scholarly journals A longitudinal study of the relationship between maternal cardiac output measured by impedance cardiography and uterine artery blood flow in the second half of pregnancy

2010 ◽  
Vol 117 (7) ◽  
pp. 837-844 ◽  
Author(s):  
K Flo ◽  
T Wilsgaard ◽  
Å Vårtun ◽  
G Acharya
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Longitudinal Study ◽  
Uterine Artery ◽  
Impedance Cardiography ◽  
Artery Blood Flow ◽  
The Relationship

scholarly journals An Exploratory Study on the Relationship between Brachial Arterial Blood Flow and Cardiac Output

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Sixiang Jia ◽  
Yiteng Wu ◽  
Wei Wang ◽  
Wenting Lin ◽  
Yiwen Chen ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Brachial Artery ◽  
Theoretical Basis ◽  
Arterial Blood Flow ◽  
Artery Blood Flow ◽  
Korotkoff Sound ◽  
Arterial Blood ◽  
The Mean ◽  
The Relationship

Background. We have obtained prospective clinical outcomes using the brachial artery largely, such as Korotkoff sound and vasomotor function measurement by ultrasound guidance to predict the prognosis of cardiovascular diseases. Very few reports on the quantitative measurement of the relationship between the brachial artery blood flow and cardiac output have been reported. Purpose. (1) To investigate whether the quantitative relationship between the brachial artery blood flow and cardiac output existed. (2) To provide a theoretical basis for taking advantage of artificial intelligence (AI) using Korotkoff sound analogously as far as possible to predict the cardiac output. Methods. A total of 586 patients who underwent cardiac color ultrasound in our center from 2021.3 to 2021.7 were included for analyses. The vascular parameters of the right upper limb brachial artery (such as the Diameter, Area, Blood Velocity, and Flow) were measured immediately after the cardiac color ultrasound, and some basic clinical parameters (Age, Sex, BMI, and Disease) were recorded subsequently. Ultimately, the Mann–Whitney and independent sample T-test were used to analyze the data. Results. (1) The mean Rate of the brachial arterial blood flow to cardiac output was 1.23%, and the mean 95% CI was (1.18%, 1.29%), indicating that the value was mainly concentrated in the current value interval. The indicator demonstrates that there is no significant difference currently among the patients with hypertension, coronary heart disease, and cardiac dysfunction. (2) The brachial artery wall diameter (Dist) is significantly thicker in patients with coronary heart disease and hypertension compared to patients with other cardiovascular diseases. (3) Cardiac output augments remarkably in patients with hypertension. Conclusion. Our study suggests that the Rate (brachial artery blood flow/cardiac output) is a constant of 1.23% approximately. It provides a theoretical basis for the subsequent application of the artificial intelligence (AI) method to predict heart function using Korotkoff sound, cope with large computational amounts, and improve computational speed. It is also indirectly proved that hypertension can lead to a change in peripheral vascular hyperplasia and increase cardiac output.

scholarly journals Preeclampsia: The Relationship between Uterine Artery Blood Flow and Trophoblast Function

2019 ◽  
Vol 20 (13) ◽  
pp. 3263 ◽  
Author(s):  
Anna Ridder ◽  
Veronica Giorgione ◽  
Asma Khalil ◽  
Basky Thilaganathan
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Late Pregnancy ◽  
Trophoblast Invasion ◽  
Artery Blood Flow ◽  
Intrauterine Environment ◽  
Placental Perfusion ◽  
Placental Function ◽  
The Relationship ◽  
Artery Perfusion

Maternal uterine artery blood flow is critical to maintaining the intrauterine environment, permitting normal placental function, and supporting fetal growth. It has long been believed that inadequate transformation of the maternal uterine vasculature is a consequence of primary defective trophoblast invasion and leads to the development of preeclampsia. That early pregnancy maternal uterine artery perfusion is strongly associated with placental cellular function and behaviour has always been interpreted in this context. Consistently observed changes in pre-conceptual maternal and uterine artery blood flow, abdominal pregnancy implantation, and late pregnancy have been challenging this concept, and suggest that abnormal placental perfusion may result in trophoblast impairment, rather than the other way round. This review focuses on evidence that maternal cardiovascular function plays a significant role in the pathophysiology of preeclampsia.

scholarly journals P07.04: Uterine artery blood flow volume is reduced in human pregnancies with increase utero-placental downstream impedance

2006 ◽  
Vol 28 (4) ◽  
pp. 569-569
Author(s):  
S. Boito ◽  
S. Rigano ◽  
G. Pennati ◽  
L. Mandia ◽  
A. Padoan ◽  
...  
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Flow Volume ◽  
Artery Blood Flow ◽  
Blood Flow Volume

scholarly journals Activation of angiotensin type 2 receptor attenuates testosterone-induced hypertension and uterine vascular resistance in pregnant rats

2021 ◽  
Author(s):  
Jay S Mishra ◽  
Sathish Kumar
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Vascular Function ◽  
Uterine Artery ◽  
Artery Blood Flow ◽  
Protein Levels ◽  
Angiotensin Type 2 Receptor ◽  
Enos Protein ◽  
Angiotensin Type

Abstract Preeclampsia is a pregnancy-related hypertensive disorder with unclear mechanisms. While hypersensitivity to angiotensin II via vasoconstrictive angiotensin type-1 receptor (AT1R) is observed in preeclampsia, the importance of vasodilatory angiotensin type-2 receptor (AT2R) in the control of vascular dysfunction is less clear. We assessed whether AT1R, AT2R and eNOS expression is altered in placental vessels of preeclamptic women and tested if ex vivo incubation with AT2R agonist Compound 21 (C21; 1 μM) could restore AT1R, AT2R and eNOS balance. Further, using a rat model of gestational hypertension induced by elevated testosterone, we examined whether C21 (1 μg·kg−1·day−1, oral) could preserve AT1R and AT2R balance and improve blood pressure, uterine artery blood flow, and vascular function. Western blots revealed that AT1R protein level was higher while AT2R and eNOS protein were reduced in preeclamptic placental vessels, and AT2R agonist C21 decreased AT1R and increased AT2R and eNOS protein levels in preeclamptic vessels. In testosterone-dams, blood pressure was higher, and uterine artery blood flow was reduced, and C21 treatment reversed these levels similar to those in controls dams. C21 attenuated the exaggerated Ang II contraction and improved endothelium-dependent vasorelaxation in uterine arteries of testosterone-dams. These C21-mediated vascular effects were associated with decreased AT1R and increased AT2R and eNOS protein levels. C21 also increased serum nitrate/nitrite and bradykinin production in testosterone-dams and attenuated the feto-placental growth restriction. Thus, AT1R upregulation and AT2R downregulation is observed in preeclampsia and testosterone-model, and increasing AT2R activity could help restore AT1R and AT2R balance and improve gestational vascular function.

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