Acute administration of a single dose of valsartan improves left ventricular functions: a pilot study to assess the role of tissue velocity echocardiography in patients with systemic arterial hypertension in the TVE-valsartan study I

2006 ◽  
Vol 26 (6) ◽  
pp. 351-356 ◽  
Author(s):  
Satish C. Govind ◽  
Lars-Åke Brodin ◽  
Jacek Nowak ◽  
S. S. Ramesh ◽  
Samir K. Saha
Keyword(s):  
Single Dose ◽  
Pilot Study ◽  
Arterial Hypertension ◽  
Left Ventricular ◽  
Acute Administration ◽  
Systemic Arterial Hypertension ◽  
Tissue Velocity ◽  
Ventricular Functions

Prognostic role of Pro-BNP levels in left ventricular hypertrabeculation/non-compaction and neuromuscular disorders: results of a pilot study

2019 ◽  
Vol 67 (3) ◽  
Author(s):  
Norbert Malli ◽  
Nastasia Wilfinger-Lutz ◽  
Walter Krugluger ◽  
Claudia Stöllberger ◽  
Maria Winkler-Dwora K ◽  
...  
Keyword(s):  
Pilot Study ◽  
Neuromuscular Disorders ◽  
Left Ventricular ◽  
Prognostic Role

Left Ventricular Function in Patients with Pulmonary Arterial Hypertension: The Role of Two-Dimensional Speckle Tracking Strain

2016 ◽  
Vol 33 (9) ◽  
pp. 1326-1334 ◽  
Author(s):  
Ricardo de Amorim Corrêa ◽  
Fernanda Brito de Oliveira ◽  
Marcia M. Barbosa ◽  
Jose Augusto A. Barbosa ◽  
Taís Soares Carvalho ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Speckle Tracking ◽  
Left Ventricular ◽  
Two Dimensional ◽  
Pulmonary Arterial

scholarly journals Capability of B-Type Natriuretic Peptide (BNP) and Amino-Terminal proBNP as Indicators of Cardiac Structural Disease in Asymptomatic Patients with Systemic Arterial Hypertension

2005 ◽  
Vol 51 (12) ◽  
pp. 2245-2251 ◽  
Author(s):  
Thomas Mueller ◽  
Alfons Gegenhuber ◽  
Benjamin Dieplinger ◽  
Werner Poelz ◽  
Meinhard Haltmayer
Keyword(s):  
Arterial Hypertension ◽  
Natriuretic Peptide ◽  
Left Ventricular ◽  
Blood Concentrations ◽  
Hypertensive Patients ◽  
Amino Terminal ◽  
Systemic Arterial Hypertension ◽  
Cutoff Values ◽  
Asymptomatic Patients ◽  
Structural Disease

Abstract Background: The aim of the present study was to prospectively evaluate the diagnostic utility of B-type natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) measurements for the detection of cardiac structural disease in asymptomatic patients with systemic arterial hypertension and to test the hypothesis that the 2 analytes are equally useful in this clinical setting. Methods: We studied a consecutive series of 149 asymptomatic patients referred for echocardiographic evaluation of the cardiac effects of systemic arterial hypertension. Diagnosis of cardiac structural disease was based on the presence of systolic or diastolic dysfunction, left atrial dilatation, left ventricular dilatation or hypertrophy, pulmonary hypertension, and wall motion or valvular abnormalities. Blood concentrations of BNP and NT-proBNP were measured by 2 commercially available assays (Abbott AxSYM and Roche Elecsys, respectively). Diagnostic accuracies of BNP and NT-proBNP were assessed by ROC curve analysis. Areas under the curves were compared by analysis of equivalency. Results: In distinguishing between hypertensive patients with cardiac structural disease (n = 118) and hypertensive patients without (n = 31), areas under the curves were 0.740 (95% confidence interval, 0.662–0.808) for BNP and 0.762 (0.685–0.828) for NT-proBNP and were significantly equivalent (P = 0.015). Cutoff values with a 90% sensitivity for cardiac structural disease were 17 ng/L for BNP and 39 ng/L for NT-proBNP, with 29% and 32% specificity, respectively. Conclusions: BNP and NT-proBNP have similar capabilities for detecting cardiac structural disease in asymptomatic patients with systemic arterial hypertension. However, in the setting evaluated, a screening strategy relying on measurement of BNP or NT-proBNP may be of limited value because of the low specificity at the selected cutoff values.

Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension

2018 ◽  
Vol 69 (9) ◽  
pp. 2425-2429
Author(s):  
Carmen Gadau ◽  
Elena Ardeleanu ◽  
Roxana Folescu ◽  
Ioan Tilea ◽  
Andreea Varga ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Predictive Factors ◽  
Hdl Cholesterol ◽  
Arterial Disease ◽  
Left Ventricular ◽  
Cross Sectional ◽  
Systemic Arterial Hypertension ◽  
Peripheral Arterial ◽  
Made In

The present cross-sectional observational study was made in family medicine offices of Timi� County, Romania. The aim of the study was to investigate the prevalence of urinary microalbumin excretion (MAU) in resistant systemic arterial hypertension (RH), to analyze patients� biochemical and clinical characteristics, and the predictive factors for MAU. From a total number of 347 patients, MAU was detected in 76 cases (21.9%). The microalbuminuria positive patients were older, with significant higher office systolic blood pressure (BP) (155 � 13.50 vs 148 � 12.40 mmHg, p [ 0.0001) and diastolic blood pressure (94 � 12.20 vs 88 � 14.6 mmHg, p = 0.0013), higher prevalence of left ventricular hypertrophy, diabetes mellitus, obesity, ischemic and peripheral arterial disease. MAU positive patients presented statistical significant differences in biochemical data concerning: fasting plasma glucose (FPG) (118.80 � 32.02 vs 108.01 � 26.01 mg/dL, p = 0.003), impaired glucose tolerance (IGT) (10.52 % vs 4.94 %), glycated hemoglobin (HbA1c) (6.56 � 0.98% vs 5.96 � 0.91%, p [ 0.001), reduced estimated glomerular filtration rate (eGFR) (56.10 � 15.4 vs 69.30 � 17.5 ml/min/1.73m2, p [ 0.001) and higher potassium levels (4.71 � 0.43 vs 4.59 � 0.44 mg/dL, p = 0.0378). No significant differences were noticed regarding LDL- and HDL-cholesterol, triglycerides, uric acid and serum creatinine. In a logistic multivariate analysis independent predictors for MAU were: systolic BP (odds ratio, OR = 1.024, 95% confidence interval, CI:1.011-1.039, p [ 0.001), HbA1c (OR = 1.324, 95% CI: 1.078-1.724, p = 0.008) and eGFR (OR = 0.989, 95% CI: 0.977-0.999, p = 0.01). Our findings suggest that an important part of RH patients have microalbuminuria and highlight the importance of controlling its predictors, in order to improve patients� outcome.

Sign in / Sign up

Export Citation Format

Share Document