Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR)

1990 ◽  
Vol 43 (2) ◽  
pp. 131-138 ◽  
Author(s):  
Peter W. Andrews ◽  
Edward Nudelman ◽  
Sen-Itiroh Hakomori ◽  
Bruce A. Fenderson
Keyword(s):  
Retinoic Acid ◽  
Embryonal Carcinoma ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells ◽  
Hexamethylene Bisacetamide

Dickkopf-3 alters the morphological response to retinoic acid during neuronal differentiation of human embryonal carcinoma cells

2014 ◽  
Vol 74 (12) ◽  
pp. 1243-1254 ◽  
Author(s):  
Rocío Jiménez Alfonso ◽  
Irantzu Gorroño-Etxebarria ◽  
Miriam Rabano ◽  
Maria dM. Vivanco ◽  
Robert Kypta
Keyword(s):  
Retinoic Acid ◽  
Neuronal Differentiation ◽  
Embryonal Carcinoma ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells ◽  
Morphological Response

Midkine Is a Mediator of Retinoic Acid-Induced Neuronal Differentiation of Embryonal Carcinoma Cells

1993 ◽  
Vol 192 (3) ◽  
pp. 1312-1318 ◽  
Author(s):  
M. Michikawa ◽  
R.Y. Xu ◽  
H. Muramatsu ◽  
T. Muramatsu ◽  
S.U. Kim
Keyword(s):  
Retinoic Acid ◽  
Neuronal Differentiation ◽  
Embryonal Carcinoma ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells

scholarly journals The cell cycle, cell death, and cell morphology during retinoic acid-induced differentiation of embryonal carcinoma cells

1984 ◽  
Vol 104 (2) ◽  
pp. 297-307 ◽  
Author(s):  
C.L. Mummery ◽  
C.E. van den Brink ◽  
P.T. van der Saag ◽  
S.W. de Laat
Keyword(s):  
Cell Cycle ◽  
Cell Death ◽  
Retinoic Acid ◽  
Cell Morphology ◽  
Embryonal Carcinoma ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells ◽  
Induced Differentiation

scholarly journals Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

1982 ◽  
Vol 94 (2) ◽  
pp. 253-262 ◽  
Author(s):  
E M Jones-Villeneuve ◽  
M W McBurney ◽  
K A Rogers ◽  
V I Kalnins
Keyword(s):  
Retinoic Acid ◽  
Glial Cells ◽  
Embryonal Carcinoma ◽  
Acetylcholinesterase Activity ◽  
Cell Types ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells ◽  
Neurofilament Protein ◽  
Acid Toxicity ◽  
Precocious Development

Murine embryonal carcinoma cells can differentiate into a varied spectrum of cell types. We observed the abundant and precocious development of neuronlike cells when embryonal carcinoma cells of various pluripotent lines were aggregated and cultured in the presence of nontoxic concentrations of retinoic acid. Neuronlike cells were also formed in retinoic acid-treated cultures of the embryonal carcinoma line, P19, which does not differentiate into neurons in the absence of the drug. The neuronal nature of these cells was confirmed by their staining with antiserum directed against neurofilament protein in indirect immunofluorescence experiments. Retinoic acid-treated cultures also contained elevated acetylcholinesterase activity. Glial cells, identified by immunofluorescence analysis of their intermediate filaments, and a population of fibroblastlike cells were also present in retinoic acid-treated cultures of P19 cells. We did not observe embryonal carcinoma, muscle, or epithelial cells in these cultures. Neurons and glial cells appeared in cultures exposed to retinoic acid for as little as 48 h. We found no evidence for retinoic acid toxicity, suggesting that the effect of the drug was to induce the development of neurons and glia rather than to select against cells differentiating along other developmental pathways.

Activation of four homeobox gene clusters in human embryonal carcinoma cells induced to differentiate by retinoic acid

1988 ◽  
Vol 37 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Fulvio Mavilio ◽  
Antonio Simeone ◽  
Edoardo Boncinelli ◽  
Peter W. Andrews
Keyword(s):  
Retinoic Acid ◽  
Embryonal Carcinoma ◽  
Homeobox Gene ◽  
Gene Clusters ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells

Regulation of neurogenesis and gliogenesis of retinoic acid‐induced P19 embryonal carcinoma cells by P2X2 and P2X7 receptors studied by RNA interference

2012 ◽  
Vol 30 (2) ◽  
pp. 91-97 ◽  
Author(s):  
Katia K. Yuahasi ◽  
Marcos A. Demasi ◽  
Alessandra S.K. Tamajusuku ◽  
Guido Lenz ◽  
Mari C. Sogayar ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Rna Interference ◽  
Embryonal Carcinoma ◽  
Carcinoma Cells ◽  
Embryonal Carcinoma Cells ◽  
P2x7 Receptors ◽  
P19 Embryonal Carcinoma Cells

Fibroblast feeder layers inhibit differentiation of retinoic acid-treated embryonal carcinoma cells by increasing the probability of stem cell renewal

1984 ◽  
Vol 152 (2) ◽  
pp. 378-389 ◽  
Author(s):  
Maurice J. Rosenstraus ◽  
Barbara Sterman ◽  
Amanda Carr ◽  
Lori Brand
Keyword(s):  
Stem Cell ◽  
Retinoic Acid ◽  
Embryonal Carcinoma ◽  
Carcinoma Cells ◽  
Cell Renewal ◽  
Embryonal Carcinoma Cells ◽  
Stem Cell Renewal ◽  
Feeder Layers
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