Association of a single nucleotide polymorphism in the steroid and xenobiotic receptor (SXR) gene (IVS1-579A/G) with bone mineral density

2007 ◽  
Vol 7 (2) ◽  
pp. 104-109 ◽  
Author(s):  
Tomohiko Urano ◽  
Masataka Shiraki ◽  
Yasuyoshi Ouchi ◽  
Satoshi Inoue
2007 ◽  
Vol 7 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Takahiko Usui ◽  
Tomohiko Urano ◽  
Masataka Shiraki ◽  
Yasuyoshi Ouchi ◽  
Satoshi Inoue

2020 ◽  
Author(s):  
Lizhi Zhang ◽  
Jinwei He ◽  
Xiang Sun ◽  
Dongyue Pang ◽  
Jingjing Hu ◽  
...  

Abstract Background: GIP (glucose-dependent insulinotropic peptide) has been found to affect bone metabolism. GIPR single nucleotide polymorphism (SNP) is related to its activity, but the relationship between GIPR SNP and osteoporosis in postmenopausal women is still unclear. The Aim of this study was to investigate the association between GIPR SNP and bone mineral density (BMD) in postmenopausal women in Shanghai.Methods: GIP SNP rs10423928 was detected in 884 postmenopausal women in Shanghai. The correlation between GIPR SNP and BMD was further assessed.Results: There was a statistical difference between the dominant model of this site rs10423928 and the bone mineral density of the femoral neck (P = 0.035) and the Wards triangle area (P = 0.033). Conclusions: The rs10423928 of GIPR is related to the BMD of postmenopausal women in Shanghai, China.


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