scholarly journals A review on medicinal plant extracts and their active ingredients against methicillin-resistant and methicillin-sensitive Staphylococcus aureus

2019 ◽  
Vol 8 (3) ◽  
pp. 173-184
Author(s):  
Marzieh Askarinia ◽  
Ali Ganji ◽  
Farhad Jadidi-Niaragh ◽  
Sajad Hasanzadeh ◽  
Bahram Mohammadi ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Human Beings ◽  
Active Ingredients ◽  
Methicillin Resistant ◽  
Medicinal Plant Extracts ◽  
Lactam Antibiotic ◽  
New Strategies

Staphylococcus aureus is among the pathogens capable of developing a broad spectrum of infections in human beings. In addition to the hospital, the bacterium is present in the community and has a high resistance to antibiotics, which is also increasing on an ongoing basis. Resistance to β-lactam antibiotic family is one of the concerns about the bacterium that has encountered the treatment of such infections with difficulty. Due to the increased resistance and importance of this bacterium, new strategies are needed to control this pathogen. One of these approaches is the use of medicinal plants, which has attracted many researchers in the last decade. Several studies have been carried out or are being designed using various herbs to find active ingredients to deal with this bacterium. The aim of this study was to present the antibacterial activity of different medicinal plants and the effects of their active ingredients on methicillin-resistant and methicillin-sensitive S. aureus and to clarify the pathway to further studies in this regard.

Antibacterial Activity of Thai Medicinal Plants against Methicillin-resistant Staphylococcus aureus

Fitoterapia ◽  
2009 ◽  
Vol 80 (2) ◽  
pp. 102-104 ◽  
Author(s):  
Mullika Traidej Chomnawang ◽  
Suvimol Surassmo ◽  
Karn Wongsariya ◽  
Nuntavan Bunyapraphatsara
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Thai Medicinal Plants

scholarly journals Biofilm Inhibition and Eradication Properties of Medicinal Plant Essential Oils against Methicillin-Resistant Staphylococcus aureus Clinical Isolates

2020 ◽  
Vol 13 (11) ◽  
pp. 369
Author(s):  
Fethi Ben Abdallah ◽  
Rihab Lagha ◽  
Ahmed Gaber
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plant ◽  
Essential Oils ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Isolates ◽  
Mass Spectrometry Analysis ◽  
Biofilm Inhibition ◽  
Methicillin Resistant ◽  
Plant Essential Oils

Methicillin-resistant Staphylococcus aureus is a major human pathogen that poses a high risk to patients due to the development of biofilm. Biofilms, are complex biological systems difficult to treat by conventional antibiotic therapy, which contributes to >80% of humans infections. In this report, we examined the antibacterial activity of Origanum majorana, Rosmarinus officinalis, and Thymus zygis medicinal plant essential oils against MRSA clinical isolates using disc diffusion and MIC methods. Moreover, biofilm inhibition and eradication activities of oils were evaluated by crystal violet. Gas chromatography–mass spectrometry analysis revealed variations between oils in terms of component numbers in addition to their percentages. Antibacterial activity testing showed a strong effect of these oils against MRSA isolates, and T. zygis had the highest activity succeeded by O. majorana and R. officinalis. Investigated oils demonstrated high biofilm inhibition and eradication actions, with the percentage of inhibition ranging from 10.20 to 95.91%, and the percentage of eradication ranging from 12.65 to 98.01%. O. majorana oil had the highest biofilm inhibition and eradication activities. Accordingly, oils revealed powerful antibacterial and antibiofilm activities against MRSA isolates and could be a good alternative for antibiotics substitution.

scholarly journals Antibacterial activity of endophytic fungi in Pometia pinnata against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus

2020 ◽  
Vol 21 (11) ◽  
Author(s):  
Ratna Setyaningsih ◽  
Ari Susilowati ◽  
Dina Prasetyani
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Endophytic Fungi ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Its Region ◽  
Inhibition Zone ◽  
Antibacterial Activities ◽  
Bacterial Cells ◽  
Methicillin Resistant

Abstract. Endophytic fungi associated with medicinal plants are able to produce bioactive compounds which potentially contain medicinal ingredients. Matoa (Pometia pinnata J. R. Forst & G. Forst) is one of Indonesian medicinal plants. This research aims to test antibacterial activities of ethyl acetate extract of matoa’s endophytic fungi to Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA) and also identify isolates having high antibacterial activity. Initial test on antibacterial activity was conducted by using paper disc diffusion, while advanced test was conducted by determining minimum inhibitory concentration (MIC). The fungi were identified in morphological and molecular manner with amplification and sequencing of ITS region. Bacterial cells exposed to the extract were observed by using scanning electron microscope (SEM). Isolate AM72 was found out to have the highest antibacterial activity compared to other 12 isolates tested, with inhibition zone diameter of 31.57 mm to S. aureus and 22.87 mm to MRSA. Isolate AM72 was identified as Lasiodiplodia theobromae. Isolate BMB identified as Aspergillus oryzae produced inhibition zone with 21.96 mm diameter to S. aureus and 21.50 mm diameter to MRSA. Advanced test to isolate AM72 gave the same MIC results to S. aureus and MRSA of 1.56%. Antibacterial compound produced by isolate AM72 were found out to be able to damage bacterial cell walls. Keywords: Antibacterial, Endohpytic Fungi, Matoa, S. aureus, MRSA  

scholarly journals Synergistic Effects of Artemisia vulgaris, Ocimum tenuiflorum, Azadirachta indica and Castanopsis indica Extracts against Methicillin-Resistant Staphylococcus aureus

2017 ◽  
Vol 5 (1) ◽  
pp. 38-44
Author(s):  
Jyoti Chhetri ◽  
Krishna Gurung ◽  
Abhisek Khadka ◽  
Reeju Sharma ◽  
Mira Kumari Khatri ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Medicinal Plant ◽  
Plant Extract ◽  
Antibacterial Agents ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Synergistic Effects ◽  
Health Concern ◽  
Assay Method ◽  
Methicillin Resistant

Staphylococcus aureus is a major public health concern. Methicillin resistant Staphylococcus aureus is not only resistant to methicillin and other β-lactam antibacterial agents but also to other antibacterial agents. Therefore, new agents are needed to treat Methicillin Resistant Staphylococcus aureus (MRSA). The main aim of the present research was to study the antibacterial activity of four plants extract against clinical isolates of Staphylococcus aureus at the purpose of overcoming its infection. The current investigation was carried out at Pokhara Bigyan tatha Prabidhi Campus based on the evaluation of traditional plants on its antibacterial activity against MRSA. Antibacterial activity of the medicinal plant extract was observed by mixing 100 g powder of collected leaves in 70% methanol making 1000 sml. After performed processes, extract was filtered and methanol was evaporated. Antibacterial activity of the medicinal plant extract was determined using agar well diffusion assay method. Methanol leaf extracts may have the potential to act against MRSA and could be a possible source to obtain new and effective herbal medicines to treat infections caused by methicillin resistant strains of microorganisms from community as well as hospital settings. The synergistic effect was clearly observed among all four medicinal herbs.

scholarly journals Ethnopharmacological survey and antibacterial activity of medicinal plant extracts used against bacterial enteritis in rabbits

2021 ◽  
Author(s):  
Mireille Tuedom Chouegouong ◽  
Michele Stella Majoumouo ◽  
Elisabeth Zeuko’o Menkem ◽  
Lorette Victorine Yimgang ◽  
Rufin Marie Kouipou Toghueo ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Psidium Guajava ◽  
Synergistic Interaction ◽  
Tithonia Diversifolia ◽  
Bidens Pilosa ◽  
Plant Parts ◽  
Medicinal Plant Extracts ◽  
Causative Agents

AbstractBacterial enteritis is one of the diseases negatively affecting the rabbit farming industry. Communities across the globe are using medicinal plants as an alternative treatment against many diseases in rabbits. This study aimed at identifying medicinal plants used by local farmers in Cameroon and evaluate their antibacterial activity alone and in combination with oxytetracycline against some bacterial causative agents of diarrhoea in rabbits. The ethnopharmacological survey was performed in Cameroon’s Western and Central regions, where breeders were interviewed about their knowledge on the medicinal plants and plant parts often used to cure rabbit diseases, the methods of preparation and the route of administration. Plants were collected, and extracts were prepared by decoction, infusion and maceration using distilled water. The antibacterial activity of extracts and combinations was evaluated against enteropathogenic Escherichia coli, Salmonella enterica and Clostridium perfringens (WAL-14572 HM-310) using the microdilution and checkerboard methods. From the survey, fifteen medicinal plants belonging to nine families, with Asteraceae being the most represented, were identified as currently used to treat diarrhoea in rabbits. Bidens pilosa and Psidium guajava were the most mentioned medicinal plant species with 24 and 17 citations, respectively. Leaves were the most commonly used plant parts, and maceration in water was the primary preparation method of remedies administered orally. Out of the forty-five extracts prepared, only six from Tithonia diversifolia (TdlM, TdlI, TdlD) and Psidium guajava (PglM, PglI, PglD) exhibited potency with MIC values ranging from 1.25 to 5 mg/mL. The combination of infusion extract from leaves of Tithonia diversifolia (TdlI) and decoction extract from Psidium guajava (PglD) exhibited synergistic interaction (FICI = 0.312; 0.281; 0.265), while oxytetracycline in combination with decoction extract from leaves of Psidium guajava (PglD) exhibited a synergistic interaction (FICI = 0.5). The phytochemical screening of the six extracts revealed polyphenols, glycosides, saponins, terpenoids, anthraquinones, tannins and flavonoids. The antibacterial activity of extracts from medicinal plants P. guajava and T. diversifolia demonstrated in the present study supports the use of these plants by farmers of the targeted localities to treat diarrhoea in rabbits.

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