Anti-CD3 monoclonal antibody treatment in newly diagnosed Type 1 diabetes patients: a hypothetical modelling analysis

2010 ◽  
Vol 27 (2) ◽  
pp. 189-196 ◽  
Author(s):  
J. Smith-Palmer ◽  
B. H. Curtis ◽  
K. S. Boye ◽  
G. Goodall ◽  
S. R. Pillemer
Keyword(s):  
Monoclonal Antibody ◽  
Type 1 Diabetes ◽  
Newly Diagnosed ◽  
Antibody Treatment ◽  
Modelling Analysis ◽  
Monoclonal Antibody Treatment ◽  
Diabetes Patients

scholarly journals Increased DKA at presentation among newly diagnosed type 1 diabetes patients with or without COVID ‐19: Data from a multi‐site surveillance registry

2020 ◽  
Author(s):  
Kara Beliard ◽  
Osagie Ebekozien ◽  
Carla Demeterco‐Berggren ◽  
Guy Todd Alonso ◽  
Mary Pat Gallagher ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Newly Diagnosed ◽  
Diabetes Patients

scholarly journals A study of 51 subtypes of peripheral blood immune cells in newly diagnosed young type 1 diabetes patients

2019 ◽  
Vol 198 (1) ◽  
pp. 57-70 ◽  
Author(s):  
A. Oras ◽  
A. Peet ◽  
T. Giese ◽  
V. Tillmann ◽  
R. Uibo
Keyword(s):  
Type 1 Diabetes ◽  
Immune Cells ◽  
Peripheral Blood ◽  
Newly Diagnosed ◽  
Diabetes Patients

Newly diagnosed type 1 diabetes patients exhibit lower hepatic ATP concentrations despite normal hepatocellular lipid accumulation

2015 ◽  
Vol 10 (S 01) ◽  
Author(s):  
S Gancheva ◽  
A Bierwagen ◽  
P Begovatz ◽  
J Lundbom ◽  
P Nowotny ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Lipid Accumulation ◽  
Newly Diagnosed ◽  
Diabetes Patients

Neutralizing Ljungan virus antibodies in children with newly diagnosed type 1 diabetes

2021 ◽  
Vol 102 (5) ◽  
Author(s):  
Annika Lundstig ◽  
Sharia L. McDonald ◽  
Marlena Maziarz ◽  
William C. Weldon ◽  
Fariba Vaziri-Sani ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Bank Vole ◽  
Acid Decarboxylase ◽  
Newly Diagnosed ◽  
Future Studies ◽  
Ljungan Virus ◽  
Islet Antigen ◽  
Diabetes Patients

Ljungan virus (LV), a Parechovirus of the Picornavirus family, first isolated from a bank vole at the Ljungan river in Sweden, has been implicated in the risk for autoimmune type 1 diabetes. An assay for neutralizing Ljungan virus antibodies (NLVA) was developed using the original 87–012 LV isolate. The goal was to determine NLVA titres in incident 0–18 years old newly diagnosed type 1 diabetes patients (n=67) and school children controls (n=292) from Jämtland county in Sweden. NLVA were found in 41 of 67 (61 %) patients compared to 127 of 292 (44 %) controls (P=0.009). In the type 1 diabetes patients, NLVA titres were associated with autoantibodies to glutamic acid decarboxylase (GADA) (P=0.023), but not to autoantibodies against insulin (IAA) or islet antigen-2 (IA-2A). The NLVA assay should prove useful for further investigations to determine levels of LV antibodies in patients and future studies to determine a possible role of LV in autoimmune type 1 diabetes.

scholarly journals CTSH regulates  -cell function and disease progression in newly diagnosed type 1 diabetes patients

2014 ◽  
Vol 111 (28) ◽  
pp. 10305-10310 ◽  
Author(s):  
T. Floyel ◽  
C. Brorsson ◽  
L. B. Nielsen ◽  
M. Miani ◽  
C. H. Bang-Berthelsen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Disease Progression ◽  
Cell Function ◽  
Newly Diagnosed ◽  
Diabetes Patients
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