Group A streptococcal toxic shock syndrome with extremely aggressive course in the third trimester

2010 ◽  
Vol 36 (4) ◽  
pp. 852-855 ◽  
Author(s):  
Takashi Sugiyama ◽  
Takumi Kobayashi ◽  
Kenji Nagao ◽  
Tsuyoshi Hatada ◽  
Hideo Wada ◽  
...  
2021 ◽  
Author(s):  
Yasha Luo ◽  
Minling Zheng ◽  
Yanyuan Chen ◽  
Chunming Gu ◽  
Lijuan Lv ◽  
...  

Abstract Background Group A streptococcal (GAS) toxic shock syndrome (TSS) is a rare invasive disease, causing a high risk of maternal and fetal mortality during pregnancy. We report a fatal case of a female caused by GAS-TSS in the third trimester of pregnancy in Guangzhou, China. Case presentation: The patient is a 33-year-old female who presented at 37 weeks’ gestation with a history of three hours fever. She underwent an emergency cesarean section due to fetal bradycardia. The neonate survived after an aggressive anti-infection treatment. However, the patient’s condition deteriorated rapidly after the operation and the patient died of disseminated intravascular coagulation and septic shock within 24h after admission. She was finally diagnosed with GAS-TSS. The GAS strains were isolated from two bottles of blood cultures, which confirmed as Streptococcus pyogenes by 16S gene sequencing and identified as serotype M1 by molecular typing. Conclusions Dramatical clinical picture and laboratory characters of the pregnant woman presented here might help improve clinicians' awareness and recognition of Streptococcus pyogenes, which could be of great importance for the early diagnosis of GAS- TSS in pregnancy.


2021 ◽  
Author(s):  
Yasha Luo ◽  
Minling Zheng ◽  
Yanyuan Chen ◽  
Chunming Gu ◽  
Lijuan Lv ◽  
...  

Abstract Background: Group A streptococcal (GAS) toxic shock syndrome (TSS) is a rare invasive disease, causing a high risk of maternal and fetal mortality during pregnancy. We report a fatal case of a female caused by GAS-TSS in the third trimester of pregnancy in Guangzhou, China. Case presentation: The patient is a 33-year-old female who presented at 37 weeks’ gestation with a history of three hours fever. The patient underwent an early onset and rapid progression with dramatic clinical picture and laboratory characters within 24 hours. The neonate survived after an aggressive anti-infection treatment.The GAS strains were isolated from two bottles of blood cultures and airway secretion culture, which confirmed as Streptococcus pyogenes associated with genotype emm1 by molecular analysis.Conclusion: Dramatic clinical picture and laboratory characters of the pregnant woman presented here might help improve clinicians' awareness and recognition of Streptococcus pyogenes, which could be of great importance for the early diagnosis of GAS- TSS in pregnancy.


2017 ◽  
Vol 43 (10) ◽  
pp. 1639-1643
Author(s):  
Mohamad Irani ◽  
Rodney McLaren ◽  
Richard H. Savel ◽  
Oksana Bogatyryova ◽  
Fady Khoury-Collado

2013 ◽  
Vol 95 (7) ◽  
pp. 457-460 ◽  
Author(s):  
J AZ Hung ◽  
P Rajeev

Group A streptococcal toxic shock syndrome following clean surgery is a rare occurrence. Its incidence following thyroid surgery has not been described in the literature. We report on the presentation and management of severe streptococcal toxic shock syndrome following a total thyroidectomy for a multinodular goitre in a patient with Cowden syndrome. This report presents an overview of streptococcal toxic shock syndrome with a focus on the management issues to consider so as to improve patient outcome. All surgeons must maintain a high index of suspicion for this rare but dangerous entity.


2014 ◽  
Vol 291 (1) ◽  
pp. 5-7 ◽  
Author(s):  
Junichi Hasegawa ◽  
Akihiko Sekizawa ◽  
Jun Yoshimatsu ◽  
Takeshi Murakoshi ◽  
Kazuhiro Osato ◽  
...  

2019 ◽  
Vol 160 (48) ◽  
pp. 1887-1893
Author(s):  
Bálint Gergely Szabó ◽  
Rebeka Kiss ◽  
Katalin Szidónia Lénárt ◽  
Nikolova Radka ◽  
Béla Kádár

Abstract: Streptococcal toxic shock syndrome (STSS) is a hyperacute, life-threatening illness, a complication of invasive streptococcal (mostly group A, rarely groups B, G or C) infection. There is no portal of entry (skin, vagina, pharynx) in nearly half of the STSS cases. The initial signs and symptoms (fever, flu-like complaints, hypotension) are scarce and aspecific, but because of its rapid progression and poor prognosis, early high level of suspicion is necessary. Management has 3 crucial points: initiation of anti-streptococcal regimen (and intravenous immunoglobulin in some cases), aggressive intensive care support of multi-organ failure, and surgical control of the infective source. In this article, we present a case of a patient succumbing to streptococcal toxic shock syndrome which was preceded by primary S. pyogenes bacteremia, and review the key points of this potentially fatal disease for practising clinicians. Orv Hetil. 2019; 160(48): 1887–1893.


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