scholarly journals Activity of medicinal plant extracts against hospital isolates of methicillin-resistant Staphylococcus aureus

2005 ◽  
Vol 11 (6) ◽  
pp. 510-512 ◽  
Author(s):  
S.P. Voravuthikunchai ◽  
L. Kitpipit
Keyword(s):  
Staphylococcus Aureus ◽  
Medicinal Plant ◽  
Plant Extracts ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Medicinal Plant Extracts

scholarly journals A review on medicinal plant extracts and their active ingredients against methicillin-resistant and methicillin-sensitive Staphylococcus aureus

2019 ◽  
Vol 8 (3) ◽  
pp. 173-184
Author(s):  
Marzieh Askarinia ◽  
Ali Ganji ◽  
Farhad Jadidi-Niaragh ◽  
Sajad Hasanzadeh ◽  
Bahram Mohammadi ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Human Beings ◽  
Active Ingredients ◽  
Methicillin Resistant ◽  
Medicinal Plant Extracts ◽  
Lactam Antibiotic ◽  
New Strategies

Staphylococcus aureus is among the pathogens capable of developing a broad spectrum of infections in human beings. In addition to the hospital, the bacterium is present in the community and has a high resistance to antibiotics, which is also increasing on an ongoing basis. Resistance to β-lactam antibiotic family is one of the concerns about the bacterium that has encountered the treatment of such infections with difficulty. Due to the increased resistance and importance of this bacterium, new strategies are needed to control this pathogen. One of these approaches is the use of medicinal plants, which has attracted many researchers in the last decade. Several studies have been carried out or are being designed using various herbs to find active ingredients to deal with this bacterium. The aim of this study was to present the antibacterial activity of different medicinal plants and the effects of their active ingredients on methicillin-resistant and methicillin-sensitive S. aureus and to clarify the pathway to further studies in this regard.

scholarly journals Biofilm Inhibition and Eradication Properties of Medicinal Plant Essential Oils against Methicillin-Resistant Staphylococcus aureus Clinical Isolates

2020 ◽  
Vol 13 (11) ◽  
pp. 369
Author(s):  
Fethi Ben Abdallah ◽  
Rihab Lagha ◽  
Ahmed Gaber
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plant ◽  
Essential Oils ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Isolates ◽  
Mass Spectrometry Analysis ◽  
Biofilm Inhibition ◽  
Methicillin Resistant ◽  
Plant Essential Oils

Methicillin-resistant Staphylococcus aureus is a major human pathogen that poses a high risk to patients due to the development of biofilm. Biofilms, are complex biological systems difficult to treat by conventional antibiotic therapy, which contributes to >80% of humans infections. In this report, we examined the antibacterial activity of Origanum majorana, Rosmarinus officinalis, and Thymus zygis medicinal plant essential oils against MRSA clinical isolates using disc diffusion and MIC methods. Moreover, biofilm inhibition and eradication activities of oils were evaluated by crystal violet. Gas chromatography–mass spectrometry analysis revealed variations between oils in terms of component numbers in addition to their percentages. Antibacterial activity testing showed a strong effect of these oils against MRSA isolates, and T. zygis had the highest activity succeeded by O. majorana and R. officinalis. Investigated oils demonstrated high biofilm inhibition and eradication actions, with the percentage of inhibition ranging from 10.20 to 95.91%, and the percentage of eradication ranging from 12.65 to 98.01%. O. majorana oil had the highest biofilm inhibition and eradication activities. Accordingly, oils revealed powerful antibacterial and antibiofilm activities against MRSA isolates and could be a good alternative for antibiotics substitution.

scholarly journals Actividad antibacteriana de extractos de plantas provenientes del área rural de Soracá contra Staphylococcus aureus resistente a meticilina (SARM)/Antibacterial activity of plant extracts from rural area of Soracá against methicillin-resistant staphylococcus Aureus (MRSA)

2015 ◽  
Vol 7 (1) ◽  
pp. 4
Author(s):  
Román Yesid Ramírez ◽  
Diana Natalia Mojica Ávila ◽  
Mery Isabel Espitia
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Rural Area ◽  
Plant Extracts ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Para Determinar

Introducción: Staphylococcus aureus resistente a la meticilina (SARM) es una cepa bacteriana resistente a una gran variedad de antibióticos, incluidos los carbapenems y la vancomicina. Actualmente se cuenta con muy pocas opciones terapéuticas para el tratamiento de  la infección por SARM, por lo tanto el enfoque hacia las plantas como fuente de moléculas con acción antibacteriana es una buena opción para investigar posibles  compuestos activos. Objetivo: Evaluar la actividad antibacteriana de extractos metanólicos y diclorometánicos de plantas (reportadas por la población rural de Soracá-Colombia como tratamiento empírico para las infecciones) contra SARM. Métodos: Estudio experimental en el cual se aplicaron 16 tratamientos (extractos) a una cepa de SARM. Los extractos provinieron de siete plantas y se obtuvieron por medio de extracción continua con solventes (metanol y diclorometano) usando Soxhlet. El método de microdilución en caldo fue usado para determinar la concentración mínima inhibitoria (CMI) de los extractos, realizando inicialmente un tamizaje a una concentración de 10 mg/mL y luego hallando la CMI de los extractos que tuvieron actividad a tal concentración. La inhibición se  verificó por lectura visual después de aplicar 3-(4,5-dimetiltiazol-2-il)-2,5-difeniltetrazolio (MTT). Resultados: De los 16 extractos probados, seis inhibieron al SARM en concentración de 10 mg/mL. Tales extractos tuvieron efecto a una CMI de 1,25 mg/mL. Conclusión: Los seis extractos de las plantas que tuvieron acción inhibitoria frente a SARM son fuentes potenciales de moléculas que deben ser estudiadas más a fondo con el fin de aportar al estudio de posibles alternativas contra la resistencia bacteriana.

scholarly journals Antibacterial effects of 4 methanol plant extracts (Lamiaceae) against 10 Methicillin Resistant Staphylococcus aureus isolates

2015 ◽  
Vol 9 (2) ◽  
pp. 51-54
Author(s):  
Maryam Paydar ◽  
Ashraf Kariminik
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Plant Extracts ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Zataria Multiflora ◽  
Methicillin Resistant ◽  
Herbal Therapies

Antibiotic resistance has paved the way for replacing conventional medications with herbal therapies that supposedly have less side-effect. This research is an experimental study and a fundamental- functional one. The present study aimed to investigate the antibacterial effect of 4 plant extracts from Lamiaceae on 10 methicillin resistant Staphylococcus aureus isolates. Methanol extracts were prepared by maceration method for 10 days in room temperature and then filtered with wathman paper No.1 and concentrated by rotary evaporator system. Different concentration of each extract were prepared in dimethyl sulfoxide: methanol (1:1 v/v) and bioassayed on 10 MRSA isolates by agar well diffusion method in Muller-Hinton agar medium. Plates were incubated in 37°C for 24 hours. After incubation period, zone of inhibition was measured in millimeter and the antibacterial effect of extracts were evaluated. According to antibiogram test, some of Staphylococcus aureus isolates were sensitive to the used extracts with different MIC.MIC values about all Staphylococcus aureus isolates about Zataria multiflora, Mentha longifolia, Ziziphor clinopodioide and Satureja hortensis were 15, 30, 30 and 15 mg/ml respectively. Because of regarding the fact that antibiotic resistance is growing, according to the acquired results we expect to be able to use plant extracts against Staphylococcus aureus resistant to meticillin in controling the infections or as preservatives in food sciences and in the next step separating of effective substances were suggested.DOI: http://dx.doi.org/10.3126/ijls.v9i2.12045 International Journal of Life Sciences 9 (2) : 2015; 51-54

scholarly journals Synergistic Effects of Artemisia vulgaris, Ocimum tenuiflorum, Azadirachta indica and Castanopsis indica Extracts against Methicillin-Resistant Staphylococcus aureus

2017 ◽  
Vol 5 (1) ◽  
pp. 38-44
Author(s):  
Jyoti Chhetri ◽  
Krishna Gurung ◽  
Abhisek Khadka ◽  
Reeju Sharma ◽  
Mira Kumari Khatri ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plant ◽  
Plant Extract ◽  
Antibacterial Agents ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Synergistic Effects ◽  
Health Concern ◽  
Assay Method ◽  
Methicillin Resistant

Staphylococcus aureus is a major public health concern. Methicillin resistant Staphylococcus aureus is not only resistant to methicillin and other β-lactam antibacterial agents but also to other antibacterial agents. Therefore, new agents are needed to treat Methicillin Resistant Staphylococcus aureus (MRSA). The main aim of the present research was to study the antibacterial activity of four plants extract against clinical isolates of Staphylococcus aureus at the purpose of overcoming its infection. The current investigation was carried out at Pokhara Bigyan tatha Prabidhi Campus based on the evaluation of traditional plants on its antibacterial activity against MRSA. Antibacterial activity of the medicinal plant extract was observed by mixing 100 g powder of collected leaves in 70% methanol making 1000 sml. After performed processes, extract was filtered and methanol was evaporated. Antibacterial activity of the medicinal plant extract was determined using agar well diffusion assay method. Methanol leaf extracts may have the potential to act against MRSA and could be a possible source to obtain new and effective herbal medicines to treat infections caused by methicillin resistant strains of microorganisms from community as well as hospital settings. The synergistic effect was clearly observed among all four medicinal herbs.

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