Heterogenous Macromolecular Contributions to Early Mouse Embryo Development. (in vitro culture/mouse embryos/abnormal development/growth factors/inductors)

1990 ◽  
Vol 32 (2) ◽  
pp. 131-137 ◽  
Author(s):  
Yu-Chin Hsu
Keyword(s):  
Growth Factors ◽  
In Vitro Culture ◽  
Mouse Embryo ◽  
Mouse Embryos ◽  
Abnormal Development ◽  
Early Mouse Embryo ◽  
Mouse Embryo Development ◽  
Development In Vitro ◽  
Early Mouse

In vitro effects of phthalic acid mono-n-butyl ester and di-n-butyl ester on early mouse embryo development

2007 ◽  
Vol 88 ◽  
pp. S307
Author(s):  
N.D. Tran ◽  
G. Giritharan ◽  
V. Fujimoto ◽  
P.C. Klatsky ◽  
T. Woodruff ◽  
...  
Keyword(s):  
Embryo Development ◽  
Mouse Embryo ◽  
Phthalic Acid ◽  
Butyl Ester ◽  
Early Mouse Embryo ◽  
Mouse Embryo Development ◽  
In Vitro Effects ◽  
Early Mouse

Early mouse preimplantation development is unaffected by microinjection of metallothionein antibodies

Zygote ◽  
1995 ◽  
Vol 3 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Elena Ibánez ◽  
Francesca Vidal ◽  
Juan Hidalgo
Keyword(s):  
Embryo Development ◽  
Mouse Embryo ◽  
Normal Mouse ◽  
Polyclonal Antibodies ◽  
Experimental Treatment ◽  
Mouse Embryos ◽  
Mouse Embryo Development ◽  
Morula Stage ◽  
Early Mouse

SummaryPolyclonal antibodies that cross-react with rodent metallothionein I (MT I) and metallothionein II (MT II) were microinjected in 1-cell and 2-cell mouse embryos, into either the cytoplasm or the nucleus. Regardless of the experimental treatment, mouse embryo development in vitro was not affected and most of the embryos cleaved normally until the morula stage. The results suggest that metallothionein is not essential for normal mouse early preimplantational development, in agreement with recent studies in mice with inactivated MT I and MT II genes.

Comparative effects of essential and nonessential metals on preimplantation mouse embryo development in vitro

Toxicology ◽  
1997 ◽  
Vol 116 (1-3) ◽  
pp. 123-131 ◽  
Author(s):  
Lynn A. Hanna ◽  
Jeffrey M. Peters ◽  
Lynn M. Wiley ◽  
Michael S. Clegg ◽  
Carl L. Keen
Keyword(s):  
Embryo Development ◽  
Mouse Embryo ◽  
Mouse Embryo Development ◽  
Preimplantation Mouse Embryo ◽  
Preimplantation Mouse ◽  
Development In Vitro

A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo

Development ◽  
2002 ◽  
Vol 129 (20) ◽  
pp. 4807-4819 ◽  
Author(s):  
Makoto Ishibashi ◽  
Andrew P. McMahon
Keyword(s):  
Spinal Cord ◽  
Sonic Hedgehog ◽  
Mouse Embryo ◽  
Mouse Embryos ◽  
Cell Populations ◽  
Subsequent Growth ◽  
Early Mouse Embryo ◽  
Present Evidence ◽  
Spinal Cord Dorsal ◽  
Early Mouse

Sonic hedgehog (Shh) is a key signal in the specification of ventral cell identities along the length of the developing vertebrate neural tube. In the presumptive hindbrain and spinal cord, dorsal development is largely Shh independent. By contrast, we show that Shh is required for cyclin D1 expression and the subsequent growth of both ventral and dorsal regions of the diencephalon and midbrain in early somite-stage mouse embryos. We propose that a Shh-dependent signaling relay regulates proliferation and survival of dorsal cell populations in the diencephalon and midbrain. We present evidence that Fgf15 shows Shh-dependent expression in the diencephalon and may participate in this interaction, at least in part, by regulating the ability of dorsal neural precursors to respond to dorsally secreted Wnt mitogens.

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