanisms might account for the partial somatotrophin insufficiency found in Cushing's syndrome.


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